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Saturday, April 29
8:00am–11:00am
2130—Newborn Hearing Screening: From the
Bedside to Beyond
PAS/PIDS Mini Course
Room 3010, Moscone West
Chairs: Mark R. Schleiss and Lisa Ann Schimmenti, University of
Minnesota Medical School, Minneapolis, MN
Target Audience: General
pediatricians, geneticists and infectious disease specialists.
Sensorineural hearing loss (SNHL)
in infants is the most common birth defect, and early
detection improves outcome. Evidence from the CDC reveals that
less than one half of screened babies are followed up. One
possible reason is the low positive predictive value of
bedside screening. There is a critical need to augment current
strategies to prevent late diagnosis of SNHL. One solution is
to propose second-tier testing for the most common causes of
SNHL, as the most common causes of newborn hearing loss are
infectious and genetic. Of infectious causes, cytomegalovirus
(CMV) is the most common. Evidence of CMV infection can be
found in 1% of newborns, with 10–15% developing hearing loss
or other CNS abnormalities. Of the genetic causes, mutations
in GJB2/GJB6 are the most common and are identified in up to
one half of individuals with SNHL. The goal of this program
will be to examine evidence for inclusion of infectious and
genetic screening to augment current newborn screening
protocols.
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Diagnostic Evaluation and
Management of Childhood Hearing Loss
Margaret Alene Kenna, Children's Hospital Boston, Boston, MA
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Range of Mutations in
GJB2-Associated Hearing Loss
Lisa Ann Schimmenti, University of Minnesota Medical School,
Minneapolis, MN
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Congenital Cytomegalovirus
Infection and Hearing Loss
Karen B. Fowler, University of Alabama at Birmingham, Birmingham, AL
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Newborn Hearing Screening:
Audiologic Assessment
Yvonne Sininger, University of California Los Angeles, Los Angeles, CA
Sponsored jointly by
the Pediatric Infectious Diseases Society and the Pediatric
Academic Societies
8:00am–11:00am
2158—The National Survey of Children's
Health: Resources and Tips for Using New National and State
Data on Child and Adolescent Health
PAS Educational Workshop
Pacific Suite J, SF Marriott
Leader: Christina Bethell, Portland, OR; Co-leaders: Stephen Blumberg,
Debra Read
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty, senior faculty,
and community practitioners.
The National Survey of Children's
Health (NSCH) is the largest, nationally representative survey
conducted with families to assess the health, well-being and
health care of children and youth (n = 102,000). Publicly
released in 2005, NSCH provides a wide range of national and
state-level data on the health of children, youth and
families. Participants will: 1) identify research topics that
can be addressed using the NSCH; 2) Obtain hands-on experience
using the Data Resource Center—a new resource to easily
obtain and download findings from the NSCH; 3) gt ideas on
using findings to stimulate efforts to improve care for
children, inform research and grant development and advance
evidence-based policy, program development, and advocacy.
Objectives:
– Identify the range of
research topics that can be addressed using these data.
– Obtain hands-on experience using the Data Resource Center
on Child and Adolescent Health (DRC)—a new resource for
pediatric clinicians, researchers, and families to easily
obtain and download findings from the NSCH (www.childhealthdata.org).
– Get ideas on presenting findings to enhance state and
local efforts to improve the health and health care of
children, youth, and families.
Format: Presentations, question
and answer, hands-on practice using an online data resource
center, case examples, real time technical assistance and
problem solving.
9:45am–11:45am
2200A—Clinical Trials and Observational
Studies
ASPN Workshop
Room 2007, Moscone West
Chairs: Susan L. Furth, Johns Hopkins University, Baltimore, MD; and
Craig Wong, Children's Hospital of New Mexico, Albuquerque, NM
Target Audience: Clinical
investigators and pediatric nephrologists.
This workshop will address
statistical, measurement, ethical and regulatory issues in
clinical research. We will discuss methodological issues in
randomized clinical trials when the sample size is limited, as
often occurs in pediatric studies. We will also address the
measurement of kidney function in large cohort studies.
Finally, we will have an extended discussion on the evolution
of the current regulatory system of clinical research in the
United States. This has evolved from concerns about ethical
issues and protection of subjects to concerns about protection
of the institution through compliance with inflexible
requirements. The session will end with suggestions on what
changes are needed and how to achieve them in the current
regulatory environment.
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Introduction
Catherine Stehman-Breen, Amgen, Thousand Oaks, CA
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Methodologic Issues in Clinical
Trials When Sample Size Is Limited
Tom Greene, The Cleveland Clinic, Cleveland, OH
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Measurement of Glomerular
Filtration Rate in Large Cohort Studies: Design, Conduct
and Analysis
Alvaro Munoz, Bloomberg School of Public Health, Johns Hopkins
University, Baltimore, MD
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The Dysregulation of Research
Norman Fost, University of Wisconsin Medical School, Madison, WI
Supported by an unrestricted educational grant from the
Kidney and Urology Foundation of America, Inc. (KUFA)
11:45am–2:45pm
2412—Mobilizing High-Risk Communities To
Prevent Injuries to Youth
PAS Educational Workshop
Willow, SF Marriott
Leader: Michael Gittelman, Cincinnati, OH; Co-leaders: Wendy Pomerantz,
Andrea Gielen, and Mahseeyahu Selassie
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty and community
practitioners.
The purpose of this workshop is
to expand the participants' skills in advocating for
high-risk, underserved communities through local involvement.
The first portion of this workshop will concentrate on how to
obtain and utilize data to identify high-risk communities and
their needs. How to prevent injuries will be the example
given; yet this model could work for any community
intervention. The second portion of the workshop will be
interactive with breakouts into small groups. Skill building
groups will address: 1) the use of focus groups for strategic
thinking/planning; 2) obtaining community buy-in; 3) and
identifying and enhancing existing resources to approach a
common goal. Areas of success and pitfalls in local efforts
will be shared.
Objectives:
– Assessing a communities needs
– Community mobilization/interaction
– Obtaining funding support for community programs
Format: Roundtable discussion,
question-and-answer session, problem solving skills.
2:15pm–5:15pm
2705—Vitamin D: More Than Just Calcium and
Bone
PAS/LWPES Mini Course
Room 3007-3009, Moscone West
Chairs: Catherine M. Gordon, Children's Hospital of Boston, Boston, MA;
and Linda A. DiMeglio, Indiana University, Indianapolis, IN
Target Audience: General
pediatricians, gastroenterologists, endocrinologists and
hematologists/oncologists.
The understanding of the role of
vitamin D in health and illness is becoming more complex. Both
skeletal and extra-skeletal actions have been described, and
vitamin D analogs are being explored for their anti-proliferative
effects. The attendee will gain both clinically relevant
epidemiological knowledge as well as review the calcemic and
non-calcemic actions of Vitamin D.
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What Is the Evidence for Vitamin
D Deficiency in Children?
Frank R. Greer, University of Wisconsin, Madison, WI
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Vitamin D and Extra-Skeletal
Actions in Health
Michael F. Holick, Boston University School of Medicine, Boston, MA
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Non-calcemic Actions of Vitamin D
Receptor Ligands
Sunil Nagpal, Women's Health & Musculoskeletal Biology,
Collegeville PA
Sponsored jointly by
the Lawson Wilkins Pediatric Endocrine Society and the
Pediatric Academic Societies
3:15pm–5:15pm
2725—Integrating Genetic Susceptibility and
Environmental Influences in Pediatric Research
PAS Topic Symposium
Room 2008, Moscone West
Chair: Bruce P. Lanphear, Cincinnati Children's Environmental Health
Center, Cincinnati Children’s Hospital Medical Center,
Cincinnati, OH
Target Audience: A broad
pediatric audience with the goal of promoting
interdisciplinary understanding and greater integration of
genetic and environmental research.
Asthma, preterm birth, ADHD and
other prevalent pediatric conditions are widely recognized to
result from interactions of environmental influences and
genetic susceptibility. Tremendous progress has been made in
measuring both environmental and genetic risk factors.
Increasingly, researchers are moving beyond ecological methods
(e.g., questionnaires, air monitoring) to directly measure in
humans hundreds of environmental chemicals, from nicotine to
metals to DDT and phthalates. Similarly, unprecedented
innovation has led rapidly to high-throughput methods that
assess DNA variation across large cohorts. New
interdisciplinary collaborations that integrate state of the
art approaches to both environmental and genetic influences
should greatly improve our ability to predict and prevent
disease and disability. Such studies will be critical for
understanding mechanistic pathways, defining susceptible
subpopulations and developing effective interventions. This
session will provide an overview of gene–environment
research, describe recent advances in biomarkers of
environmental exposure and review new methods for measuring
genetic variability.
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Gene–Environment Interaction in
Common Pediatric Conditions: Conceptual Overview and
Recent Evidence
Robert S. Kahn, Cincinnati Children’s Hospital Medical Center,
University of Cincinnati College of Medicine, Cincinnati,
OH
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Advances in Biomarkers of
Environmental Exposure in Pediatric Research
Bruce P. Lanphear, Cincinnati Children's Environmental Health Center,
Cincinnati Children’s Hospital Medical Center,
Cincinnati, OH
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Measuring Genetic Susceptibility
to the Environment: Study Designs and Genotyping Methods
Robert O. Wright, Harvard Children's Environmental Health Center,
Boston Children's Hospital and the Harvard School of
Public Health, Boston, MA
3:15pm–5:15pm
2762—How To Evaluate Medical Literature
PAS Educational Workshop
Golden Gate Hall B3, SF Marriott
Leader: William King, Birmingham, AL
Target Audience: Trainees,
fellows, junior faculty, and other health care professionals.
How to Evaluate the Medical
Literature. All scientific work must be subjected to rigorous
critical appraisal. Although peer review precedes most
published medical reports, significant methodological flaws
survive the peer review process. Thus, the ultimate evaluation
and judgment of the quality of published reports remains with
the reader. This workshop will introduce the importance of
developing critical appraisal skill, discuss important
concepts related to manuscript and journal quality, identify
six potential problem areas in a study's methodology, review
and apply up to four quantifiable evaluation instruments,
assign quality scores to a journal article using one of the
instruments, discuss the elements of a good review and apply a
review quality instrument to rate the participant's review of
a journal article.
Objectives:
– Understand the importance of
developing critical appraisal skills.
– Understand the following concepts: quality filtering, peer
review, publication bias, journal quality indicators, CONSORT,
RQI.
– Identify and apply up to 4 evaluation instruments for
evaluating journal articles.
– Identify and apply a review quality instrument.
Format: Introductory lecture and
discussion, followed by the participant's application of an
evaluation instrument, participant quality scoring of a
published article and scoring of the critical review provided
by the participant (using a review quality instrument).
Designed to meet elements of the
core curriculum for pediatric fellowship subspecialty
training.
5:15pm–6:00pm
2800—Clinical Pediatric Hypertension
PAS/ASPN/IPHA Poster Symposium
Room 2004, Moscone West
Chairs: Stephen R. Daniels and Deborah P. Jones
Sponsored jointly by
the International Pediatric Hypertension Association and the
American Society of Pediatric Nephrology
Sunday, April 30
8:00am–10:00am
3135—Environmental Health: Exposures and
Outcomes
PAS Platform Session
Room 2002, Moscone West
Chairs: Ellen F. Crain and Bruce P. Lanphear
8:00am–11:00am
3236—Evidence-Based Advocacy: Turning
Research into Action
PAS Educational Workshop
Golden Gate Hall C3, SF Marriott
Leader: Dennis Durbin, Philadelphia, PA; Co-leaders: Flaura Winston,
Suzanne Hill
Target Audience: junior faculty,
mid-level faculty, senior faculty, and community
practitioners.
Evidence-based advocacy
integrates the often independent, yet complementary, efforts
of clinicians, researchers, public health officials,
policymakers and the media to apply scientific principals to
widespread health promotion and prevention initiatives.
Through case-based illustrations, small-group skill building
and brainstorming exercises, workshop participants will learn
the critical steps involved in translating research results
into a variety of complementary advocacy activities to advance
children's health and safety. Strategies including public
education through the media, social marketing techniques,
legislative advocacy and working collaboratively with industry
will be reviewed and discussed. At the completion of the
workshop, participants will better understand how to plan and
conduct successful advocacy activities for the children in
their communities and will know how to access relevant
resources in support of their work.
Objectives:
– Learn the steps involved in
translating research into a variety of advocacy activities.
– Understand the complementary nature of distinct advocacy
activities.
– Practice translating research results into messaging.
– Develop a strategic plan for advocacy.
Format: Case-based
demonstrations, group discussion, and small break-out group
skill-building.
2:00pm–4:00pm
3700—Developing Valid and Relevant Outcome
Measures for Pediatric Emergency Medicine
PAS Topic Symposium
Room 2008, Moscone West
Chairs: Evaline A. Alessandrini, The Children's Hospital of
Philadelphia, Philadelphia, PA; and Marc H. Gorelick,
Children's Hospital of Wisconsin, Milwaukee, WI
Target Audience: Pediatric and
general emergency medicine physicians and/or any health care
professional or researcher interested in outcomes and quality
improvement.
To improve quality, the Institute
of Medicine (IOM) proposes that health care be safe,
effective, patient-centered, timely, efficient and equitable.
Research using important and relevant outcome measures can
distinguish differences in quality of care between health
practitioners, settings and patient populations, including
factors such as race/ethnicity or socioeconomic status.
Defining and accurately measuring outcomes are vital to both
clinical research and practice. Yet valid and relevant outcome
measures that are applicable to all children receiving
emergency care have not been developed or agreed upon.
Features of important clinical outcomes include credibility,
comprehensiveness, sensitivity, accuracy, biologic sensibility
and feasibility. This session will review general (as opposed
to condition-specific) outcome measures for use in pediatric
emergency medicine, focusing on strengths and weaknesses as
well as their relationship to the IOM quality domains.
Speakers will discuss outcome and process measures such as
health-related quality of life; satisfaction, confidence and
trust in health care; mortality; admission rates; emergency
department recidivism; length of stay; and costs. A discussion
and question-and-answer period will end the session.
-
Introduction
Evaline A. Alessandrini, The Children's Hospital of Philadelphia,
Philadelphia, PA
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Mortality and Admission Rates
James M. Chamberlain, Children's National Medical Center, Washington,
DC
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Emergency Department Length of
Stay, Costs and Satisfaction
Marc H. Gorelick, Children's Hospital of Wisconsin, Milwaukee, WI
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Emergency Department Recidivism,
Confidence and Trust in Health Care Practitioners
Evaline A. Alessandrini, The Children's Hospital of Philadelphia,
Philadelphia, PA
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Health-Related Quality of Life
Martha (Molly) W. Stevens, Children's Hospital of Wisconsin, Milwaukee,
WI
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Discussion
2:00pm–4:00pm
3705—Infections at the
Maternal–Placental–Fetal Interface: Immunopathogenesis of
Group B Streptococcus, Listeria monocytogenes and
Cytomegalovirus
PAS/PIDS Topic Symposium
Room 3022-3024, Moscone West
Chairs: John R. Schreiber, University of Minnesota Medical School and
University of Minnesota Children's Hospital/Fairview,
Minneapolis, MN; and Robert F. Pass, University of Alabama at
Birmingham, Birmingham, AL
Target Audience: Neonatologists,
infectious disease specialists, immunologists, developmental
biologists and general pediatricians.
Infections in newborns commonly
result from acquisition either during the delivery process or
transplacentally. The host and pathogen factors that
contribute to acquisition of infections at the
maternal–placental–fetal interface are poorly understood.
This symposium will review the basic science and
immunopathogenesis of three diverse pathogens that all share
the ability to cause infections at the placental level:
cytomegalovirus, group B streptococcus, and Listeria
monocytogenes.
-
Intrauterine Cytomegalovirus
Infection, Transplacental Spread of Virus and Control by
Maternal Immunity
Lenore Pereira, University of California San Francisco, San Francisco,
CA
-
Host and Bacterial Factors in
Invasive Group B Streptococcal Infection
Craig E. Rubens, University of Washington, Seattle, WA
-
Listeriosis in the Pregnant
Guinea Pig: A Model of Vertical Transmission
Daniel A. Portnoy, University of California Berkeley, Berkeley, CA
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Discussion
Sponsored jointly by
the Pediatric Infectious Diseases Society and the Pediatric
Academic Societies
2:00pm–4:00pm
3716—Epidemiology I
PAS Platform Session
Room 2011, Moscone West
Chairs: Diane L. Langkamp and Marshalyn Yeargin-Allsopp
2:00pm–5:00pm
3740—AAP Presidential Plenary and First
Annual Silverman Lecture
AAP Presidential Plenary
Room 3007-3011, Moscone West
Chair: Errol R. Alden, American Academy of Pediatrics, Elk Grove
Village, IL
Target Audience: Scientists and
clinicians interested in the translation of research and
evidence-based principles into health policy and practice.
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AAP Presidential Address
Eileen M. Ouellette, President, American Academy of Pediatrics, Elk
Grove Village, IL
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The Community Pediatrics Training
Initiative: Quality Resident Education in Community
Pediatrics
Jeffrey M. Kaczorowski, University of Rochester, Strong Memorial
Hospital, Rochester, NY
-
The Scientific Underpinnings of
Preventive Services for Children: The Bright Futures
Project
Paula M. Duncan, University of Vermont, Burlington, VT
-
The Evidence Base Underlying
Pay-for-Performance Initiatives
Paul V. Miles, The American Board of Pediatrics, Chapel Hill, NC
-
Introduction
Gerald B. Merenstein, University of Colorado School of Medicine,
Aurora, CO
-
First Annual William A. Silverman
MD Lecture:
From Disasters to Triumphs—Lessons Learned in the
Evolution of Neonatology as a Subspecialty
Avroy A. Fanaroff, Case Western Reserve University School of Medicine,
Cleveland, OH
The Silverman Lecture
is sponsored by the AAP Section on Perinatal Pediatrics
2:00pm–5:00pm
3750—Endocrine Disrupters
PAS/LWPES Mini Course
Room 3010-3012, Moscone West
Chairs: Mary M. Lee, University of Massachusetts Medical School,
Worcester, MA; and Henry Anhalt, Saint Barnabas Medical
Center, Livingston, NJ
Target Audience:
Endocrinologists, generalists, neonatologists and basic
scientists.
Concerns regarding clinical
consequences of endocrine disrupting chemicals have increased
over the past decade as researchers have documented
detrimental effects in wildlife. Federal attention to
endocrine disrupters began in earnest in 1996 when the U.S.
Congress passed the Food Quality Protection Act and amended
the Safe Drinking Water Act. These laws mandated testing to
determine if pesticides and industrial chemicals might behave
like hormones; therefore, the U.S. EPA formed the Endocrine
Disrupters Screening and Advisory Committee. In addition to
direct effects, some environmental disrupters act through
non-genomic actions, some of which persist for several
generations. This program presenting innovative studies on
mechanisms of action of endocrine disruptors will be of
critical interest to endocrinologists, both clinical and basic
scientists, as well as public health experts.
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Prenatal Programming with
Estrogen/Estrogen Mimetics
Kenneth S. Korach, National Institute of Environmental Health Sciences,
Research Triangle Park, NC
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Epigenetic Transgenerational
Actions of Endocrine Disruptors on Male Fertility and
Other Diseases
Michael K. Skinner, Washington State University, Pullman, WA
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Prenatal Programming with Native
and Environmental Steroids
Vasantha Padmanabhan, University of Michigan, Ann Arbor, MI
Sponsored jointly by
the Lawson Wilkins Pediatric Endocrine Society and the
Pediatric Academic Societies
4:15pm–5:45pm
3805—Fetal Homeland Security: New Insights
into Old Threats
PAS State of the Art Plenary
Room 3002-3008, Moscone West
Chairs: Phil W. Shaul, University of Texas Southwestern Medical Center,
Dallas, TX; and Rashmin C. Savani, University of Texas
Southwestern Medical Center, Dallas, TX
Target Audience: Neonatologists,
pediatricians and researchers interested in perinatal biology.
In addition to premature birth,
there are a select number of maternal conditions that have
marked negative impact on the well being of the fetus and
newborn. This symposium will highlight recent advances in our
understanding of these classical threats to our most
vulnerable pediatric patient population.
First, new knowledge of the
mechanisms by which maternal diabetes alters embryonic and
fetal development will be discussed. Second, the newly
discovered role of circulating anti-angiogenic proteins of
placental origin in the pathogenesis of preeclampsia will be
presented. Finally, novel mechanisms by which biochemical
events in the fetal lung trigger the initiation of labor will
be discussed. Further advances in each of these realms will
ultimately lead to new therapies to protect the fetus and
yield healthy outcomes at term.
-
Mechanisms by Which Maternal
Diabetes Modifies Embryonic and Fetal Development
Kelle H. Moley, Washington University School of Medicine, St. Louis, MO
-
Role of Circulating Anti-angiogenic
Proteins of Placental Origin in the Pathogenesis of
Preeclampsia
S. Ananth Karumanchi, Harvard Medical School, Beth Isreal Deaconess
Medical Center, Boston, MA
-
Fetal–Maternal Signaling in the
Initiation of Labor
Carole R. Mendelson, University of Texas Southwestern Medical Center,
Dallas, TX
4:15pm–6:15pm
3850—Human Milk and Breastfeeding
PAS Poster Symposium
Room 3001, Moscone West
Chairs: Sheela R. Geraghty and Ardythe L. Morrow
4:15pm–6:15pm
3870—Neonatal Public Health
PAS Poster Symposium
Room 3014, Moscone West
Chairs: Henrietta S. Bada and Robert A. Sinkin
Includes:
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Douglas K. Richardson Award for
Perinatal and Pediatric Healthcare Research
Marie C. McCormick, Harvard School of Public Health and Harvard Medical
School, Boston, MA
Monday, May 1
9:00am–12:00pm
4223—Design and Conduct of Randomized
Clinical Trials
PAS Educational Workshop
Room Pacific Suite B, SF Marriott
Leader: Mark Klebanoff, Bethesda, MD
Target Audience: Fellows, junior
faculty, mid-level faculty, and senior faculty.
It is now almost universally
required that randomized trials show new treatments to be
superior to current therapy (or no therapy) before the new
treatments are adopted. In this workshop we will go through
the design and conduct of several clinical trials, from
defining the question to conducting the final analysis. The
format is didactic with extensive discussion, and we will base
as much of the workshop as possible on real-world trials
provided by the participants themselves.
Objectives:
– To understand the principles
of trial design, conduct and analysis.
– To improve skills in reading publications of clinical
trial results.
Format: Didactic sessions with
discussion. Real-world examples will be provided by the
participants themselves.
Designed to meet elements of the
core curriculum for pediatric fellowship subspecialty
training.
10:15am–12:15pm
4360—New Perspectives on ADHD
PAS Poster Symposium
Room 2002, Moscone West
Chairs: Marc A. Lerner and Mark L. Wolraich
12:00pm–6:45pm
Commercial Exhibits Open and Posters
Available for Viewing
PAS Exhibits
Levels 1 and 2, Moscone West
Posters Available for Viewing:
12:00pm–6:45pm
Author Attendance: 5:15pm–6:45pm
Level 1:
– Critical Care
– Gastroenterology
– Genetics
– Neonatal Epidemiology and Follow Up
– Neonatal Pulmonology
– Neonatology
– Nephrology
– Pulmonology
Level 2:
– Developmental–Behavioral Pediatrics
– Emergency Medicine
– General Pediatrics
– Medical Education
12:15pm–1:15pm
4470—The National Children's Study: Status
and Future Plans
PAS/PPC Special Symposium
Room 3010-3012, Moscone West
Chair: Elena Fuentes-Afflick, University of California, San Francisco,
CA
Target Audience: Practicing
pediatricians, academic child health professionals,
researchers, administrators and policymakers who are
interested in child health across the lifespan. Professionals
interested in the impact of environmental factors on health
outcomes will also be interested.
This special symposium will
present an update on the National Children's Study, which
recently selected 7 vanguard centers and is prepared to begin
recruitment of subjects. However, the President's budget
proposal allocated no further funding and stated that the
study would be terminated at the end of the current fiscal
year. The panel presenters will discuss the current budgetary
outlook, status of the study, options to implement the study
and respond to questions from the audience.
Panelists:
-
Elena Fuentes-Afflick, University of California, San Francisco, CA
-
Duane Alexander, Director,
National Institute of Child Health and Human Development,
National Institutes of Health, Bethesda, MD
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Peter C. Scheidt, Director,
National Children's Study, National Institute of Child
Health and Human Development, National Institutes of
Health, Bethesda, MD
-
Alan R. Fleischman, Chair,
National Children's Study Federal Advisory Committee, New
York Academy of Medicine, New York and National Institutes
of Health, Bethesda, MD
-
David J. Schonfeld, Member,
National Children's Study Federal Advisory Committee and
Chair, AAP Committee on Research, Cincinnati, OH
Sponsored jointly by
the Public Policy Council and the Pediatric Academic Societies
5:15pm–6:45pm
Poster Session III
PAS Poster Session
Levels 1 and 2, Moscone West
Posters Available for Viewing:
12:00pm–6:45pm
Author Attendance: 5:15pm–6:45pm
Level 1:
– Critical Care
– Gastroenterology
– Genetics
– Neonatal Epidemiology and Follow Up
– Neonatal Pulmonology
– Neonatology
– Nephrology
– Pulmonology
Level 2:
– Developmental–Behavioral Pediatrics
– Emergency Medicine
– General Pediatrics
– Medical Education
Tuesday, May 2
8:00am–10:00am
5100—Ethical Issues in Housing Health
Hazard Research Involving Children
PAS Topic Symposium
Room 2003-2005, Moscone West
Chair: Bernard Lo, University of California San Francisco, San
Francisco, CA
Target Audience: A broad
pediatric audience with the goal of promoting understanding of
ethical issues in conducting community-based research,
especially housing hazard research.
Children’s homes may contain
hazards that can cause lead toxicity, trigger asthma or result
in serious injuries or poisoning. A 2001 court decision, in
Grimes versus Kennedy Krieger Institute, highlighted ethical
issues in housing-related research and led to substantial
controversy and confusion. Many ethical dilemmas occur because
research participants are often poor, members of a minority
group and have few affordable housing options. Moreover,
carrying out research in the home raises unique ethical
issues. A forthcoming report from National Academies of
Science (NAS) will offer recommendations for conducting
research on this topic. This panel will present these NAS
recommendations and discuss how they might be applied to
specific projects in housing research involving children.
Specific issues to be discussed include innovations in
research design and informed consent, responding to risks
observed in the home, the role of researchers and IRBs and
community involvement in research. Audience participation will
be encouraged.
-
Recommendations from the National
Academies of Science
Bernard Lo, University of California San Francisco, San Francisco, CA
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Protecting Vulnerable Research
Participants While Allowing Valuable Research To Be
Carried Out
Alan R. Fleischman, Chair, National Children's Study Federal Advisory
Committee, New York Academy of Medicine, New York and
National Institutes of Health, Bethesda,
MD
-
Innovations in Study Design and
Informed Consent in Housing Hazard Research Involving
Children
Bruce P. Lanphear, Cincinnati Children's Environmental Health Center,
Cincinnati Children’s Hospital Medical Center,
Cincinnati, OH
-
Resolving Ethical Dilemmas in
Housing Hazard Research Through Community Participation
Brenda Eskenazi, University of California Berkeley, Berkeley CA
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Discussion
8:00am–10:00am
5105—Not All Near-Term Infants Are Born
Equal
PAS Topic Symposium
Room 3002-3008, Moscone West
Chairs: Lucky Jain, Emory University, Atlanta, GA; and Tonse N.K. Raju,
National Institute of Child Health and Human Development,
Rockville, MD
Target Audience: Neonatologists
and pediatricians.
Infants born at >34 weeks and
<38 weeks are often presumed to be mature and treated at
par with term infants. However, there is considerable
epidemiologic information to show that these infants have
considerably higher rates of NICU admissions and are at risk
for serious morbidity and death. Causes of morbidity include
delayed respiratory transition and surfactant deficiency,
hyperbilirubinemia, hypothermia, hypoglycemia and poor
initiation of feeding, etc. This symposium is designed to
review the physiological events related to neonatal transition
at birth and the pitfalls in the transition of a near-term
infant. The symposium should create awareness among
neonatologists and pediatricians for these morbidities and
suggest ways to overcome them.
-
Overview
Lucky Jain, Emory University, Atlanta, GA
-
Epidemiology and Overview of
Near-Term Births
Tonse N.K. Raju, National Institute of Child Health and Human
Development, Rockville, MD
-
Respiratory Transition and
Morbidity in Near-Term Infants
Lucky Jain, Emory University, Atlanta, GA
-
Brain Maturation and Pathology in
Near-Term Infants
Hannah Kinney, Harvard University, Boston, MA
-
Hyperbilirubinemia and
Kernicterus in Near-Term Infants
Vinod K. Bhutani, Stanford University School of Medicine, Stanford, CA
-
Post-Discharge Morbidity and
Rehospitalization in Near-Term Infants
Gabriel J. Escobar, Kaiser Permanente, Oakland, CA
-
Discussion
Supported by an unrestricted educational grant from INO
Therapeutics
8:00am–10:00am
5160—Epidemiology II
PAS Platform Session
Room 2002, Moscone West
Chairs: José F. Cordero and Jennifer S. Read
8:45am–11:45am
5216—How To Change the World in an Hour a
Month: Skills for Effective and Efficient Leadership in
Community Health and Child Advocacy
PAS Educational Workshop
Yerba Buena Gardens Salon 4, SF Marriott
Leader: Andy Aligne, Rochester, NY; Co-leaders: Laura Jean Shipley,
Jeffrey Kaczorowski, Danielle Thomas-Taylor
Target Audience: Trainees,
fellows, junior faculty, mid-level faculty, senior faculty,
and community practitioners.
This workshop will enable
attendees to leverage their time more effectively when working
outside the clinical setting to improve child health at the
community level. Facilitated group exercises will improve
skills in some or all of the following: time management,
teamwork, coping with change, getting involved with
community-based organizations, cultural observation, speaking
to the media, project planning and evidence-based community
health.
Objectives:
– Time management
– Speaking to the media
– Project planning
– Evidence-based community health
Format: Group exercises and group
problem solving.
10:00am–2:00pm
Commercial Exhibits Open and Posters
Available for Viewing
PAS Exhibits
Levels 1 and 2, Moscone West
Posters Available for Viewing:
10:00am–2:00pm
Author Attendance: 12:00pm–1:30pm
Level 1:
– Adolescent Medicine
– Emergency Medicine
– Epidemiology
– General Pediatrics
– Infectious Diseases
– Neonatal Epidemiology and Follow Up
Level 2:
– Neonatal Pulmonology
– Neonatology
10:15am–11:45am
5405—Newborn Screening: The Coming
Revolution
PAS State of the Art Plenary
Room 3001, Moscone West
Chair: Alex R. Kemper, University of Michigan, Ann Arbor, MI
Target Audience: General
pediatricians, subspecialists involved with newborn screening,
for including neonatologists, endocrinologists, hematologists
and geneticists.
Newborn screening has resulted in
dramatic improvements in the morbidity and mortality of
inherited disorders. Recent laboratory developments have
dramatically increased the number of conditions that can be
detected in early infancy. Expanding the list of conditions
has lead to unique challenges for pediatric practices and
public health systems. This symposium will explore these new
and emerging challenges.
-
Overview
Alex R. Kemper, University of Michigan, Ann Arbor, MI
-
New Technologies for Newborn
Screening
Edward R.B. McCabe, David Geffen School of Medicine at UCLA, Mattel
Children's Hospital, Los Angeles, CA
-
Meeting the Needs for
Confirmation, Counseling and Treatment
R. Rodney Howell, Miller School of Medicine at the University of Miami,
Miami, FL
-
"Treatment" Versus
"Benefit" in Evaluating the Desirability of
Expanded Newborn Screening
Don Bailey, University of North Carolina at Chapel Hill, Chapel Hill,
NC
-
Ethical Issues That Must Be
Addressed in an Expanded Newborn Screening Program
Ellen Wright Clayton, Vanderbilt University, Nashville, TN
-
Summary Comments
Michele Puryear, Maternal and Child Health Bureau, Health Resources
& Services Administration, Rockville, MD
-
Discussion
10:15am–12:15pm
5425—A Spectrum of Neurodevelopmental
Disabilities
PAS Poster Symposium
Room 2006, Moscone West
Chairs: Bruce K. Shapiro and Robert G. Voigt
12:00pm–1:30pm
Poster Session IV
PAS Poster Session
Levels 1 and 2, Moscone West
Posters Available for Viewing:
10:00am–2:00pm
Author Attendance: 12:00pm–1:30pm
Level 1:
– Adolescent Medicine
– Emergency Medicine
– Epidemiology
– General Pediatrics
– Infectious Diseases
– Neonatal Epidemiology and Follow Up
Level 2:
– Neonatal Pulmonology
– Neonatology
Includes:
-
SPR Student Research Award: Metal
Contamination of Blood Bank Blood
Allison Blatz, Case Western Reserve University, Rainbow Babies &
Children's Hospital, Cleveland, OH
-
SPR House Officer Research Award:
Pathogenesis of Measles Virus Infection in Simian
Immunodefiency Virus-Infected, Measles Virus-Vaccinated
Rhesus Monkeys
Sallie R Permar, Children's Hospital and Boston Medical Center, Boston,
MA
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