Gastroenterology and Nutrition

Last updated February 10, 2005

Saturday, MAY 14

8:00am–11:00am
4155—Institute of Medicine (IOM) Committee on Prevention of Obesity in Children and Youth: Recommendations and Assessment
PAS Educational Workshop
Leader: Thomas N. Robinson, Stanford, CA; Co-leaders: Dennis M. Bier, Vivica I. Kraak

The Institute of Medicine (IOM) Committee on Prevention of Obesity in Children and Youth is charged with assessing the nature of obesity in children and youth in the United States and developing a prevention-oriented action plan to reduce its prevalence. A summary of the report's findings and recommendations will be presented with a focus on public health approaches that promote energy balance by integrating diet and physical activity interventions at home, schools, medical care settings and in communities. Discussion and question-and-answer sessions with members of the Committee will address responses to the recommendations and public and policy reactions after the initial release. Participants will then create an individual action plan to advocate for their choices of specific recommendations.

Objectives:

1. Participants will become familiar with the concept of energy balance and be able to identify factors that contribute to obesogenic environments and promising public health approaches that support obesity prevention in children and youth.

2. Participants will develop a personal plan of action for implementing specific IOM recommendations when they return home from the meeting.

Method of Instruction: Brief presentation of highlighted IOM Committee results followed by (a) question-and-answer, (b) group discussion, and (c) development of action plans.

Target Audience: Trainee, junior faculty, mid-level faculty, senior faculty
 

11:45am–2:45pm
4506—Update in Neonatal/Pediatric Nutrition Support
PAS Mini Course
Chair: Michael Narkewicz, Children's Hospital, Denver, CO; and Mark Corkins, Riley Hospital for Children and Indiana University, Indianapolis, IN

Nutrition is critical to the normal growth and development of children. Our ability to supply nutrition to ill infants has increased dramatically in the last half of the twentieth century with the development of parenteral nutrition (TPN) and commercially prepared formulas. This advanced technology has also presented us with new knowledge as new nutritional deficiencies were discovered in patients on long-term TPN. The new technology has also created new risks associated with the supply of this nutrition. This session will explore some of the micronutrients necessary in infant TPN and some of the potential toxicities. The potential risks and new information concerning enteral formulas for use in infants will be presented.

Target Audience: Clinicians involved in the care of ill infants that require nutrition support beyond standard feedings.

Introduction
Michael R. Narkewicz, University of Colorado Health Sciences Center, Denver, CO

Cysteine, Choline and Carnitine: Are These Cs Important to the Neonate?
Sandeep K. Gupta, Riley Hospital for Children and Indiana University, Indianapolis, IN

Aluminum Toxicity in TPN
Gordon L. Klein, University of Texas Medical Branch, Galveston, TX

TPN-Associated Liver Disease in the Neonate
Beth Anne Carter, Baylor College of Medicine, Houston, TX

Fat Soluble Vitamin Requirements in the Neonate
Frank R. Greer, University of Wisconsin and Meriter Hospital, Madison, WI

Enteral Formula Safety
Mark R. Corkins, Riley Hospital for Children, Indiana University, Indianapolis, IN

Recent Advances in Neonatal Formulas
Jane D. Carver, University of South Florida College of Medicine, Tampa, FL

Discussion
 

11:45am–2:45pm
4572—Obesity
APA Special Interest Group
Chairs: Jennifer Bass, yenbass@aol.com; and Sandy Hassink, shassink@nemours.org

Implementing Obesity Prevention and Treatment—How To Translate What We Know into What Works

A panel discussion will lead off with short presentations of up and running obesity programs. Discussions will include clinic set up and structure, practical patient and family interventions, reimbursement issues and working in hospital and community settings. Attendees will be encouraged to share their own experiences and participate in discussion. The AHRQ video for pediatricians on obesity management will also be previewed and available to the audience.
 

3:15pm–5:15pm
4801—The Pediatric Generalist and Pediatric Subspecialists in the 21st Century: Who Will Take Care of Children with Subspecialty Disorders?
PAS Topic Symposium
Chair: Robert P. Schwartz, Wake Forest University School of Medicine, Winston-Salem, NC

The demand for pediatric subspecialty service is increasing, and waiting times for appointments get longer. Workforce and reimbursement issues contribute to the problem. In this symposium we will discuss the relationship of the pediatric generalist and subspecialist in the care of the children with common uncomplicated, as well as complex, subspecialty disorders in the 21st century.

Target Audience: Pediatric medical and surgical subspecialists, academic and private practice pediatricians.

Introduction and Opening Remarks
Robert P. Schwartz, Wake Forest University School of Medicine, Winston-Salem, NC

Role of the Pediatric Generalist in Management of Diabetes in the 21st Century
Francine R. Kaufman, University of Southern California Keck School of Medicine, Children's Hospital of Los Angeles, Los Angeles, CA

Role of the General Pediatrician in Management of Neurodevelopmental Disorders
Fan Tait, Utah Department of Health, Salt Lake City, UT

Role of the General Pediatrician in Management of Chronic Subspecialty Disorders
Gordon B. Glade, Utah Valley Pediatrics, American Fork, UT

Creating a Generalist-Specialist Team
Christopher J. Stille, University of Massachusetts Medical School, Worcester, MA

Discussion

Summary
Robert P. Schwartz, Wake Forest University School of Medicine, Winston-Salem, NC

Sponsored jointly by the American Academy of Pediatrics: Pediatrics for the 21st Century Symposium Series and the Pediatric Academic Societies
 

3:15pm–5:15pm
4843—Gastroenterology
PAS Original Science Abstracts - Platform Session

3:15pm–5:15pm
4847—Human Milk or Breastfeeding
PAS Original Science Abstracts - Poster Symposium

Sunday, MAY 15

8:00am–10:00am
5103—Gastroesophageal Reflux Disease in Infants and Children
PAS/NASPGHAN Topic Symposium
Chairs: Benny Kerzner, Children's National Medical Center, Washington, DC; and Eric Hassall, British Columbia Children’s Hospital, University of British Columbia, Vancouver, Canada

Moderate-to-severe GERD in the premature infant, newborn and child presents challenging diagnostic and therapeutic issues to a neonatologist, pediatrician, gastroenterologist and surgeon. First, new information on the epidemiology, pathophysiology and genetics will be presented. Second, new modes of diagnostic testing (e.g., impedance monitoring) will be reviewed along with extra-esophageal manifestations of GERD. Third, the pros and cons of medical, endoscopic (e.g., radiofrequency, ablation suturing) and surgical therapy will be discussed.

Target Audience: Scientists and clinicians involved with premature newborns, infants and children with difficult to manage moderate-to-severe reflux, suffering from extra-esophageal complications.

Overview
Eric Hassall, British Columbia Children’s Hospital, University of British Columbia, Vancouver, Canada

Born To Reflux: The Epidemiology, Pathophysiology and Genetic Features of GERD in Infants
Benny Kerzner, Children's National Medical Center, Washington, DC

EERD (Extraesophageal Reflux Disease): Reflux Beyond the Esophageal Box
Victor M. Pineiro, Nemours Children's Clinic-Orlando, FL

Too Many Operations, Too Few Reasons: Why it’s Time to Change Course
Eric Hassall, British Columbia Children’s Hospital, University of British Columbia, Vancouver, Canada

Sponsored jointly by the North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition and the Pediatric Academic Societies
 

8:00am–10:00am
5149—Underserved Populations I
PAS Original Science Abstracts - Platform Session

11:45am–1:45pm
Poster Session II
PAS Original Science Abstracts - Poster Session

Gastroenterology:
5450—Clinical
5451—Liver Disease
5452—Basic Science: Intestine
5453—Procedure-Based Research

Neonatology:
5468—Neonatal–Fetal Nutrition and Metabolism

12:00pm–1:30pm
5492A—Milk Club—Advancing Evidence-Based Care of Breastfeeding Mothers and Infants
 Club

Advancing Evidence-Based Care of Breastfeeding Mothers and Infants

Does Maternal Obesity Impede Lactation? Evidence and Clinical Implications
Kathleen M. Rasmussen, Cornell University, Ithaca, NY

Vitamin D Supplementation of Mothers or Infants? The Need for Evidence-Based Care
Carol L. Wagner, Medical University of South Carolina, Charleston, SC

Vitamin D and Breastfeeding Mother-Infant Pairs: An International Perspective
Adekunle H. Dawodu, Cincinnati Children's Hospital, Cincinnati, OH

The Milk Club gives one travel award each year to an outstanding trainee (medical, graduate, resident or post-doctoral student) who submits a first-authored abstract on breastfeeding.

Contact:
Ardythe L. Morrow, Ph.D.
Cincinnati Children's Hospital Medical Center
Phone: 513-636-7626
Email: ardythe.morrow@chmcc.org
 

2:00pm–4:00pm
5520—Consequences of Metabolic Syndrome in Children: Hypertension, Diabetes and Renal Disease
PAS/ASPN/IPHA/LWPES Topic Symposium
Chairs: Joseph Flynn, Montefiore Medical Center, Bronx, NY; and Henry Anhalt, Saint Barnabas Medical Center, Livingston, NJ

The incidence of the metabolic syndrome and of type 2 diabetes mellitus (T2DM) is now exploding in children as a consequence of the obesity epidemic. These children may be at significant risk of target-organ damage, including hypertension, atherosclerosis and diabetic nephropathy. This symposium will examine key aspects of this epidemic, with special focus on the pathogenesis of the target-organ effects of the metabolic syndrome in the young.

Target Audience: Any physician who cares for children with obesity, diabetes or their consequences—pediatricians, pediatric cardiologists, pediatric endocrinologists, pediatric nephrologists.

Can We Agree on a Definition of the Metabolic Syndrome in Children?
Sonia K. Caprio, Yale University School of Medicine, New Haven, CT

Pathogenesis of Structural Vascular Changes in Patients with Hypertension and the Metabolic Syndrome
Albert P. Rocchini, University of Michigan Health Center, Ann Arbor, MI

Diabetic Nephropathy in Patients with Type 1 and Type 2 Diabetes
Kumar Sharma, Jefferson Medical College, Philadelphia, PA

Mechanisms of Diabetic Nephropathy: Insights from Genomics/Proteomics
Erwin Bottinger, Mount Sinai School of Medicine, New York, NY

Sponsored jointly by the American Society of Pediatric Nephrology, International Pediatric Hypertension Association, Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies
 

2:00pm–4:00pm
5522—Update on Human Milk Immunobiology and Infectious Disease: New Insights and Current Controversies
PAS/PIDS/Milk Club Topic Symposium
Chairs: Mark R. Schleiss, University of Minnesota Medical School, Minneapolis, MN; and Lawrence M. Gartner, Professor Emeritus, University of Chicago, Chicago, IL

The importance of human milk feeding to reduce risk of infectious disease in infants is undisputed among pediatricians. Nevertheless, more data are needed about the basic biology of human milk, particularly in relation to specific health and developmental effects on term and premature infants. There have recently been significant advances in the understanding of the immunobiology of breast milk, particularly with respect to the role of oligosaccharides in protection against diarrheal disease, and new insights into interrelationships between breast milk and gut immune responses. In addition to presenting these new research data, this session will also review clinical controversies in breast feeding practice, including issues of milk storage and the potential for transmission of infectious pathogens, in particular cytomegalovirus, via human milk. Areas of need for future clinical and basic research will be emphasized.

Target Audience: Clinicians responsible for the care of newborn infants, particularly premature infants; neonatologists, gastroenterologists, infectious diseases physicians and general pediatricians; and basic scientists conducting research on human milk, secretory immunity or gut immunity.

The Future of Breast Milk Research: What Do We Need To Learn?
Lawrence M. Gartner, Professor Emeritus, University of Chicago, Chicago, IL

Human Milk Oligosaccharides and Their Role in Protection Against Gastroenteritis
Ardythe L. Morrow, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Infectious Diseases and Human Milk: Does Cytomegalovirus Pose a Risk to the Breast-fed Infant?
Mark R. Schleiss, University of Minnesota Medical School, Minneapolis, MN

Human Milk as a Carrier of Biochemical Responses to the Newborn
W. Allan Walker, Harvard Medical School, Boston, MA

Mother's Milk, Milk Banks and Preemies: Effects of Pasteurization and Storage on Milk Nutrition and Biology
Richard J. Schanler, Schneider Children's Hospital at North Shore, North Shore University Hospital, Manhasset, NY

Human Milk Immunology: The Whole Is Greater Than the Sum of Its Parts
Charles Isaacs, New York State Institute for Basic Research, Staten Island, NY

Discussion

Sponsored jointly by the Pediatric Infectious Diseases Society, the Milk Club and the Pediatric Academic Societies
 

2:00pm–4:00pm
5535—Neonatal Epidemiology and Follow-up
PAS Original Science Abstracts - Platform Session

2:00pm–4:00pm
5538—Pathogenesis, Prevention and Treatment of Necrotizing Enterocolitis
PAS Original Science Abstracts - Poster Symposium

2:00pm–5:00pm
5571—Childhood Obesity—Assessment, Surveillance and Intervention Within the School Setting
PAS Educational Workshop
Leader: Linda M. Grant, Boston, MA; Co-leaders: Anne McHugh, Sylvia Stevens-Edouard

This workshop will explore various strategies to address obesity in a school setting without competing with the prime educational mandate of teaching and learning. The pros and cons of conducting school-based obesity surveillance activities will be debated in a point–counterpoint forum that will highlight the challenges and offer solutions. Creative community partnerships to address school-based nutrition and fitness will be presented from several viewpoints, including that of a health insurance company and a school administrator.

Objectives:

1. Understand the supports needed to do school-based obesity surveillance activities.

2. Identify evidence-supported, school-based nutrition and fitness interventions and recognize collaborative partnership opportunities and the strategies to achieve them.

Method of Instruction: There will be point–counterpoint presentations by community partners to highlight issues from different vantage points followed by didactic that illustrates solutions.

Target Audience: Trainee, junior faculty, mid-level faculty, affiliate members.
 

2:00pm–5:00pm
5595—Proteomic Approaches to Diseases
SPR Special Interest Group
Chairs: James Schilling, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA; and Anne Murphy, Johns Hopkins University School of Medicine, Baltimore, MD

Proteomics is a rapidly evolving discipline that has the potential to provide insights into fundamental biology of disease and deliver clinically useful biomarkers. This session will focus on the application of different proteomic technologies in diverse diseases and demonstrate the impact proteomics can make.

Target Audience: Scientists and clinicians interested in using newly emerging proteomics methods for the elucidation of disease mechanisms and biomarker discovery.

Sponsored by the Society for Pediatric Research

Serum Proteomics and Biomarkers in Cardiovascular Diseases
Jennifer Van Eyk, Johns Hopkins School of Medicine, Bayview Proteomics Center, Baltimore, MD

Application of Proteomics to Cystic Fibrosis
Harvey B. Pollard, Uniform Health Services University, Bethesda, MD

Autoimmune Diseases and Protein Arrays
P.J. Utz, Stanford University Proteomics Center, Stanford, CA

Panel Discussion: Speakers and Session Chairs

Sponsored by the Society for Pediatric Research
 

4:15pm–6:15pm
5743—Pediatric Nutrition and Metabolism
PAS Original Science Abstracts - Platform Session

Monday, MAY 16

8:00am–10:00am
6140—Neonatal–Fetal Nutrition and Metabolism II
PAS Original Science Abstracts - Poster Symposium

8:00am–10:00am
6142—Obesity and Metabolism I
PAS Original Science Abstracts - Platform Session

9:00am–12:00pm
6202—Child and Adolescent Bariatrics: Merging Policy, Scholarship, Research and Advocacy
PAS Educational Workshop
Leader: Karen L. Young, Little Rock, AR; Co-leaders: Margaret Harris, Alba Morales, J. Darrell Nesmith, Pippa Simpson, Joseph W. Thompson, Wendy L. Ward-Begnoche, Judith L. Weber, J. Gary Wheeler

Child and adolescent bariatrics (the study of obesity) is a new area in pediatric medicine. The Arkansas experience with the BMI (Body Mass Index) Health Initiative will be presented to show how a statewide initiative can be a collaborative effort, coordinated with research and educational activities. This will serve to jumpstart discussions among the registrants and faculty:

1. Attendees will be given an opportunity to present experiences from their own community involvement and partnership development, specifically discussing how to effect translation of obesity research into policy, clinical care, education or advocacy.

2. Registrant groups will discuss research problems in childhood obesity including

a) how to create and manage databases for clinics or larger populations

b) ethical and psychological issues

c) starting an academic child and adolescent bariatrics center

d) research collaborations

e) policy and politics of obesity

Objectives:

1. Learn how to effect translation of obesity research into policy, clinical care, education and advocacy.

2. The learner will be able to discuss childhood obesity research problems, including creating a database, ethical issues, starting a new obesity center, collaboration, policy and politics.

Method of Instruction: Presentations by faculty, followed by short presentations by selected registrants, then roundtable discussions.

Target Audience: Trainee, junior faculty, mid-level faculty, senior faculty.
 

9:00am–12:00pm
6254—Nutrition
APA Special Interest Group
Chairs: Elizabeth Shepard, elizabeth.shepard@stanford.edu; and Robert J. Karp, robert.karp@downstate.edu

The Nutrition SIG is pleased to announce completion of its “Teacher’s Guide to Pediatric Clinical Nutrition.” It is easy to find at http://downstate.edu/peds/pednutrition. Or just go to the search bar at Google and type “pediatric nutrition and foliate” (or any other nutrient). Pediatric Nutrition Notes, the initial section of the Teacher’s Guide, comes up as the top entry.

The Teacher’s Guide uses the model of “stepping stone education.” The first section is a 44-page primer, Pediatric Nutrition Notes, providing the language of nutrition. The second is a set of introductions to assessing diet and behavior, assessing nutritional status, impact of food cost and culture and an overview of nutrition through the life cycle. The third section includes more than 25 case-based teaching modules on disease processes affected by nutrition.

Residents are invited to a two-hour program with continental breakfast to explore the Teacher’s Guide’s use in fulfilling two objectives of the Residency Review Committee: (1) teaching and (2) community outreach.

1. Training Teachers of Pediatrics: Residents will provide data illustrating use of the Teacher’s Guide in case conferences aids to improve learning and gain confidence and competence.

2. Reaching out to the Community: Residents will demonstrate use of four Teacher’s Guide modules adapted for community use enabling them to fulfill RRC requirement for community outreach.

Faculty and residents are invited to join us for presentations, discussion and continental breakfast. Registration is necessary. Email either robert.karp@downstate.edu or elizabeth.shepard@stanford.edu.
 

10:15am–12:15pm
6352—General Pediatrics II
PAS Original Science Abstracts - Platform Session

12:00pm–1:30pm
6410A—Perinatal Nutrition and Metabolism Club
 Club

Information not yet available.

Contact:
Jane McGowan, M.D.
The Johns Hopkins Hospital
Phone: 410-955-4565
Email: jmcgowan@jhmi.edu
 

2:00pm–4:00pm
6600—Virus–Host Interactions: Mechanisms Underlying Persistent Viral Infections
PAS/PIDS Topic Symposium
Chairs: Kenneth A. Alexander, Duke University Medical Center, Durham, NC; and John Vanchiere, Baylor College of Medicine, Houston, TX

In recent years it has become clear that traditional concepts about immune response to and clearance of pathogenic viruses are only part of the whole story. Increasing numbers of viruses are now recognized to cause persistent, low-level replication in the host, with long-term adverse health consequences in both normal and immune compromised hosts. These include viruses known to establish latency, such as the herpes viruses, and viruses that can cause persistent infection without a latent state, such as hepatitis C virus and polyomaviruses. This symposium will focus on virus–host interactions that allow for establishment of latent or persistent infection and the opportunities to exploit these interactions to facilitate gene therapy.

Target Audience: Scientists and clinicians from the following disciplines: pediatric infectious diseases, general pediatricians, pediatric gastroenterologists, pediatric hematology/oncology physicians.

Viral Persistence: Surveillance of the Iceberg from Its Surface
John A. Vanchiere, Baylor College of Medicine, Houston, TX

Unraveling the Molecular Mechanisms of Herpes Simplex Virus Latency and Reactivation in the Nervous System
Nancy M. Sawtell, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Hepatitis C: Mechanisms Contributing to Chronic Infection and Immune Evasion
Stanley Lemon, University of Texas Medical Branch, Galveston, TX

Adenovirus Based Vectors as Tools to Understand Viral Persistence
Andrea Amalfitano, Duke University Medical Center, Durham, NC

Sponsored jointly by the Pediatric Infectious Diseases Society and the Pediatric Academic Societies
 

3:00pm–5:00pm
6734—Obesity and Metabolism II
PAS Original Science Abstracts - Poster Symposium

5:15pm–6:45pm
Poster Session III
PAS Original Science Abstracts - Poster Session

Neonatology
6871—Gastroenterology, Nutrition, NEC
 

8:00am–10:00am
7102—Transitioning Complex Pediatric Patients to Adult Care
PAS/ASPN/LWPES Hot Topic
Chair: Sandra L. Watkins, University of Washington, Seattle, WA

Transitions are a part of everyone's life experience. Most young people with special health care needs and disabilities (SHCN/D) become independent members of adult society, but some need deliberate guidance and support. With increasing success in reducing the mortality of once devastating pediatric diseases, the latter group is growing in number. A new consensus statement from the American Academy of Pediatrics and the U.S. Federal Government (Healthy People 2010) has focused attention on the need to assist young people with SHCN/D in attaining their potential in adulthood. This symposium will discuss the growing number of young people with SHCN/D and present approaches for effecting these transitions.  Specific disease-related examples will be used to highlight the issues, the barriers and the key elements of successful programs that transition patients from pediatric care to the adult system.

All Grown Up and Wondering What To Do: Transitioning Complex Pediatric Patients to Adult Care
Patience H. White, George Washington University School of Medicine, Washington, DC

Transition Best Practices
Cecily L. Betz, University Center For Excellence in Development Disabilities, Children's Hospital Los Angeles, CA

Transition to Adult Care in the Nephrology Population–Renal Failure or Success
Maria Ferris, University of North Carolina-Chapel Hill, NC

Training and Workforce Issues for Successful Transition
Roberta G. Williams, University of Southern California, Los Angeles, CA

Discussion

Sponsored jointly by the American Society of Pediatric Nephrology, Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies
 

8:00am–10:00am
7152—Clinical Trials in Perinatal and Neonatal Medicine II
PAS Original Science Abstracts - Platform Session

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