2006 PAS Annual Meeting

April 29–May 2 
San Francisco, California

LWPES Daily Schedule 

 
Friday, April 28

6:00pm–8:00pm
1700A—LWPES Welcome Reception
LWPES Reception

Sponsored by the Lawson Wilkins Pediatric Endocrine Society

Saturday, April 29

8:00am–11:00am
2155—Gender-Variant Youth: The Role of the Pediatrician
PAS Educational Workshop
Leader: Irene Sills, Albany, NY; Co-leader: Arlene Lev

Target Audience: Trainees, fellows, junior faculty, mid-level faculty, senior faculty, and community practitioners.

This workshop is an overview of sexual and gender identity development in children and youth focusing on understanding the needs of transgender and transsexual youth. By review of case presentations, attendees will gain skills and knowledge in how to assist parents of children with gender variant behavior, children with gender identity confusion, and adolescents who exhibit cross-gender behaviors. Ethical considerations in the care of this population will be presented and discussed. Current standards for hormonal therapy will be reviewed.

Objectives:

– The participant will demonstrate an understanding of the developmental appropriateness of youth with gender variant behavior.
– The participant will prepare to assist children and adolescents with gender variant behavior and their families.
– The participant will demonstrate an understanding of the ethical issues in the medical care of transgendered adolescents.

8:00am–12:00pm
2180A—LWPES Plenary Session I
LWPES Plenary Session
Chairs: Lynne Levitsky, Massachusetts General Hospital, Boston, MA; Henry Anhalt, Saint Barnabas Medical Center, Livingston, NJ; and Alan D. Rogol, University of Virginia, Charlottesville, VA

Target Audience: Endocrinologists, nephrologists, cardiologists, general pediatricians, immunologists, geneticists and molecular biologists.

• Opening Remarks
  Lynne L. Levitsky, Massachusetts General Hospital, Boston, MA
• Lawson Wilkins Lecture:
  Recent years have witnessed a significant revision of the traditional view of fat cells as simple stores of excess energy. Studies in the speakers lab as many others, have clearly demonstrated that adipocytes produce and regulate many metabolic and hormonal signals, which generate profound effects on systemic endocrine equilibrium. In his earlier studies,he has also demonstrated that these cells exhibit an inflammatory capacity which is abnormal in obesity and key to the pathogenesis of insulin resistance and diabetes. Recently, he identified a key molecular mechanism underlying the link between inflammatory responses and insulin action. This pathway involves obesity-related activation of the serine.threonine kinase, JNK, and the consequent inhibition of insulin receptor signaling via phosphorylation of a substrate of insulin receptor, IRS-1.
  • Integration of Metabolic and Inflammatory Pathways in Metabolic Disease
    Gokhan S. Hotamisligil, Harvard School of Public Health, Boston, MA
• Robert Blizzard Lecture:
  One of the greatest questions asked of physicians caring for children with autoimmune diabetes is "why did this happen?" This session will unravel some of the mysteries surrounding the etiology and pathogenesis of autoimmune diabetes from an investigator who has dedicated his life to this issue.
  • On the Unravelling—The Etiopathogenesis of Type 1 Diabetes: Are We Stuck, or Are We Winning?
    Gian Franco Bottazzo, Ospedale Pediatrico Bambino Gesú, Scientific Institute, Rome, Italy
• Break
• Esoterix Lecture:
  The attendee will familiarize him/herself with newer molecular mechanisms of growth failure that are due to abnormalities in receptor and post-receptor translation of GH signaling.
  • Molecular Mechanisms and Defects in Growth Hormone Receptor Signaling
    Peter Rotwein, Oregon Health and Science University, Portland, OR

1:30pm–3:30pm
2670A—Controversies in Care in Pediatric Endocrinology—The Great Debates
LWPES Workshop
Chairs: William Clarke, University of Virginia, Charlottesville, VA; and Henry Anhalt, St. Barnabas Medical Center, Livingston, NJ

Target Audience: Endocrinologists, general pediatricians and adolescent medicine specialists.

The attendee will be part of a lively debate on a number of areas of controversy in pediatric state-of-the-art diabetes management.

• Is Primary Prevention of Type 1 Diabetes Possible?
  Pro—Desmond A. Schatz, University of Florida, Gainesville, FL
  Con—Dorothy J. Becker, Children's Hospital of Pittsburgh, Pittsburgh, PA

• Should Glucose Sensors Be Routinely Used?
  Pro—Stuart Alan Weinzimer, Yale School of Medicine, New Haven, CT
  Con—Darrell M. Wilson, Stanford University Medical Center, Stanford, CA

• Should Metformin Be Used To Treat Pediatric Patients with Insulin Resistance?
  Pro—Michael S. Freemark, Duke University Medical Center, Durham, NC
  Con—Philip Scott Zeitler, University of Colorado at Denver and Health Sciences Center, Denver, CO

1:30pm–3:30pm
2675A—Controversies in the Management of Non-classical Congenital Adrenal Hyperplasia
LWPES Workshop
Chairs: Perrin White, University of Texas Southwestern Medical Center, Dallas, TX; and Ieuan Hughes, University of Cambridge, Cambridge, UK

Target Audience: Neonatologists, endocrinologists, generalists and adolescent medicine specialists.

Non-classical adrenal hyperplasia (NCAH) occurs more commonly than does the classical form and may masquerade as hirsutism, acne and menstrual cycle dysfunction. NCAH must be considered in the differential diagnosis of these relatively common conditions. The diagnosis of NCAH is being made more frequently today as a result of greater access to genotyping available through many commercial laboratories. Once the diagnosis is made, however, the controversies begin. Who should have stress-dose glucocorticoids and who should have prenatal screening are some of the controversial issues.

• Glucocorticoid Coverage and Treatment in Non-classical Adrenal Hyperplasia
  Mitchell E. Geffner, Children's Hospital Los Angeles, Los Angeles, CA

• Role or No Role of Prenatal Diagnosis and Newborn Screening in Non-classical Adrenal Hyperplasia
  Patricia A. Donohoue, The Children's Hospital of Iowa at the University of Iowa Hospitals and Clinics, Iowa City, IA

• Fertility in Patients with Non-classical Adrenal Hyperplasia
  Marcelle Cedars, University of California-San Francisco, San Francisco, CA

2:15pm–5:15pm
2705—Vitamin D: More Than Just Calcium and Bone
PAS/LWPES Mini Course
Chairs: Catherine M. Gordon, Children's Hospital of Boston, Boston, MA; and Linda A. DiMeglio, Indiana University, Indianapolis, IN

Target Audience: General pediatricians, gastroenterologists, endocrinologists and hematologists/oncologists.

The understanding of the role of vitamin D in health and illness is becoming more complex. Both skeletal and extra-skeletal actions have been described, and vitamin D analogs are being explored for their anti-proliferative effects. The attendee will gain both clinically relevant epidemiological knowledge as well as review the calcemic and non-calcemic actions of Vitamin D.

• What Is the Evidence for Vitamin D Deficiency in Children?
  Frank R. Greer, University of Wisconsin, Madison, WI

• Vitamin D and Extra-Skeletal Actions in Health
  Michael F. Holick, Boston University School of Medicine, Boston, MA

• Non-calcemic Actions of Vitamin D Receptor Ligands
  Sunil Nagpal, Eli Lilly Research Laboratories

Sponsored jointly by the Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies

3:15pm–5:15pm
2730—Mechanisms of Hypertension in the Molecular Era
PAS/ASPN/IPHA/LWPES Topic Symposium
Chairs: Bruce Z. Morgenstern, Phoenix Children's Hospital, Phoenix, AZ; and Julie R. Ingelfinger, Massachusetts General Hospital, Boston, MA

Target Audience: General pediatricians, nephrologists, endocrinologists and neonatologists.

Our understanding of the pathophysiology of hypertension has been changing rapidly due to advances in molecular biology, most notably the identification of several single-gene defects that cause hypertension. This session will update the audience on the latest advances in our knowledge of molecular mechanisms of a variety of forms of hypertension.

• Role of Dopamine Receptors
  Pedro A. Jose, Georgetown University Medical Center, Washington, DC

• Perinatal Programming and the Development of Hypertension
  Lori Woods, Oregon Health & Science University, Portland, OR

• Low Renin Hypertension in Childhood
  Maria I. New, Mount Sinai School of Medicine, New York, NY

• WNK Kinases and Blood Pressure Regulation
  Richard Lifton, Yale University School of Medicine, New Haven, CT

Sponsored jointly by the American Society of Pediatric Nephrology, the International Pediatric Hypertension Association, the Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies

3:45pm–5:15pm
2785A—Celiac Disease for the Non-gastroenterologist
LWPES Workshop
Chair: Michelle M. Pietzak, Children's Hospital of Los Angeles, Los Angeles, CA

Target Audience: Gastroenterologists and endocrinologists.

Celiac disease affects approximately 10-15% of children with diabetes. Often times the screening tests are vexing. This workshop is aimed at clarifying the disease process and how to diagnose it.

3:45pm–5:15pm
2790A—Hyperthyroidism
LWPES Workshop
Chair: Scott A. Rivkees, Yale School of Medicine, New Haven, CT

Target Audience: Generalists.

Much controversy exists about the most effective and safest treatments for hyperthyroidism in children. This workshop will clarify some of the newer evidence based approaches to the diagnosis and management of hyperthyroidism, with a special emphasis on radioactive ablation.

3:45pm–5:15pm
2795A—Neonatal Diabetes
LWPES Workshop
Chair: Mark A. Sperling, Children's Hospital of Pittsburgh, Pittsburgh, PA

Target Audience: Endocrinologists and neonatologists.

Over the past few years much has been learned about the pathogenesis of neonatal diabetes. This workshop will impart knowledge on important considerations in the diagnosis and work-up of this rare condition.

Sunday, April 30

7:45am–9:00am
3080A—LWPES Business Meeting
LWPES Business Meeting

8:00am–10:00am
3125—Developmental Origins of Adult Disease—Metabolism
PAS Platform Session

9:00am–10:00am
3290A—LWPES Presidential Lecture
LWPES Presidential Plenary
Chair: Alan D. Rogol, University of Virginia, Charlottesville, VA

• Pediatric Endocrinology Past and Present: Are We Ready for the Future?
  Lynne L. Levitsky, Massachusetts General Hospital, Boston, MA

10:00am–11:45am
3325A—Endocrinology/Diabetes Awards
LWPES Platform Session

• LWPES Clinical Scholars Presentations

2:00pm–4:00pm
3710—Non-Growth Related Issues in Girls with Turner Syndrome
PAS/LWPES Topic Symposium
Chairs: Judith G. Hall, The University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada; and Paul H. Saenger, Montefiore Medical Center, The Bronx, NY

Target Audience: Geneticists, endocrinologists, cardiologists and, developmental pediatricians.

Although the focus of the pediatric endocrine community has been primarily on the growth issues of girls with Turner Syndrome, other non-growth issues continue to be described. This topic symposium will highlight these non-growth-related issues and illuminate the problems and strategies of dealing with them.

• Evaluation of Congenital and Acquired Heart Disease in Turner Syndrome
  Carolyn A. Bondy, National Institute of Child Health and Human Development, Bethesda, MD

• Skeletal Health
  Vladamir K. Bakalov, National Institute of Child Health and Human Development, Bethesda, MD

• Non-verbal Learning Disabilities
  Marsha L. Davenport, University of North Carolina at Chapel Hill, Chapel Hill, NC

Sponsored jointly by the Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies

2:00pm–5:00pm
3750—Endocrine Disrupters
PAS/LWPES Mini Course
Chairs: Mary M. Lee, University of Massachusetts Medical School, Worcester, MA; and Henry Anhalt, Saint Barnabas Medical Center, Livingston, NJ

Target Audience: Endocrinologists, generalists, neonatologists and basic scientists.

Concerns regarding clinical consequences of endocrine disrupting chemicals have increased over the past decade as researchers have documented detrimental effects in wildlife. Federal attention to endocrine disrupters began in earnest in 1996 when the U.S. Congress passed the Food Quality Protection Act and amended the Safe Drinking Water Act. These laws mandated testing to determine if pesticides and industrial chemicals might behave like hormones; therefore, the U.S. EPA formed the Endocrine Disrupters Screening and Advisory Committee. In addition to direct effects, some environmental disrupters act through non-genomic actions, some of which persist for several generations. This program presenting innovative studies on mechanisms of action of endocrine disruptors will be of critical interest to endocrinologists, both clinical and basic scientists, as well as public health experts.

• Prenatal Programming with Estrogen/Estrogen Mimetics
  Kenneth S. Korach, National Institute of Environmental Health Sciences, Research Triangle Park, NC

• Epigenetic Transgenerational Actions of Endocrine Disruptors on Male Fertility and Other Diseases
  Michael K. Skinner, Washington State University, Pullman, WA

• Prenatal Programming with Native and Environmental Steroids
  Vasantha Padmanabhan, University of Michigan, Ann Arbor, MI

Sponsored jointly by the Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies

4:15pm–6:15pm
3845—Endocrinology: Insulin Resistance/Obesity
PAS/LWPES Poster Symposium

Monday, May 4

8:00am–10:00am
4110—Pediatric Fluids and Hyponatremia: Are We Giving Too Much Water?
PAS/ASPN/LWPES Topic Symposium
Chairs: John W. Foreman, Duke University Medical Center, Durham, NC; and D. Michael Foulds, University of Texas Health Science Center at San Antonio, San Antonio, TX

Target Audience: Nephrologists, general pediatricians, emergency room doctors, intensivists, hospitalists, endocrinologists and anyone who administers IV maintenance fluids.

In the 1950s, Holiday and Segar devised formulae for calculating intravenous maintenance fluids for infants and children who were unable to drink. These formulae have been taught and used now for over 40 years and have generally stood the test of time. However, several recent investigators have challenged these formulae and argued that they put children at risk of hyponatremia. Since Holiday and Segar devised these formulae, new information has arisen, such as the concept of non-osmotic stimulation of ADH release in sick children and our ability to measure ADH levels in plasma on a routine basis. Arieff and Ayus were the first to point out that children and women are at particular risk for developing hyponatremic encephalopathy. Moritz and Ayus have subsequently argued that hypotonic parenteral fluid should not be used unless there are ongoing free water losses or hypernatremia. In addition to this new clinical data, Verkman’s group has exciting data identifying molecular mechanisms of cerebral edema, including after water intoxication. Dr. Arieff will review who is at risk and why. Dr. Verkman’s group has developed data regarding mechanisms of cerebral edema in experimental animals. Dr. Moritz will describe the new concepts of maintenance fluids. Dr. Friedman will defend the current practice. At the end there will be time for an exchange between the speakers and the audience on the right fluid to use in today’s children.

• Hyponatremic Encephalopathy: Special Risk Factors for Children and Women
  Allen I. Arieff, University of California San Francisco, San Francisco, CA

• Aquaporin 4 and Cerebral Edema
  Alan S. Verkman, University of California San Francisco, San Francisco, CA

• 0.9% Sodium Chloride: The New Approach to Maintenance Fluids in Pediatrics
  Michael L. Moritz, Children's Hospital of Pittsburgh, Pittsburgh, PA

• Maintenance Therapy: Tried and True
  Aaron L. Friedman, Brown Medical School, Hasbro Children's Hospital, Providence, RI

Sponsored jointly by the AAP Section on Nephrology, the American Society of Pediatric Nephrology, the Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies

8:00am–11:00am
4150—The Skinny on the Adipocyte
PAS/LWPES Mini Course
Chairs: Silva A. Arslanian, University of Pittsburgh, Pittsburgh, PA; and Robert H. Lustig, University of California, San Francisco, CA

Target Audience: General pediatricians, gastroenterologists, endocrinologists, cardiologists, pulmonologists and adolescent medicine specialists.

Over the past five years much has been learned about the adipocyte. The ability of the adipocyte to function as an endocrine gland, elaborating inflammatory cytokines that result in free radical formation and premature apoptosis of the beta cell, is a relatively new concept. This mini course will comprehensively address many of the newest concepts in adipocyte function and their impact on health and disease. Further discussion will include new concepts on the interactions of IGF-II and other peptides' interactions with the adipocyte. Lastly, there will be a call for new approaches to the pediatric obesity epidemic.

• Adipose Tissue as an Endocrine Organ
  Susan Fried, University of Maryland School of Medicine, Baltimore VA Medical Center, Baltimore, MD

• Obesity and Inflammation
  Christopher Hug, Whitehead Institute and Children's Hospital, Cambridge, MA

• Effects of GH, IGF-I and Insulin Therapies on Adiposity
  Zvi Laron, Schneider Children's Medical Center of Israel, Petah Tikva, Isreal

• Pathology and Sequelae of Childhood Obesity in Adult Life
  Dennis M. Styne, University of California, Davis Medical Center, Sacramento, CA

Sponsored jointly by the Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies

10:15am–12:15pm
4320A—New Frontiers in Reproductive Science
LWPES Topic Symposium
Chairs: Ram K. Menon, University of Michigan, Ann Arbor, MI; and Henry Anhalt, Saint Barnabas Medical Center, Livingston, NJ

Target Audience: Endocrinologists, geneticists, developmental biologists and adolescent medicine.

The regulation of puberty remains one of the greatest mysteries of medicine. A child is born with all of the necessary components to undergo puberty at birth but this process is quiescent until puberty occurs. The attendee will learn the newest information on the biological regulators of puberty.

In addition, the attendee will be exposed to newer techniques available for preservation of fertility in a variety of different pathological states. Discussion will include the cryopreservation of the pre-pubertal ovary.

• Kiss-1 and GPR54 as New Players in Gonadotropin Regulation and Puberty
  Ursula Kaiser, Brigham and Women's Hospital, Boston, MA

• Modern Preservation of Fertility
  Kutluk Oktay, Weill Medical College of Cornell University, New York, NY

10:15am–12:15pm
4330—Endocrinology: Growth—Clinical
PAS/LWPES Platform Session

1:00pm–2:45pm
4500   March of Dimes Prize in Developmental Biology Lecture

Dr. Varshavsky is a pioneer in the study of ubiquitin, a tiny protein that has a very big job. Ubiquitin (from the Latin ubique meaning "everywhere," the source of the word "ubiquitous") is so named because it is essential to nearly every major activity in the life cycle of cells, including cell growth and division during embryo development, DNA repair, programmed cell death, immune response, and the nervous system. The ubiquitin system is the housekeeping mechanism by which the cell maintains a proper and healthy balance of proteins. Ubiquitin's role was unknown until the 1980s, when Dr. Varshavsky and colleagues elucidated it. This discovery revolutionized our understanding of the control of human cells, and ubiquitin quickly became one of the major areas of study in genetics, developmental biology, cell biology, and biochemistry. Today ubiquitin is a cornerstone of medical research into the causes and treatments of birth defects, neurodegenerative disease, infections, and cancer. Dr. Varshavsky receives the 2006 March of Dimes Prize for revealing and characterizing the biological significance of the ubiquitin system in the regulation of living cells.

• Regulation by Proteolysis:  The N-End Rule Pathway in Yeast and Mammals
  Alexander Varshavsky, Smits Professor of Cell Biology, California Institute of Technology, Pasadena, CA

Presented by the March of Dimes Birth Defects Foundation

3:00pm–4:00pm
4600A—LWPES Trans-Pacific Lecture
LWPES Award
Chair: Mark Sperling, Children's Hospital of Pittsburgh, Pittsburgh, PA

Target Audience: Geneticists, endocrinologists and molecular biologists.

This new lecture recognizes one outstanding scientist from the Pacific Rim. This talk will illuminate congenital adrenal disorders with particular focus on the relationship between newborn screening and molecular mechanisms.

Congenital Adrenal Disorders: From Newborn Screening to Molecular Mechanism
Kenji Fujieda, Asahikawa Medical College, Asahikawa, Japan

3:00pm–5:00pm
4675—Obesity I
PAS Poster Symposium

Tuesday, May 2

8:00am–10:00am
5158—Endocrinology: Diabetes—Immune Mediated
PAS Poster Symposium

8:30am–9:45am
5200A—The Challenge of Diagnosis and Outcome in Intersex
LWPES State of the Art Plenary
Chair: Lynne Levitsky, Massachusetts General Hospital, Boston, MA

Target Audience: Geneticists, endocrinologists and general pediatricians.

The attendee will be presented with an overview of intersex and then the challenges of diagnosis and outcome will be addressed. Many previous assumptions about outcome have proven to be false. This should prove to be an exciting talk about a highly controversial topic affecting pediatric endocrinologists and geneticists.

• The Challenge of Diagnosis and Outcome in Intersex
  Ieuan Hughes, University of Cambridge, Cambridge, UK

10:00am–11:45am
5300A—Late-Breaking Clinical Trials
LWPES Workshop
Chairs: Mitchell Geffner, Children's Hospital of Los Angeles, Los Angeles, CA; and Lawrence Silverman, Goryeb Children's Hospital Morristown, Morristown, NJ

Target Audience: Pediatric endocrinologists, fellows, trainees and geneticists.

This session will allow investigators of major multi-center national trials being conducted in the United States to share their late-breaking data with the pediatric community at large. This session will have particular appeal for trainees and junior faculty.

• Trial Net
  Desmond A. Schatz, University of Florida, Gainesville, FL

• STOPPT2D
  Francine R. Kaufman, Children's Hospital of Los Angeles, Los Angeles, CA

• Histrelin Implant Study in Children with Central Precocious Puberty
  Erica A. Eugster, Indiana University, Indianapolis, IN

• Toddler Turner Trial
  Marsha L. Davenport, University of North Carolina at Chapel Hill, Chapel Hill, NC

• IGF-I Deficiency and Treatment Using IGF-Based GH Dosing
  Pinchas Cohen, Mattel Children's Hospital at UCLA, Los Angeles, CA

• Discussion

10:00am–11:45am
5310A—Pitfalls in Endocrine Assays—Results Are Not What They Seem
LWPES Workshop
Chairs: Jack Fuqua, Indiana University, Indianapolis, IN; and John Nakamoto, Quest Diagnostics, San Juan Capistrano, CA

Target Audience: Endocrinologists, general pediatricians and adolescent medicine.

All too often clinicians are encountering laboratory tests that are difficult to interpret. Sometimes the real problem lies in understanding the pitfalls in assays and how they are performed. This symposium will help the clinician and scientist understand the basis for assays and what can go wrong with them. Many referrals to subspecialists are made due to misinterpretation of laboratory tests or unfamiliarity with age related norms. This symposium will have wide appeal to all who order endocrine tests.

• Overview
  Jon M. Nakamoto, Quest Diagnostics, San Juan Capistrano, CA

• IGF–I/GH
  George M. Bright, Tercica, Inc., South San Francisco, CA

• Adrenal Steroids and Thyroid
  Jon M. Nakamoto, Quest Diagnostics, San Juan Capistrano, CA

• Sex Steroids
  Dennis M. Styne, University of California, Davis Medical Center, Sacramento, CA

• Discussion

10:15am–12:15pm
5430—Obesity II
PAS Platform Session

10:15am–12:15pm
5435—Endocrinology and Diabetes—Basic Research
PAS/LWPES Platform Session

1:45pm–3:45pm
5730—Obesity Symposium—The BIG Picture
PAS/LWPES Hot Topic
Chairs: Janet H. Silverstein, University of Florida College of Medicine, Gainesville, FL; and Josephine Z. Kasa-Vubu, University of Michigan, Ann Arbor, MI

Target Audience: General pediatrics, developmental pediatrics, adolescent medicine, genetics, basic science, pediatric endocrinology and health outcomes.

The obesity epidemic continues to be a major public health threat and a top priority for a broad range of researchers and clinicians. This symposium will attempt to reach beyond descriptive statistics and will focus on advances from bench to bedside with a focus on intervention.

• Overview
  Josephine Z. Kasa-Vubu, University of Michigan, Ann Arbor, MI

• Lessons from the Bench: Molecular and Anatomical Models of Leptin Resistance
  Martin Myers, University of Michigan, Ann Arbor, MI

• Intensive Versus Behavior Therapies for the Obese Child: What We Know and What We Do Not Know
  Jack Adam Yanovski, National Institutes of Health, Bethesda, MD

• Long-Term Costs of Early Onset Diabetes
  William H. Herman, University of Michigan Medical School and School of Public Health, Ann Arbor, MI

• Prenatal Programming of Obesity and Obesity-Related Behaviors
  Peter D. Gluckman, Liggins Institute, University of Auckland, Auckland, New Zealand

• Discussion

Sponsored jointly by the Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies

Additional PAS Programming of Interest

Saturday, April 29

600am–8:00am
Diagnosis, Treatment and Cost Analysis of Growth Hormone Deficiency
PAS Industry Sponsored Symposium

8:00am–11:00am
2100—Adult Stem Cells—A Primer for the Clinician
PAS/ASPHO Mini Course

8:00am–11:00am
2125—New Considerations for the Growth Rate of the Preterm Infant: Too Fast or Not Fast Enough?—A Review of the Evidence
PAS Mini Course

11:45am–2:45pm
2424—Treatment of the Metabolic Syndrome in Children and Adolescents
PAS Educational Workshop

12:00pm–3:00pm
2505—Embryonic Stem Cells: A Primer for Clinicians
PAS Mini Course

5:15pm–6:00pm
2800—Clinical Pediatric Hypertension
PAS/IPHA/ASPN Poster Symposium

7:00pm–9:00pm
Practical and Scientific Approaches to Growth Hormone: From Pediatrics to Adults
PAS Industry Sponsored Symposia

Sunday, April 30

4:15pm–5:45pm
3805—Fetal Homeland Security: New Insights into Old Threats
PAS State of the Art Plenary

4:15pm–5:45pm
3810—RNA Interference, Technological Development of siRNAs and Potential Treatments for Childhood Diseases
PAS State of the Art Plenary

4:15pm–6:15pm
3850—Human Milk and Breastfeeding
PAS Poster Symposium

Tuesday, May 2

8:00am–10:00am
5110A—Inflammation in Uremic Pathophysiology
ASPN Symposium