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Saturday,
April 29
8:00am–11:00am
2120—Management
of Childhood Hypertension: Guidelines and Controversies
PAS/ASPN/IPHA
Mini Course
Chairs: Steven
R. Daniels, Cincinnati Children's Hospital Medical Center,
Cincinnati, OH; and Ronald J. Portman, University of Texas
Medical School, Houston, TX
Target
Audience: General pediatricians, emergency medicine
physicians, hospitalists, intensivists, nephrologists and
cardiologists.
The
2004 NHLBI guidelines for the evaluation and management of
childhood hypertension answered many questions about how to
approach hypertensive children, but left others unanswered.
This mini course is designed to address some of the more
controversial aspects of managing hypertensive children, with
the hope of stimulating further discussion about the optimal
approach to these patients. Practical approaches to clinical
management will be emphasized.
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Overview
Stephen
R. Daniels, Cincinnati Children's Hospital Medical Center,
Cincinnati, OH
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Overview
of Treatment Guidelines from the 4th Report
Bonita
E. Falkner, Thomas Jefferson University, Philadelphia, PA
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Management
of Pre-hypertension: Lifestyle Changes or Pharmacologic
Treatment?
Shawna
D. Nesbitt, University of Texas Southwestern Medical
Center, Dallas, TX
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Choice
of Agent for Children with Primary Hypertension
Joseph
T. Flynn, Children's Hospital at Montefiore, Bronx, NY
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Sponsored
jointly by the American Society of Pediatric Nephrology,
the International Pediatric Hypertension Association and
the Pediatric Academic Societies
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Treatment
of Severe Hypertension in Ambulatory and Inpatient
Settings
Joshua
Samuels, University of Texas, Houston, TX
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Treatment
of Hypertension in Special Populations
Donald
L. Batisky, Columbus Children's Hospital/The Ohio State
University College of Medicine, Columbus, OH
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Discussion
Sponsored
jointly by the American Society of Pediatric Nephrology, the
International Pediatric Hypertension Association and the
Pediatric Academic Societies
11:45am–2:45pm
2424—Treatment
of the Metabolic Syndrome in Children and Adolescents
PAS
Educational Workshop
Leader: J.
Darrell Nesmith, Little Rock, AR; Co-leaders: Alba Morales,
Mohammad Ilyas, Lisa Lubsch
Target
Audience: Endocrinologists, trainees, fellows, junior faculty,
mid-level faculty, senior faculty, and community
practitioners.
The
rise in pediatric obesity and metabolic syndrome is well
established. Less understood for the pediatrician is the
treatment of the metabolic syndrome. In this workshop, we aim
to: 1) briefly discuss the epidemiology of the metabolic
syndrome in children and adolescents, 2) discuss
non-pharmacologic and pharmacologic treatment of the metabolic
syndrome, and 3) review a stepped approach in treating
adolescents with the metabolic syndrome.
This
workshop will be largely case-based. Come prepared to devise
treatment plans in a small group setting. Participants are
invited to bring their own cases for discussion.
Objectives:
Participants
will:
–
Learn the epidemiology of the metabolic syndrome in children
and adolescents.
– Become familiar with existing treatment guidelines for
components of the metabolic syndrome in children and
adolescents.
– Identify gaps in the literature regarding treatment
guidelines of the metabolic syndrome in children and
adolescents.
– Consider pharmacologic treatment options of metabolic
syndrome treatment based on the available evidence.
1:00pm–3:00pm
2625—Nephrology
I
PAS/ASPN
Platform Session
3:15pm–5:15pm
2730—Mechanisms
of Hypertension in the Molecular Era
PAS/ASPN/IPHA/LWPES
Topic Symposium
Chairs: Bruce
Z. Morgenstern, Phoenix Children's Hospital, Phoenix, AZ; and
Julie R. Ingelfinger, Massachusetts General Hospital, Boston,
MA
Target
Audience: General pediatricians, nephrologists,
endocrinologists and neonatologists.
Our
understanding of the pathophysiology of hypertension has been
changing rapidly due to advances in molecular genetics, most
notably the identification of several single-gene defects that
cause hypertension. This session will update participants on
the latest advances in our knowledge of molecular mechanisms
of a variety of forms of hypertension.
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Role
of Dopamine Receptors
Pedro
A. Jose, Georgetown University Medical Center, Washington,
DC
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Perinatal
Programming and the Development of Hypertension
Lori
Woods, Oregon Health & Science University, Portland,
OR
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Low
Renin Hypertension in Childhood
Maria
I. New, Mount Sinai School of Medicine, New York, NY
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WNK
Kinases and Blood Pressure Regulation
Richard
Lifton, Yale University School of Medicine, New Haven, CT
Sponsored
jointly by the American Society of Pediatric Nephrology, the
International Pediatric Hypertension Association, the Lawson
Wilkins Pediatric Endocrine Society and the Pediatric Academic
Societies
5:15pm–6:00pm
2800—Clinical
Pediatric Hypertension
PAS/ASPN/IPHA
Original Science Abstracts - Poster Symposium
Sunday,
April 30
7:00am–8:00am
IPHA
Business Meeting
All current
IPHA members as well as other interested individuals are
invited to join us for discussion of current and upcoming IPHA
activities. Continental
breakfast will be served.
8:00am–11:00am
3256
Obesity
APA Special Interest Group
Pacific Suite I, SF Marriott
Treatment
of Childhood Obesity: A Case-Based Approach
A panel of
obesity clinicians will address the practical aspects of
obesity treatment in a clinical case-based approach. A variety
of clinical scenarios and vignettes will be presented for
discussion, with opportunities for role playing and audience
participation. The cases will cover issues relating to
childhood overweight and obesity for a variety of ages and
developmental stages. Some of the issues included will be
readiness for change, behavior modification and other
strategies, medications and screening and treatment of
co-morbid conditions.
Monday,
May 1
8:00am–11:00am
4150—The
Skinny on the Adipocyte
PAS/LWPES
Mini Course
Chairs: Silva
A. Arslanian, University of Pittsburgh, Pittsburgh, PA; and
Robert H. Lustig, University of California, San Francisco, CA
Target
Audience: General pediatricians, gastroenterologists,
endocrinologists, cardiologists, pulmonologists and adolescent
medicine specialists.
Over
the past five years much has been learned about the adipocyte.
The ability of the adipocyte to function as an endocrine
gland, elaborating inflammatory cytokines that result in free
radical formation and premature apoptosis of the beta cell, is
a relatively new concept. This mini course will
comprehensively address many of the newest concepts in
adipocyte function and their impact on health and disease.
Further discussion will include new concepts on the
interactions of IGF-II and other peptides' interactions with
the adipocyte. Lastly, there will be a call for new approaches
to the pediatric obesity epidemic.
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Adipose
Tissue as an Endocrine Organ
Susan
Fried, University of Maryland School of Medicine,
Baltimore VA Medical Center, Baltimore, MD
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Obesity
and Inflammation
Christopher
Hug, Whitehead Institute and Children's Hospital,
Cambridge, MA
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Effects
of GH, IGF-I and Insulin Therapies on Adiposity
Zvi
Laron, Schneider Children's Medical Center of Israel,
Petah Tikva, Isreal
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Pathology
and Sequelae of Childhood Obesity in Adult Life
Dennis
M. Styne, University of California, Davis Medical Center,
Sacramento, CA
Sponsored
jointly by the Lawson Wilkins Pediatric Endocrine Society and
the Pediatric Academic Societies
5:15pm–6:45pm
Poster Session III
PAS
Original Science Abstracts
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