ADOLESCENT
MEDICINE
Saturday,
5/3/2003
8:30am–11:30
am
3150—Handheld
Computing for the Pediatrician (Part I) PDA 101:
Introduction To Handheld Computing for the Pediatrician
PAS
Mini Course
Chair: K. Johnson, Vanderbilt
University, Nashville, TN and A. Meyers, Boston University
Medical Center, Boston, MA
The use of handheld computers in medicine has grown
dramatically. This session is intended for those who have
a handheld computer (Palm or Pocket PC), or are
considering purchasing one, but who have not yet learned
how to use it. The goal of the session is to help the
beginner achieve a working familiarity with handheld
computing such that they will leave the session ready,
able and eager to use their own device in their daily life
and clinical practice. Ideally, all participants should
bring their own handheld. The session will include an
overview of the devices and their desktop software;
mastery of the basic (built-in) functions: datebook/calendar,
address book, memo pad, to-do lists; and add-on
applications: where to find them, how to install them and
what applications are available specific to clinical
pediatrics. Participants should be familiar with the use
of personal computers and the Internet, but no prior
knowledge of handheld computing is assumed.
- Introductions and Overview of Mini Course
- Lecture (with Audience Participation)—PDA Basics,
Hardware and Software, the Palm OS and Its Functions
- Palm OS Functions, Continued; PPC OS
- Medical and Pediatric Applications for the PDA
8:30am–11:30 am
3199c—Applying
for NIH Research Grants
Educational
Workshop
Pedro A. José, Professor of
Pediatrics and Physiology and Biophysics, Georgetown
University Medical Center, Washington, DC, Anshumali
Chaudhari, Scientific Review Administrator, Experimental
Cardiovascular Sciences Study Section, National Institutes
of Health, Bethesda, MD, Terry Rogers Bishop, Training and
Careers Program Director and Erythroid Lineage Genomics (ELGAP),
National Institutes of Health, Bethesda, MD and Linda L.
Wright, Deputy Director, Center for Research for Mothers
and Children, National Institute of Child Health and Human
Development, National Institutes of Health, Bethesda, MD
In the current climate of funding opportunities, the
ability to successfully obtain extramural support involves
applying for grants that are appropriate for an
investigator's career stage and drafting a clear and
focused application. In this session, we will discuss
career-stage-appropriate funding opportunities from the
NIH. We will also address how to write a grant
application, focusing on strategies with proven success.
The working of NIH study sections will be reviewed along
with how to best address the concerns of review panels. We
will also focus on how to obtain funding for fellowship
postdoctoral training and early stages of an academic
career.
8:30am–11:30 am
3201—Beyond
p Values—Inference in Clinical Research
Educational
Workshop
R. Wright and D. Shay, Department
of Pediatrics, Children’s Hospital, Boston, MA and
Centers for Disease Control
Background: Observational research studies have become
increasingly complex. The results of observational
research studies can be driven by properties other than
chance or causation. While these factors may drive the p
values of the results, they also change the appropriate
interpretation.
Workshop Methods: In the first half of this workshop,
we will formally define confounding, effect modification,
restriction vs. heterogeneity of exposure, intermediate
variables, selection bias and differential vs.
nondifferential information bias. In the second half, we
will use a case-based approach to illustrate examples of
studies in which the results are driven by these factors
and compare differences in the appropriate interpretation
in the presence and absence of these factors. Minimal math
skills will be needed, however, familiarity with basic
concepts of study design and data analysis (case control
vs. cohort study, interpretation of Ors, etc.) is
recommended. We will specifically illustrate examples of
effect modification vs. confounding, intermediate
variables vs. confounding, selection bias, underpowered
studies, and the role of measurement error in determining
effect estimates.
9:15am–12:15 pm
3300—Cancer
in Adolescents and Young Adults: Ultimate Paradigm of
Adolescent Medicine?
PAS/ASPHO
Mini Course
Chair: Archie Bleyer, The
University of Texas M. D. Anderson Cancer Center, Houston,
TX
The primary objective of this mini course is to convey
the array of issues intrinsic to caring for older
adolescents and young adults with chronic, life
threatening disease. For several reasons, cancer provides
an ideal paradigm for this adolescent/young adult
challenge.
1. The spectrum of disease is broader for cancer at
many levels of biological organization than it is for any
other disease. Virtually all organ systems and organs may
be diseased in patients with cancer, whether due to the
disease or its treatment. The affected organs include CNS,
hematopoeitic, cardiovascular, hepatic, renal, endocrine,
musculoskeletal, immune, pulmonary, gastrointestinal,
cutaneous, ocular, otic and oral tissues.
2. The affected levels of biological organization
include molecular, cellular, tissue, organ, organ system,
connective, and psychological. The latter is particularly
challenging among adolescents with cancer.
3. The clinical and translational research programs in
oncology are among the most organized medical enterprises
at the national and tertiary center level in all of
medicine, with the cooperative infrastructure that has
supported this success among the most successful in the
history of science. The advances among children with
cancer have been among the most dramatic in the history of
medicine.
4. Despite the organizational achievements, there is
emerging evidence that patients with cancer in this age
group have been ignored relative to the scientific and
clinical focus that has been successfully applied to
younger and older patients with malignant disease.
Overview
Archie Bleyer, The University of
Texas M. D. Anderson Cancer Center, Houston, TX
The Adolescent and Young Adult Gap in Cancer Care and
Outcome
Jeffrey Carlton Murray, Cook
Children's Medical Center, Fort Worth, TX
Sarcomas in Young Adults: Strategies for Enhanced
Accrual to Clinical Trials
Karen Albritton, Primary Children's
Medical Center, Huntsman Cancer Center, Salt Lake City, UT
Adolescent and Young Adults with Malignant Disease:
What Will It Take To Improve Outcome?
Archie Bleyer, The University of
Texas M. D. Anderson Cancer Center, Houston, TX
The Survivor Transition Challenge
Kevin Charles Oeffinger, University
of Texas Southwestern Medical School, Dallas, TX
Sponsored jointly with the American Society of
Pediatric Hematology/Oncology
12:00pm–3:00 pm
3501—Handheld
Computing for the Pediatrician (Part II) PDA 102:
Intermediate/Advanced Handheld Computing for the
Pediatrician
PAS
Mini Course
Chair: K. Johnson, Vanderbilt
University, Nashville, TN and A. Meyers, Boston University
Medical Center, Boston, MA
The field of medicine is replete with examples of ways
that handheld computers may be used to educate, organize
and inform clinicians. There are also examples of how
researchers may benefit from this technology. During this
more advanced session, we will discuss some of these uses
of handheld computers. We will provide examples of
software in a variety of domains and discuss their
historical, current and future use. We also will
demonstrate some future technology and discuss its
implications. At the conclusion of this session,
participants will have increased familiarity with
state-of-the-art applications, techniques to install them
and the future of handheld computers and wireless
networking.
- Introductions and Overview of Mini Course
- Lecture with Audience Participation: The Top 10
Novel Uses of PDAs in Health Care
- Exercises and Demonstrations
12:00pm–3:00 pm
3503—Science
of Gateway Drugs: Tobacco, Marijuana and Alcohol
PAS
Mini Course
Chair: Donald E. Greydanus,
Michigan State University Kalamazoo Center for Medical
Studies, Kalamazoo, MI
Tobacco, marijuana and alcohol have long been
recognized as the "gateway drugs" or the drugs
adolescents first begin to abuse. Each drug has inherent
dangers, one of which is they can serve as stepping stones
to abuse of other drugs. This session will review current
issues involved with each of these three drugs—issues
that involve the pediatric researcher and clinician as
well as society itself. The first hour will be devoted to
tobacco, the second to marijuana and the final to alcohol.
Questions and answers will be encouraged from the
audience.
Overview/Introductions
Donald E. Greydanus, Michigan State
University Kalamazoo Center for Medical Studies,
Kalamazoo, MI
Tobacco
Dilip R. Patel, Michigan State
University College of Human Medicine, Kalamazoo Center for
Medical Studies, Kalamazoo, MI
Marijuana: An Overview
Richard H. Schwartz, University of
Virginia Medical School, Charlottesville, VA
Alcohol
John R. Knight, Children's Hospital,
Harvard Medical School, Boston, MA
1:00pm–3:00 pm
3701c—Adolescent
Medicine: What Up? A Primer on the Anticipatory Guidance
Interview
Educational
Workshop
Cora Collette Breuner, Assistant
Professor of Pediatrics, Children's Hospital and Medical
Center, Seattle, WA
The period of adolescence encompasses dramatic changes,
both physical and emotional. Taking care of these youth
requires not only patience, compassion and flexibility but
also knowledge of the biologic, psychological and cultural
transformations. Adolescents aged 11–21 years made 61.8
million visits to physicians in 1994 and continue to see
their primary care providers for continuity health care.
There is a terrific opportunity for preventive health
interviewing in these visits. In this workshop, the
participants will become familiar with GAPS and Bright
Future Guidelines for the adolescent visit, as well as
effective coding and billing procedures. There will also
be a panel of adolescents who will talk about how they
want to be interviewed and provide insight into positive
and negative experiences that they have had during their
health visits.
1:00pm–3:00 pm
3702c—Career
Paths for Clinician-Educators: Enhancing the Career
Development of Clinician-Educators
Educational
Workshop
Robert I. Hilliard, Professor of
Pediatrics, Department of Pediatrics, Hospital for Sick
Children, University of Toronto, Toronto, ON, Canada,
Karen Leslie, Assistant Professor, Department of
Pediatrics, University of Toronto, Toronto, ON, Canada and
Ann Jefferies, Assistant Professor, Department of
Pediatrics, University of Toronto, Toronto, ON, Canada
Clinician-educators are those physicians whose career
activities combine patient care and teaching and whose
scholarly activities promote excellence in medical
education. With this interactive workshop, it is expected
that participants will learn a practical approach to their
career development and will:
- have a better understanding of the motivations,
career plans and challenges of clinician-educators;
- be able to develop a career ‘map’ for junior
clinician-educators;
- learn how a mentoring program can help the
clinician-educator plan and develop his/her career,
including suggestions on how mentors and ‘mentees’
can contribute to enhancing professional academic
skills;
- be able to identify faculty development needs and
participate in useful and effective faculty
development activities, having a better understanding
of specific faculty development activities and the
evidence for the effectiveness of these activities;
and
- have a better understanding of the evaluation of
teachers and how these evaluations are used for
faculty development and promotion and will learn
guidelines for developing an effective Teaching
Dossier.
This workshop will be of interest to both junior
faculty with an interest in developing their academic
careers as clinician-educators and to administrators
responsible for supporting junior faculty in the areas of
teaching and education.
1:00pm–3:00 pm
3704c—So
You Want To Be an Author
Educational
Workshop
Chair: Catherine D. DeAngelis,
Editor-in-Chief, JAMA, Chicago, IL
This interactive session will provide the attendee with
basic information on publication of a manuscript, as
derived from the perspective of an editor. Issues (with
data provided when possible) to be discussed are:
A. View from the Inside
- Characters involved
- Manuscript flow
- Peer review process
- Working with the author
B. View From the Outside
- How to choose the right journal for your paper
- How to prepare the cover letter
- How to prepare the abstract
- How to prepare the body of the manuscript
- How to prepare the references
C. Conflict of Interest and Ethics
3:15pm–5:15 pm
3802—General
Pediatrics: Obesity
Original
Science Abstracts - Platform Session
Moderators: Jan Edwin Drutz and
Ivor Braden Horn
3:15pm–5:15 pm
3850c—An
Innovative Approach to Self-Directed Professional
Development and Lifelong Learning
Educational
Workshop
Henry H. Bernstein, Associate
Professor of Pediatrics, Harvard Medical School, Boston,
MA and Carol Carraccio, Professor of Pediatrics,
University of Maryland School of Medicine, Baltimore, MD
The 21st century heralds a paradigm shift in medical
education with a focus turned to competence and outcomes.
The Accreditation Council for Graduate Medical Education (ACGME)
is spearheading a competency-based system of graduate
medical education coincident with the American Board of
Pediatrics’ (ABP) initiative to transition from periodic
"recertification" to "maintenance of
certification." Our greatest challenge as educators
lies in developing tools to evaluate competence during
training and to equip all trainees with the skills
necessary to achieve quality continuous professional
development in order to maintain their certification in
pediatrics.
The overarching goal of this workshop is to explore the
value of using technology as a tool for promoting
self-assessment and lifelong learning in continuous
professional development. We will demonstrate how
physicians can use an innovative web-centered tool to
document competence in practice-based learning and
improvement. Participants will discover how to create and
manage a personal list of educational needs based on their
professional experiences, develop individualized learning
plans to address these needs and then document the impact
of learning on their practice.
The outcome of implementing this web-based technology
will be the ability to demonstrate competence of our
trainees in the domain of practice-based learning and
improvement to the ACGME and the preparation of
tomorrow’s physicians to demonstrate evidence of
continuous professional development in maintaining their
certification.
3:15pm–5:15 pm
3853c—Who
Decides? Bioethical Dilemmas in Pediatrics
Educational
Workshop
Susan Albersheim, Clinical
Professor, Department of Pediatrics, British Columbia's
Children's Hospital, Vancouver, BC, Canada and Joel E.
Frader, Professor of Pediatrics/Medical Ethics and
Humanities, Feinberg School of Medicine, Northwestern
University, Chicago, IL
What should you do when parents want you to continue
burdensome treatments, which you think are futile? What
should you do when parents want you to stop intensive care
treatment, the continuation of which you think is in the
best interests of the child? Who ought to make decisions
for the not yet competent? Is it the parents, the doctors,
the ethics committee, society or some other disinterested
third party? The goal of this seminar is to consider the
complexity of these difficult decisions, looking at
factual and evaluative considerations. Through interactive
case discussion we will identify the problems and
potential pitfalls in decision-making for the pediatric
population.
Sunday, 5/4/2003
8:00am–10:00 am
4101—Pediatrics
and Public Health
PAS
Topic Symposium
Chair: Ruth A. Etzel, The George
Washington University School of Public Health and Health
Services, Washington, DC
The purpose of this symposium is to describe the
benefits to pediatricians of collaborating with public
health specialists and to offer examples of some effective
collaborations. Speakers will identify resources available
to pediatricians who want to engage in public health
efforts.
How Pediatricians Can Use Healthy People 2010
Objectives for the Nation
Peter C. van Dyck, Health Resources
and Services Administration, Rockville, MD
Using Principles of Population-Based Medicine To
Implement Disease Prevention and Health Promotion
Strategies in Pediatric Practice
Arthur B. Elster, American Medical
Association, Chicago, IL
Pediatrician Involvement in Prevention of Violence
Katherine Kaufer Christoffel,
Feinberg School of Medicine at Northwestern University,
Children's Memorial Institute for Education &
Research, Chicago, IL
Integration of Pediatrics and Public Health—An
Academic Medicine-Public Health Health Model
Jeffrey L. Goldhagen, University of
Florida, Jacksonville, Florida
Discussion
8:00am–10:00 am
4102—Smallpox
and Bioterrorism Preparedness Planning
PAS/PIDS
Topic Symposium
Chair: John F. Modlin, Children's
Hospital at Dartmouth/Dartmouth Medical School, Lebanon,
NH
This program will give a "pediatric
perspective" to smallpox bioterrorism preparedness
planning efforts now under way within federal, state and
local public health agencies. It will include a review of
smallpox epidemiology, clinical disease, smallpox (vaccinia)
vaccine and lessons learned from the WHO Smallpox
Eradication Program. The nature of the current threat and
responses to that threat will be discussed.
Smallpox Epidemiology and Clinical Disease
Walter A. Orenstein, National
Immunization Program, Centers for Disease Control and
Prevention, Atlanta, GA
Surveillance/Control Methods
J. Michael Lane, Formerly Director,
Smallpox Eradication Program, CDC, Atlanta, GA
Smallpox (Vaccinia) Vaccine: Efficacy and Complications
John M. Neff, Children’s Hospital
and Regional Medical Center, Seattle, WA
Smallpox Bioterrorism Preparedness Planning
John F. Modlin, Children's Hospital
at Dartmouth/Dartmouth Medical School, Lebanon, NH
Sponsored jointly with the Pediatric Infectious
Diseases Society
8:00am–11:00 am
4250—Pediatric
and Adolescent Psychopharmacology: Current EBM in 2003
PAS
Mini Course
Chair: Donald E. Greydanus,
Michigan State University Kalamazoo Center for Medical
Studies, Kalamazoo, MI
The use of psychopharmacologic agents in children and
adolescents has increased significantly over the past
decade. Clinicians are becoming more involved in using
these various medications, and this trend will continue in
the future. What is the evidence-based medicine (EBM) for
these medications as they apply to children and
adolescents? This mini course will review the current
research as applied to antidepressants, stimulants, mood
stabilizers and antipsychotics. Applications to mental
disorders in children and adolescents will be discussed.
Questions from the audience will be encouraged.
Overview/Introductions
Donald E. Greydanus, Michigan State
University Kalamazoo Center for Medical Studies,
Kalamazoo, MI
Antidepressants
Susan Smiga, Langley Porter
Psychiatric Institute, University of California, San
Francisco, CA
Stimulants
Glen R. Elliott, Langley Porter
Psychiatric Institute, University of California, San
Francisco, CA
Mood Stabilizers
Glen R. Elliott, Langley Porter
Psychiatric Institute, University of California, San
Francisco, CA
Antipsychotics
Chris Varley, University of
Washington Medical Center, Children's Hospital and
Regional Medical Center, Seattle, WA
2:00pm–4:00 pm
4600—Pediatric
Solid Organ Transplantation in the 21st Century
PAS/ASPN/AST/LWPES/NASPGHAN
Topic Symposium
Chairs: Ellis D. Avner,
President, ASPN, Mitchell B. Cohen, President, NASPGHAN
and Mark A. Sperling, President, LWPES
Organ transplantation remains the final therapeutic
option for many patients with chronic diseases of many
organ systems. Extraordinary advances in molecular and
cellular biology have led to new immunological approaches
which should make the holy grail of immune tolerance a
reality for the 21st century. This symposium will focus on
the exciting advances in four areas of pediatric solid
organ transplantation: pancreatic organ and islet
transplantation as a cure for diabetes, hepatic
transplantation for chronic hepatic and metabolic disease,
renal transplantation for end stage renal disease and
small bowel transplantation for previously untreatable
catastrophic bowel injury. This symposium is proudly
sponsored by the American Society of Pediatric Nephrology
(ASPN), the North American Society of Pediatric
Gastroenterology, Hepatology and Nutrition (NASPGHAN), and
the Lawson Wilkins Pediatric , and supported by funding
from the American Society of Transplantation and the
Juvenile Diabetes Research Foundation International
Evolving Therapeutic Role of Transplant Therapies for
T1DM
David M. Harlan, National Institutes
of Health, Bethesda, MD
Hepatic Transplantation—Controversies and Challenges
Suzanne V. McDiarmid, University of
California, Los Angeles, CA
Renal Transplantation—Approaching the Holy Grail
William E. Harmon, Harvard Medical
School, Children's Hospital, Boston, MA
Small Bowel Transplantation—Ready for Prime Time
Simon P. Horslen, University of
Nebraska Medical Center, Omaha, NE
Sponsored jointly with the American Society of
Pediatric Nephrology, American Society of Transplantation,
North American Society of Pediatric Gastroenterology,
Hepatology and Nutrition and Lawson Wilkins Pediatric
Endocrine Society
Supported by an educational grant from the American
Society of Transplantation and Juvenile Diabetes Research
Foundation International
2:00pm–4:00 pm
4631c—The
Art of Lecturing
Educational
Workshop
Beverly Wood, Professor of
Radiology & Pediatrics, Keck School of Medicine,
University of Southern California
Receive helpful pointers to make your talks memorable
and useful. This session will introduce methods of
planning and organizing presentations, preparing and
designing visual aids, handouts and clear delivery.
2:00pm–5:00 pm
4664—I
Can Do That! Preparing Residents To Perform Minor
Procedures
Educational
Workshop
S. Selbst, J. Loiselle and M.
Attia, A.I. duPont Hospital for Children, Wilmington, DE
and J. Fein, N. Tsarouhas and J. Zorc, The Children’s
Hospital of Philadelphia, Philadelphia, PA
The performance of minor procedures is an important
part of pediatric residency and office practice. However,
training and performance of certain procedures varies
between residency programs. Because of limited exposure,
pediatric residents and practitioners may avoid a
procedure, or call a consultant, when uncomfortable with a
technique. The goal of this workshop is to convey specific
techniques and instruction methods for minor office
procedures. This hands-on workshop will demonstrate skills
and afford practice as participants rotate through the
following stations:
- Newer concepts in wound repair—use of glue, fast
absorbing sutures, staples.
- Remove foreign bodies from ears, nose, eyes;
reimplant an avulsed tooth.
- Troubleshoot gastrostomy tube and tracheostomy tube
complications.
- Skin extrications: embedded fishhook, subungual
hematomas, hair tourniquet.
- Vascular access—learn the technique and new
indications for intraosseous infusions; master new
needleless systems and safety devices for IV.
- Genital issues: fix paraphimosis, zipper entrapment,
rectal prolapse.
Workshop leaders will underscore the importance of
learning technical skills in pediatrics. Participants
should become adept at several procedures and will be able
to teach them to others. The participants will also be
asked to share their ideas and experiences in teaching and
practicing common technical procedures.
2:00pm–5:00 pm
4668—Terrorism
and Children
Educational
Workshop
R. Leggiadro, A. Fine, S. Shelov
and G. Foltin, Hackensack University Medical Center,
Hackensack, NJ, New York City Dept of Health, New York,
NY, Maimonides Medical Center, Brooklyn, NY and NYU School
of Medicine, New York, NY
The 2001 World Trade Center and anthrax attacks
established terrorism as a reality in this country. In
addition to anthrax, critical biological agents include
smallpox, plague, tularemia, botulinum toxin, and viral
hemorrhagic fever. Release of sarin nerve gas in the Tokyo
subway system by the Aum Shinrikyo cult in 1995 resulted
in some 5,000 casualties, including 12 deaths, and the
threat of a radiation incident perpetrated by terrorists
is also real. Pediatricians have a key role in the
management of illness after a terrorist incident,
including biological, chemical or nuclear releases.
Effective preparedness requires an increased index of
suspicion for unusual diseases or clusters of illness,
with prompt reporting to public health authorities to
facilitate recognition of an outbreak and subsequent
intervention. Psychological effects of a domestic
terrorist disaster on children will also need to be
managed appropriately. This workshop will address the
epidemiologic, clinical, preparedness and response issues
relevant to biological, chemical and nuclear threats to
children, who are especially vulnerable. Specific and
detailed diagnostic and management information will be
provided, as well as emergency contact and educational
resource information.
2:30pm–4:30 pm
4760—The
Changing Spectrum of Pediatric Specialty Care: Implication
for Pediatric Generalist and Specialist
PAS
State of the Art
Chair: Russell Chesney,
University of Tennessee Health Science Center, Memphis, TN
In the face of dramatic alterations in health care
delivery during the 1990s, the roles of pediatric
generalists and subspecialists have changed. This has led
to national debate as to how general pediatricians and
subspecialists should be trained, how they should interact
and what final product or solution is desired. Both the
United States and Canada are affected by these changes. In
this session three experts will cover important aspects of
this emerging problem.
Overview
Russell W. Chesney, University of
Tennessee Health Science Center, Memphis, TN
Distribution of Generalist and Subspecialist Care for
Children: A Moving Target
Julia A. McMillan, Johns Hopkins
University School of Medicine, Baltimore, MD
Subspecialty Pediatrics in Canada
Robert H.A. Haslam, University of
Toronto, Hospital for Sick Children, Toronto, Ontario,
Canada
Who Cares for Children with Chronic Conditions?
James M. Perrin, Mass General
Hospital for Children, Harvard Medical School, Boston, MA
Discussion
Sponsored jointly with the Public Policy Council of the
APS, AMSPDC, SPR and the Public Policy Committee of the
APA
3:15pm–6:15 pm
4800—Getting
the Fat Out: A Practical Approach to Pediatric Lipid
Disorders
PAS/LWPES
Mini Course
Chairs: Brian W. McCrindle, The
Hospital for Sick Children, Toronto, Ontario, Canada and
Charlotte M. Boney, Rhode Island Hospital, Providence, RI
This course will review the evaluation and treatment of
lipid disorders in children. Although diet and obesity are
the most common causes of lipid disorders in children, the
practitioner needs to be able to distinguish familial from
acquired hyperlipidemias. The format will include four
speakers who will present 1) lipoprotein biosynthesis and
metabolism, primary (familial) versus secondary (acquired)
disorders and selective screening; 2) dyslipidemia of
obesity and insulin resistance; 3) non-pharmacologic
treatments of managing dietary changes and obesity; and 4)
the pharmacologic treatment of primary hyperlipidemias.
Each session will include examples of the practical
application of the material. The course will conclude with
a panel discussion of the speakers with plenty of time for
questions.
Overview of Lipoprotein Biosynthesis, Metabolism and
Disorders and Screening
Ellis J. Neufeld, Children's
Hospital, Boston, MA
The Dyslipidemia of Obesity and the Insulin Resistance
Syndrome
Julia Steinberger, University of
Minnesota, Minneapolis, MN
Non-Pharmacologic Treatment of Hyperlipidemias
Barbara A. Dennison, Research
Institute, Bassett Healthcare, Cooperstown, NY
The Pharmacologic Treatment of Hyperlipidemias
Brian W. McCrindle, The Hospital for
Sick Children, Toronto, Ontario, Canada
Discussion
Sponsored jointly with the Lawson Wilkins Pediatric
Endocrine Society
3:45pm–6:15 pm
4849—Current
Research Issues in STDs and Adolescents: Chlamydia,
Genital Herpes and Human Papillomavirus Infection
PAS/PIDS
Topic Symposium
Chair: Donald E. Greydanus,
Michigan State University Kalamazoo Center for Medical
Studies, Kalamazoo, MI
This session reviews current research principles in
selected sexually transmitted diseases. First, clinical
epidemiology and prevention issues for Chlamydia
trachomatis are considered, emphasizing rescreening
(delayed retesting of infected persons), novel strategies
for ensuring partner treatment, and the role of male
screening in disease control. Then, new directions in
public health and prevention aspects of genital herpes are
outlined. An update of the HSV vaccine is presented.
Finally, human papillomavirus (HPV) is considered,
including new recommendations in human papillomavirus
testing, triage of abnormal Pap smears and the current
status of HPV vaccines. Questions are encouraged from the
audience.
Chlamydia Prevention in Teens: New Directions
H. Hunter Handsfield, University of
Washington and Public Health - Seattle & King County,
Seattle, WA
Genital Herpes
Anna Wald, University of Washington
Virology Research Clinic, Seattle, WA
Human Papillomavirus Infection
Anna-Barbara Moscicki, Glaser
Pediatric Research Network, University of California, San
Francisco, CA
Epidemiology of STDs in Children and Adolescents:
Perspectives from the World Health Organization
Sibongile Dludlu, World Health
Organization, Geneva, Switzerland
Sponsored jointly with the Pediatric Infectious
Diseases Society
Monday, 5/5/2003
8:00am–10:00 am
5152—Immunization
Delivery
Original
Science Abstracts - Poster Symposium
Chair: Robert M. Jacobson and
Lance E. Rodewald
9:00am–12:00 pm
5202—Faculty
Development Workshop in Clinical Pediatric Sleep Medicine
Educational
Workshop
J. Owens and V. Dalzell, J.
Mindell, Dept. of Pediatrics, Brown University,
Providence, RI and Dept. of Pediatrics, Children's
Hospital of Philadelphia, PA
Recent studies suggest that pediatric sleep issues,
despite their clinical importance, are inadequately
addressed in the practice setting. Most medical schools
and post-graduate pediatric training programs do not offer
sufficient educational opportunities to allow students and
residents to acquire the necessary knowledge and skills to
diagnose and treat these problems. The goal of this
workshop is to teach clinical pediatric faculty how to
become more effective teachers of pediatric sleep
medicine. Interactive presentations will focus on
developing and adapting sample core curriculums for
medical students and residents in pediatric sleep,
development and application of teaching strategies in a
variety of settings (inpatient, continuity clinics,
behavioral pediatrics rotations, etc.), use of teaching
materials and resources (sample cases, web-based
materials, etc.) and evaluation tools (pre and post-tests,
OSCEs, etc.) to enhance precepting skills of participants.
Videotaped standardized patient encounters of common
pediatric sleep problems will also be reviewed and
discussed. Participants will also be encouraged to bring
sample pediatric sleep cases from their own practices in
order to offer participants the opportunity to review and
operationalize acquired skills.
9:00am–12:00 pm
5203—Family
Presence for Procedures—Trying To Please Everyone
Educational
Workshop
S. Selbst, K. Bradford, A. Pratt,
S. Kost and A. Renwick, A.I. duPont Hospital for Children,
Wilmington, DE and Jefferson Medical College,
Philadelphia, PA
Family presence for procedures is a relatively new
concept in pediatric medicine. Studies have shown that
many parents prefer to be with their children when they
undergo painful or invasive procedures. Some physicians
are reluctant to accept this break with tradition and
refuse to allow parents in the room. The purpose of this
workshop is to develop an approach to successful
procedures with parental presence. Workshop leaders
(including physicians, social work, housestaff) will
address critical issues such as:
- Review of the literature—what do parents/families
want?
- What is best for the children?
- What rights do the parents have? How about the
physicians?
- Are some situations/procedures (i.e.,
resuscitations) "off-limits"?
- How can we instill confidence in trainees when the
family is watching?
- Can we preserve teaching opportunities?
- Are there safety risks? Legal issues?
- Enlisting the help of others: the role of liaisons,
social workers, therapists
Using case scenarios and role-playing, workshop leaders
will address the pros and cons of family presence for
procedures. Participants will be expected to share their
experiences and ideas to move forward with this
"unconventional" approach to medical care. It is
expected that through discussion and debate we will
implement a system for success.
9:00am–12:00 pm
5206—Navigating
the Legal Waters in Clinical Medicine: A Primer for
Pediatricians
Educational
Workshop
J. Klig, M. Flomenbaum, L.
Arnold, C. Baum, K. Bechtel, K. Santucci and M. D. Baker,
Section of Pediatric Emergency Medicine, Yale-New Haven
Children’s Hospital, New Haven, CT and Office of Chief
Medical Examiner, New York, NY
The incidence of lawsuits in the United States
continues to rise. Within this environment, pediatricians
are vulnerable to litigation yet often have limited
experience and information about the legal process and
relevant principles of law. Legal dilemmas are
particularly common in acute care settings and frequently
are managed without the immediate advice of counsel. In
this workshop, participants will explore basic legal
issues that impact on medical practitioners, gain
familiarity with the litigation process and examine
strategies for testifying in court. A team of specialists
in pediatric emergency medicine, malpractice issues, court
testimony and forensic medicine will begin the workshop
with an interactive presentation of case scenarios that
highlight common statutory dilemmas, malpractice issues
and the litigation process (civil and criminal).
Participants will then view videotapes of court testimony
and discuss strategies for testifying as a fact or expert
witness. Workshop leaders and participants will conclude
the session with small group discussions of individual
experiences with civil or criminal proceedings and legal
testimony. A complete syllabus will be provided for the
workshop that is designed for use as a teaching manual.
9:00am–12:00 pm
5253—Environmental
Health
Special
Interest Group
Chairs: Benjamin Gitterman,
bgitterm@cnmc.org and James Roberts, robertsj@musc.edu
The Pediatric Environmental Health Special Interest
Group is looking forward to another excellent meeting at
the Pediatric Academic Societies in Seattle in May 2003.
We hope you will join us for an informative session. Our
keynote speaker will be Dr. Michael Weitzman who will be
discussing some of the latest information about
children’s environmental health, including the
neurocognitive effects of environmental tobacco smoke.
Further program details are forthcoming. Since our May
2002 SIG meeting, we have slowly begun the process of
looking to update and perform a major overhaul of a
faculty teaching manual to teach Pediatric Environmental
Health that was developed and initially revised by the
Children’s Environmental Health Network—a Train the
Trainers manual. We hope to invite additional
participation when this project moves forward. We hope to
see you in Seattle and sustain the momentum of increasing
attendance annually at our sessions!
10:15am–12:15 pm
5350—Bone
Health
PAS/LWPES
Topic Symposium
Chair: Catherine Gordon,
Children's Hospital, Boston, MA
Healthy bones in childhood are of vital importance, for
they determine future bone health or disease in adulthood.
In this symposium, recent advances in the understanding of
the biology of bone formation and turnover will be
discussed. Clinical disorders affecting pediatric bone
health, and the assessment of their impact, will be
presented. The controversial issue of whether breast-fed
babies should be given supplemental vitamin D will be
considered next. Finally, recent advances in the use of
new anti-resorptive agents in the treatment of metabolic
bone diseases of children will be presented.
Basic Biology of Bone
Gerard Karsenty, Baylor College of
Medicine, Houston, TX
Disorders Affecting Pediatric Bone Health and Their
Assessment
Laura K. Bachrach, Stanford
University Medical Center, Stanford, CA
Is Vitamin D Supplementation Indicated in Breast–fed
Infants?
Thomas O. Carpenter, Yale University
School of Medicine, New Haven, CT
Bisphosphonates in the Treatment of Metabolic Bone
Disease
Frank Rauch, Shriners Hospital for
Children, McGill University, Montreal, Canada
Sponsored jointly with the Lawson Wilkins Pediatric
Endocrine Society
10:15am–12:15 pm
5400—Adolescent
Medicine I
Original
Science Abstracts - Platform Session
Moderator: Donald E. Greydanus
12:15pm–1:00 pm
5525—2003
Special Presentation: Responding to the Quality Crisis
PAS
Special Presentation
Chair: Carden Johnston,
President-elect, American Academy of Pediatrics
Overview
Carden Johnston, The Children's
Hospital, Birmingham, AL
Al Aynsley-Green, National Clinical Director for
Children, Department of Health, Her Majesty's Government,
Nuffield Professor of Child Health, The Institute of Child
Health, University College London
University of London, Director of Clinical Research &
Development, Great Ormond Street Hospital for Children and
The Institute of Child Health, London
Discussion
What happens when there is a public national concern
about excessive poor outcomes at a Children's Medical
Center? This was the scenario in Bristol, England, where a
crisis in the outcome of children after cardiac surgery
developed even when well–trained, committed, concerned
clinicians and subspecialists were intimately involved.
Because of this, Professor Al Aynsley-Green, President of
the Academic Paediatricians, was appointed to the new post
of National Clinical Director for Children by Parliament
and to Chair a Children's Taskforce to answer the question
of how can such a negative experience like this be turned
into positive outcomes for children? He is charged to
secure the health and well-being of all children
throughout childhood into adult life by developing a
National Service Framework for children's services across
health, social care and education.
Lessons he has learned and experiences he has lived
will be shared to help pediatricians around the world with
our quest to improve the lives and health of children. The
goals, activities and experiences of the Children's
Taskforce, as well as six external working groups, are
exportable, practical and logical. Strategies used for
developing opportunities not only to improve child health
at a local level but also at a national level will be
discussed.
Opportunities for questions and discussion will be
provided so attendees can share effective techniques to
improve child life and health.
Sponsored jointly with the American Academy of
Pediatrics
1:00pm–3:00 pm
5570A—Hypertension—Related
Target Organ Damage in Children
ASPN
Symposium
Chair: Joseph Flynn, Montefiore
Medical Center, Bronx, NY and Jonathan Sorof, UT-Houston
Medical School, Houston, TX
Hypertension–Induced Vascular Injury
Samuel S. Gidding, A.I. DuPont
Institute, Wilmington, DE
Detection of Target Organ Damage
Stephen R. Daniels, University of
Cincinnati College of Medicine, Cincinnati, OH
What Is the Blood Pressure Threshold for Development of
Target Organ Damage in Children
Jonathan M. Sorof, UT-Houston
Medical School, Houston, TX
Pathophysiology of Microalbuminuria in Hypertension and
Reversibility with Treatment
George Bakris, St. Luke's Medical
Center, Chicago, IL
3:00pm–5:00 pm
5654—Vaccines–2003
PAS/PIDS
Topic Symposium
Chair: Stanley A. Plotkin,
Aventis Pasteur and the University of Pennsylvania,
Doylestown, PA
This symposium covers four issues in vaccination. The
American Academy of Pediatrics and CDC currently are
moving toward a recommendation for universal annual
vaccination of infants with killed or live influenza
vaccine. Why is this? Now that Rotashield is off the
market, a new rotavirus vaccine is needed and may be on
the way. Despite good protection of children by
vaccination, pertussis infections are rising in
adolescents and adults. Can they be controlled? Recent
disruptions in vaccine supply have caused pediatricians
significant problems. What are the causes and solutions?
Universal Influenza Vaccination in Children
W. Paul Glezen, Baylor College of
Medicine, Houston, TX
New Rotavirus Vaccines: After Rotashield
Paul A. Offit, Children's Hospital
of Philadelphia, Philadelphia, PA
Adolescent and Adult Pertussis Vaccination
Kathryn M. Edwards, Vanderbilt
University School of Medicine, Nashville, TN
Vaccine Shortages: Causes and Effects
Walter A. Orenstein, National
Immunization Program, Centers for Disease Control and
Prevention, Atlanta, GA
Sponsored jointly with the Pediatric Infectious
Diseases Society
3:00pm–5:00 pm
5708—Pediatric
Nutrition: Obesity
Original
Science Abstracts - Poster Symposium
Moderators: Nancy F. Krebs and
Sharon E. Oberfield
5:30pm–7:30 pm
5950A—Open
Workshop: What Ancillary Studies Should Accompany a
Multicenter, National Clinical Trial for Focal Segmental
Glomerulosclerosis?
ASPN
Workshop
Chair: Bill Schnaper,
Northwestern University, Chicago, IL and Marva Moxey-Mims,
NIH/NIDDK/DKUH, Bethesda, MD
Tuesday, 5/6/2003
8:00am–10:00 am
6120—Adolescent
Medicine II
Original
Science Abstracts - Poster Symposium
Chair: Donald E. Greydanus and
David W. Kaplan
8:00am–10:00 am
6126—Health
Services Research
Original
Science Abstracts - Platform Session
Chair: Dimitri A. Christakis and
Simon J. Hambidge
8:45am–11:45 am
6204—Conflict
of Interest in Pediatric Research
Educational
Workshop
R. A. Etzel and J. Frader, APA
Research Committee
Recent financial scandals affecting successful and
respected companies have focused public attention on
conflicts of interest involving corporate officers,
stockholders, and customers. In the medical research
world, too, recent events have raised questions about
conflicts of interest affecting investigators, research
subjects and patients. Examples of the latter include the
financial interests of gene-transfer experimenters (the
Gelsinger case at the University of Pennsylvania) and
study goals versus individual subject/patient interests in
the Kennedy Krieger law suit (Hopkins lead abatement
study). Despite the potential pitfalls, pediatric
researchers receive only perfunctory training in handling
them. This workshop will provide investigators with a
framework for and experience with considering real and
perceived conflicts of interest in their research. We seek
to provide guidance and support for investigators who need
to recognize and face ethical concerns that may arise from
proposed and actual research. During the workshop, we will
describe potential conflicts of interest affecting: (1)
individual researchers, (2) institutions (hospitals and
universities), (3) research subjects/patients and (4) the
public at large, including the mass media. Short
presentations will set the stage for attendees to
participate in role playing with a variety of scenarios
and to present and discuss their own cases.
10:15am–11:45 am
6300—Early
Origins of Later Life Disease
PAS/LWPES
State of the Art
Chair: Sherin U. Devaskar,
University of California, Los Angeles, CA
This session will address the topic of "perinatal
origins of adult disease." The three speakers will
address different aspects related to the early origins of
adult disease. Dr. Kent Thornburg will address the issues
related to the fetal origins of adult-onset cardiovascular
disease, Dr. Guiseppe Colasurdo will discuss the impact on
adult-onset reactive airway disease due to postnatal
exposure to environmental stimulants, and Dr. Pinchas
Cohen will cover the influence of postnatal insulin-like
growth factor on the development of carcinogenesis. All
three speakers will shed light on the mechanisms
underlying the phenomenon of "Perinatal Origins of
Adult Disease" in three different disease states
using various animal models. This session will provide
cutting edge information that will help set the stage for
future interventions targeted at the mechanisms outlined.
Fetal Origins of Later-Life Cardiovascular Disease
Kent L. Thornburg, The Heart
Research Center, Oregon Health & Science University,
Portland, OR
Gene–Environment Interactions in Early Life and
Childhood Asthma: Search For Mechanisms
Giuseppe N. Colasurdo, University of
Texas-Houston Medical School, Houston, TX
The IGF System Through Development and Its Potential
Role in Carcinogenesis
Pinchas Cohen, Mattel Children's
Hospital at UCLA, Los Angeles, CA
Discussion
Sponsored jointly with the Lawson Wilkins Pediatric
Endocrine Society
10:15am–11:45 am
6301—Challenges
to Academic Medical Centers: Historical Perspectives and
Responses
PAS
State of the Art
Chair: Larry J. Shapiro,
University of California, San Francisco, CA
Academic Medical Centers (AMCs) are the result of
unique partnerships between medical schools, research
institutes, and teaching hospitals and are among the
treasures of our society. During the past century, AMCs
have evolved in response to need and opportunity as well
as to social and economic forces. They have made possible
unprecedented advances in human health, in biological
sciences, in medical technology, and in the education of a
very specialized and knowledgeable cadre of scientists,
physicians, and other health care professionals. In the
process, AMCs have grown large and ever more complex and
require continuous inputs of resources to sustain them.
Despite the apparent success of AMCs and their widely
appreciated intrinsic value, they are challenged as never
before. The diversity and complexity of missions has
created stresses upon the social order. Financial
pressures resulting from a fragmented, market driven
reimbursement system, lack of adequate attention to
preventive services and to cost of care issues, questions
about true measures of quality, ever more expensive
research infrastructure requirements, changing social
expectations combined with a relative illiteracy regarding
science and health in the general public threaten AMCs
existence as we know them. Despite fears that these
factors have the potential to create a "perfect
storm" that will derail the momentum for progress, a
detailed understanding of AMCs history, current
circumstances, and future prospects gives cause for
optimism. With thoughtful leadership, commitment to
values, and a willingness to lead change in many areas,
AMCs can continue to thrive and achieve even greater
success.
The speakers in this symposium are a practitioner of
medicine and historian who has written two very widely
read and highly acclaimed books about these issues,
Learning to Heal and Time to Heal (Kenneth Ludmerer) and a
former medical school clinician, teacher, investigator,
and dean who is now one of the nations most ardent and
eloquent spokespersons for AMCs in his role as president
of the Association of American Medical Colleges (Jordan
Cohen).
Overview
Larry J. Shapiro, University of
California, San Francisco, CA
Challenges to Academic Medical Centers: Evolution,
Nature and Potential Solutions
Kenneth M. Ludmerer, Washington
University, St. Louis, MO
21st Century Challenges for Academic Medical Centers
Jordan J. Cohen, Association of
American Medical Colleges, Washington, DC
Discussion
Supported by an educational grant from the Columbus
Children's Hospital
12:00pm–1:00pm
Poster
Session IV
Original
Science Abstracts – Poster Session
- General
- Health
Services Research
- Underserved
Populations
1:45pm–3:45 pm
6600—Dealing
with High-Risk Behavior in Adolescents: Current Concepts
of Solutions
PAS
Hot Topic
Chair: Donald E. Greydanus,
Michigan State University Kalamazoo Center for Medical
Studies, Kalamazoo, MI
This session examines specific solutions to high-risk
behavior in youth, beginning with an overview of current
epidemiologic issues. Principles of resilience in
adolescents are then examined, based on current research
data. Finally, principles of caring for gay and lesbian
youth are presented using an interactive approach with the
audience. The emphasis in this hot topic session is on
helping pediatric researchers and clinicians understand
what high-risk behavior in youth is and what research is
showing to be helpful.
Overview of High-Risk Behavior
Helen D. Pratt, Michigan State
University, Kalamazoo Center for Medical Studies,
Kalamazoo, MI
Concepts of Resilience
Michael D. Resnick, University of
Minnesota Gateway, Minneapolis, MN
Caring for Gay and Lesbian Youth
Ellen C. Perrin, The Floating
Hospital for Children, Tufts-New England Medical Center,
Boston, MA
Susan Starr, University of Massachussetts Medical School,
Worcester, MA
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