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Saturday, April 29
8:00am–11:00am
2130—Newborn Hearing Screening: From the
Bedside to Beyond
PAS/PIDS Mini Course
Room 3010, Moscone West
Chairs: Mark R. Schleiss and Lisa Ann Schimmenti, University
of Minnesota Medical School, Minneapolis, MN
Target Audience: General
pediatricians, geneticists and infectious disease specialists.
Sensorineural hearing loss (SNHL)
in infants is the most common birth defect, and early
detection improves outcome. Evidence from the CDC reveals that
less than one half of screened babies are followed up. One
possible reason is the low positive predictive value of
bedside screening. There is a critical need to augment current
strategies to prevent late diagnosis of SNHL. One solution is
to propose second-tier testing for the most common causes of
SNHL, as the most common causes of newborn hearing loss are
infectious and genetic. Of infectious causes, cytomegalovirus
(CMV) is the most common. Evidence of CMV infection can be
found in 1% of newborns, with 10–15% developing hearing loss
or other CNS abnormalities. Of the genetic causes, mutations
in GJB2/GJB6 are the most common and are identified in up to
one half of individuals with SNHL. The goal of this program
will be to examine evidence for inclusion of infectious and
genetic screening to augment current newborn screening
protocols.
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Diagnostic Evaluation and
Management of Childhood Hearing Loss
Margaret Alene Kenna, Children's Hospital Boston, Boston, MA
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Range of Mutations in
GJB2-Associated Hearing Loss
Lisa Ann Schimmenti, University of Minnesota Medical School,
Minneapolis, MN
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Congenital Cytomegalovirus
Infection and Hearing Loss
Karen B. Fowler, University of Alabama at Birmingham, Birmingham, AL
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Newborn Hearing Screening:
Audiologic Assessment
Yvonne Sininger, University of California Los Angeles, Los Angeles, CA
Sponsored jointly by
the Pediatric Infectious Diseases Society and the Pediatric
Academic Societies
11:45am–2:45pm
2406—Enhancing Efficiency and Productivity
in the Patient Care Environment with the Use of Personal
Digital Assistants (PDAs)
PAS Educational Workshop
Golden Gate Hall C2, SF Marriott
Leader: Srinivasan Suresh, Detroit, MI; Co-leaders: Anne
Mortensen, Kate Sheppard
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty, and senior
faculty.
A potentially compelling
environment for the use of Personal Digital Assistants (PDA)
exists in most hospitals. This workshop will demonstrate
effectively using the Pocket PC PDA in facilitating resident
education, bedside clinical teaching, and patient care,
sign-out and communication in the aftermath of the 80-hour
week, and improving the cost effectiveness of wireless
networks in the patient care setting.
A hands-on workshop component
will demonstrate how these handheld computers are a valuable
tool for physicians by allowing them to have immediate access
to relevant clinical information such as drug interactions,
calculating important parameters, or expanding the
differential diagnosis, providing a readily accessible and
permanent means of recording and tracking patient procedures,
enabling fluid transfer of vital patient information to other
health care providers, and managing and accessing patient
data.
Objectives:
– Familiarity with common
medical applications using Pocket PCs
– Ability to integrate effective usage of PDAs in clinical
decision-making
– Understand the importance of creating and/or sustaining a
robust wireless network in a patient care facility
– Keep abreast of the technological advances in medical
education and patient care in the 21st century
Format: (1) Hands-on, real-time
demonstration of applications using Pocket PCs, (2)
interactive discussion and (3) problem solving with examples.
3:15pm–5:15pm
2760—Designing a Longitudinal Curriculum in
Evidence-Based Medicine for Large Residency Programs
PAS Educational Workshop
Golden Gate Hall C3, SF Marriott
Leader: Srinivasan Suresh, Detroit, MI; Co-leaders: Anne
Mortensen, Misa Mi, Munirah Curtis, Renato Roxas, Joshua
Evans, Kate Sheppard, Lakshmi Srinivasan, Deepak Kamat
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty, senior faculty,
and community practitioners.
Evidence-based medicine (EBM) is
a complementary approach to clinical practice that applies the
principles of clinical epidemiology to the traditional skills
of patient care. A longitudinal curriculum is vital in
inculcating this concept in medical students, residents and
fellows.
This workshop will enable
participants to effectively design an EBM curriculum to
trainees. The workshop leaders currently perform this activity
in a large residency program of about 100 residents. The
logistics of ensuring that all residents are exposed to the
spectrum of EBM, given their other responsibilities, will be
explained. Means of incorporating continual feedback in the
curriculum to achieve best clinical practices will also be
demonstrated.
Objectives:
– Ability to develop formal
clinical questions based on patient encounters
– Ability to develop skills in finding evidence based
medical literature
– Ability to explain the EBM process to peers and trainees
– Acquire the operational skills necessary to
institute/improve an EBM curriculum
Format: (1) Interactive
Discussion, (2) hands-on, real-time demonstration of
literature search strategies using Personal Digital Assistants
(PDA), and (3) problem solving, applying common clinical
vignettes.
3:15pm–5:15pm
2766—Personal Health Records (PHRs) and
Personal Digital Assistants (PDAs): A Hands-on Demonstration
To Promote Family-Centered Care
PAS Educational Workshop
Pacific Suite J, SF Marriott
Leader: Donna Ettel, Saint Petersburg, FL; Co-leader: Lisa
Simpson
Target Audience: Junior faculty,
mid-level faculty, and community practitioners.
There is a great deal of interest
within both the public and private sectors in encouraging all
health care providers to migrate from paper-based health
records to a system that stores health information
electronically and employs computer-aided decision support
systems.
This workshop provides an
opportunity for participants to: (1) increase their
understanding of the clinical benefits of the application of
HIT platforms into the provider settings with an emphasis on
the role of family controlled PHRs and (2) navigate examples
of PHR's and e-prescribing models with online data sharing and
interoperability models. It will also provide the opportunity
for a discussion on lessons learned.
Objectives:
– Provide an overview of
information technology diffusion into health provider settings
in general, with emphasis on personal digital assistants and
personal health records including provider names, medications,
treatments and immunization records.
– Provide participants an opportunity to access an example
of an electronic personal health record from the patient and
physician portals.
– Provide participants an opportunity to navigate through an
online survey of the identified data that will assess the home
environment, family health history and insurance coverage.
– Providing participants an opportunity to navigate through
a wireless system (PDA) to fully access instant, current and
accurate prescription histories and decision support including
vital patient specific pharmacological information.
Format: (1) Power point
presentation (overview); (2) hands on workshop with hands on
computer navigation, (3) round table discussion, and (4)
question and answer.
3:15pm–5:15pm
2774—Telemedicine and Its Applications in
Pediatrics: Improving Quality and Addressing Access Barriers
PAS Educational Workshop
Room Golden Gate Hall C2, SF Marriott
Leader: James Marcin, Sacramento, CA; Co-leader: Stacey Cole
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty, senior faculty,
and community practitioners.
This workshop will provide an
overview of telemedicine, and demonstrate how telemedicine
assists in the care of pediatric patients in various settings.
Interactive lectures will be given on the critical components
of a successful telemedicine program. Video clips of
consultations and interviews will be shown to provide an
understanding of telemedicine from various perspectives. A
step-by-step process will be laid out to help evaluate the
possibility of using telemedicine for their services.
Panelists: Juan Trujano, Anita
Grady and Kristi MacLeod
Objectives:
– To understand the technology
of telemedicine, including telecommunications.
– To become familiar with the important structural,
managerial and financial considerations of telemedicine.
– To understand the impact of telemedicine on measures of
quality of care and satisfaction.
Format: This workshop will
primarily be conducted in a lecture/panel format. Sessions
will be interactive and include discussion, sample video
clips, and a live demonstration of equipment and telemedicine
consultations.
Sunday, April 30
8:00am–11:00am
3240—Manuscript Preparation and the Process
of Peer-Reviewed Publication
PAS Educational Workshop
Willow, SF Marriott
Leader: Stephen Daniels, Denver, CO; Co-leaders: Thomas Welch,
Robert Wilmott, Sarah Long
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty, senior faculty,
community practitioners.
This interactive workshop will
address multiple aspects of publication in scientific journals
and provides insights from editors of The Journal of
Pediatrics on the publication process. Presenters will discuss
preparation of materials, including the initial decision that
the data are sufficient to justify publication. Issues related
to manuscript writing will include length, focus, adherence to
journal formats, and referencing. The editorial process, from
submission to publication, will be described in depth, with
particular attention to ways in which authors can interact
with journal editors. Another section of the workshop will
cover ethical issues in publication including review boards,
authorship, duplicate publication, intellectual property
rights, and conflict of interest. There will be open
discussion of sample cases and questions derived from the
experiences of the participants.
Objectives:
– To learn about preparing and
submitting work for publication in peer-reviewed journals.
– To discuss ethical issues related to publication of
research and clinical work.
– To have the opportunity to ask and have answered questions
about publication and to offer insights.
Format: Open discussion,
question-and-answer.
Designed to meet elements of the
core curriculum for pediatric fellowship subspecialty
training.
2:00pm–5:00pm
3740—AAP Presidential Plenary and First
Annual Silverman Lecture
AAP Presidential Plenary
Room 3007-3011, Moscone West
Chair: Errol R. Alden, American Academy of Pediatrics, Elk
Grove Village, IL
Target Audience: Scientists and
clinicians interested in the translation of research and
evidence-based principles into health policy and practice.
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AAP Presidential Address
Eileen M. Ouellette, President, American Academy of Pediatrics, Elk
Grove Village, IL
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The Community Pediatrics Training
Initiative: Quality Resident Education in Community
Pediatrics
Jeffrey M. Kaczorowski, University of Rochester, Strong Memorial
Hospital, Rochester, NY
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The Scientific Underpinnings of
Preventive Services for Children: The Bright Futures
Project
Paula M. Duncan, University of Vermont, Burlington, VT
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The Evidence Base Underlying
Pay-for-Performance Initiatives
Paul V. Miles, The American Board of Pediatrics, Chapel Hill, NC
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Introduction
Gerald B. Merenstein, University of Colorado School of Medicine,
Aurora, CO
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First Annual William A. Silverman
MD Lecture:
From Disasters to Triumphs—Lessons Learned in the
Evolution of Neonatology as a Subspecialty
Avroy A. Fanaroff, Case Western Reserve University School of Medicine,
Cleveland, OH
The Silverman Lecture
is sponsored by the AAP Section on Perinatal Pediatrics
2:00pm–5:00pm
3769—See One, Do One, Teach
One...Documenting Lifelong Learning
PAS Educational Workshop
Room Yerba Buena Gardens Salon 12, SF Marriott
Leader: Lisa Leggio, Augusta, GA; Co-leaders: Carol Carraccio,
Henry Bernstein, Theodore Sectish, Susan Guralnick
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty, senior faculty,
and community practitioners.
The ABP and the ACGME require
evidence of lifelong learning for maintenance of certification
and training accreditation, respectively. The AAP has updated
PediaLink®, a web-based resource for continuous professional
development, to document practice-based learning and
improvement. The Learning Center, Resident Center and Program
Director Center components of PediaLink® will be presented as
tools for documenting PBLI and learning plans throughout a
pediatric career. Groups will participate in exercises
documenting learning plans and mentoring others through the
process.
Objectives:
– Know how to use PediaLink®
as a resource to document lifelong learning along a continuum
in medical education.
– Create an individual focused and efficiently managed
practice-based, learning plan.
– Teach colleagues and trainees alike to do the same
exercise with their own personal learning plans.
Format: Mini-presentation,
buzzgroup/brainstorming, and small group discussions.
Designed to meet elements of the
core curriculum for pediatric fellowship subspecialty
training.
2:00pm–5:00pm
3788—Medical Informatics
APA Special Interest Group
Sierra Suite F, SF Marriott
Chair: Donna D'Alessandro, donna-dalessandro@uiowa.edu.
4:15pm–5:45pm
3810—RNA Interference, Technological
Development of siRNAs and Potential Treatments for Childhood
Diseases
PAS State of the Art Plenary
Room 3016-3018, Moscone West
Chair: R. Alan B. Ezekowitz, Harvard Medical School,
Massachusetts General Hospital, Boston, MA
Target Audience: Basic scientists
studying a broad range of childhood diseases, translational
scientists of all disciplines studying clinical implications
of basic science research, clinical scientists studying
childhood and other diseases in need of improved therapies and
clinicians interested in cutting-edge science and its medical
implications.
RNA interference is a recently
discovered, naturally occurring intracellular process that
regulates gene expression through the silencing of specific
mRNAs. Methods of harnessing this natural pathway are being
developed that allow the catalytic degradation of targeted
mRNAs using specifically designed complementary small
inhibitory RNAs (siRNA). siRNAs are being chemically modified
to acquire drug-like properties. Numerous recent high-profile
publications have provided proofs of concept that RNA
interference may be useful therapeutically. Much of the design
of these siRNAs can be accomplished bioinformatically, thus
potentially expediting drug discovery and opening new avenues
of therapy for many childhood diseases including uncommon
pediatric and orphan diseases. A discussion of the science
behind RNA interference will be followed by a presentation of
the potential practical issues in applying this technology to
disease. The program then describes two therapeutic programs
currently under way with applications to pediatric diseases. A
question-and-answer time will follow each discussion.
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The Science of RNA Interference
John J. Rossi, Beckman Research Institute of City of Hope, Duarte, CA
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RNA Interference and Its
Potential Applications for Controlling Disease
Judy Lieberman, CBR Institute for Biomedical Research and Harvard
Medical School, Boston, MA
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Silencing the VEGF Pathway with
siRNAs and the Potential Application to Retinopathy of
Prematurity
Pamela Pavco, Sirna Therapeutics, Boulder, CO
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siRNA as Therapy for Respiratory
Syncytial Virus
John P. DeVincenzo, University of Tennessee School of Medicine,
Memphis, TN
Monday, May 1
3:00pm–5:00pm
4650—CPCCRN: The NICHD Collaborative
Pediatric Critical Care Research Network
PAS Educational Workshop
Room 2004, Moscone West
Leader: Carol Nicholson, Bethesda, MD; Co-leader: Douglas
Willson
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty, and community
practitioners.
There are 10,500 critically ill
and injured children admitted each year to the PICUs covered
in the Network. We would welcome the opportunity to interact
with all of the pediatric subspecialties in the context of
PAS. Our work and our research are interwoven with each
pediatric subspecialty as well as with pediatric surgery and
surgical subspecialties.
Objectives:
– How cutting edge informatics
can be used for collaborative pediatric research.
– Understand the Network structure, vision and function, in
a multidisciplinary field.
– Learn about new approaches to nosocomial infection during
critical illness.
Format: An introductory
presentation of Network structure and function, with emphasis
on innovation in collaborative research will begin the
workshop. A series of pediatric critical care scientists will
present some of the newer work being undertaken in the Network
in informatics, sedation, immunology, infectious disease, and
outcomes after pediatric critical illness and injury.
Here is a specific overview, with
each speaker being available for questions, and audience
interaction.
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The CPCCRN: Overview
Douglas Willson, MD
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Functional Disability Outcomes
in Pediatric Critical Care
Murray Pollack, MD
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Toward Science-Based
Guidelines for Sedation and Mechanical Ventilation in
Pediatric Critical Care
Christopher Newth and/or Sunny Anand
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Nosocomial Sepsis and
Lymphocytic Apoptosis: GI Prophylaxis, Glutamine and Zinc
in Pediatric Critical Illness
Joseph Carcillo, MD
3:00pm–5:00pm
4662—Standardizing Prescription of Fluids
and Medications in the NICU: Principles, Practical Tools and
Applications
PAS Educational Workshop
Yerba Buena Gardens Salon 3, SF Marriott
Leader: Joaquim Pinheiro, Albany, NY; Co-leaders: Amy
Mitchell, Vinay Vaidya
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty, senior faculty,
community practitioners, pharmacists, and nurses.
Emphasis on patient safety has
led some NICUs to implement standardized dosing methods,
replacing customized fluid and medication dosing in neonates.
JCAHO has mandated a transition from
"rule-of-6"-based prescription to standardized
concentrations. Without national standards, NICU practitioners
are struggling to comply with the mandate.
Workshop goals are to review
principles of error prevention in NICU, focusing on
standardized methods of prescription and administration. The
leaders will share their experience with paper, electronic and
logistic systems for standardizing fluid, medication and TPN
prescription.
Objectives:
– Participants will learn a
variety of practices and tools used to implement standardized
prescription in NICUs.
– Participants will have practiced multidisciplinary
development of solutions to standardized prescription relevant
to their institutions.
– Participants will learn about computerized methods for
rapid implementation of standardized infusions.
Format: Short presentations,
question-and-answer periods, and problem solving in groups.
Tuesday, May 2
8:45am–11:45am
5224—Using Electronic Health Records for
Pediatric Research and Quality Improvement
PAS Educational Workshop
Yerba Buena Gardens Salon 13, SF Marriott
Leader: Robert Grundmeier, Philadelphia, PA; Co-leaders:
Christoph Lehmann, Su-Ting Li, Stuart Weinberg, William Adams,
Richard Shiffman, Aaron Carroll
Target Audience: Trainees,
fellows, and junior faculty.
While the potential of the
electronic health record (EHR) as a permanent data repository
has gained widespread acceptance, this workshop will introduce
the implications for research and quality improvement (QI)
efforts. Participants will work together in small groups to
design a research question that may be answerable with EHR
data. Using sample data, each group will extract and
manipulate data from the EHR in order to address their
question. Participants are expected to raise methodological
questions based on the exercises and their previous
experiences. An expert panel will respond to these questions
and provide solutions.
Objectives:
– Participants will better
understand electronic health record (EHR) technologies and the
strengths and weakness of EHR data.
– Participants will learn to extract and process aggregate
EHR.
– Participants will better understand regulatory issues
related to IRB guidelines, HIPAA, and data use agreements.
Format: A brief dadaistic lecture
will introduce key aspects of working with EHR data. Hands-on
exercises mentored by medical informaticians will be completed
in small groups with a demonstration dataset. An expert panel
will respond to the participant's questions.
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