Pediatric Academic Societies'
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Mail Address:

3400 Research Forest Dr., Ste B-7
The Woodlands, TX  77381 USA

Email:  info@pas-meeting.org

Telephone:  281-419-0052

Facsimile:  281-419-0082

 

2006 PAS Annual Meeting

April 29–May 2 
San Francisco, California

Track/Area of Interest


At A Glance Page 
(PDF format)

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Schedule Home Page

(as of April 20, 2006) 

Neonatology

Friday, April 28

5:00pm–6:00pm
1610A—Thrombosis—Going with the Flow: Anticoagulation Issues in Children with Congenital Heart Disease
ASPHO Workshop
Golden Gate Hall B2-3, SF Marriott
Chairs: Patricia Massicotte, University of Alberta Hospital, Edmonton, AB, Canada; and Lori Luchtman-Jones, Washington University, St. Louis, MO

Warfarin is commonly used in children with congenital heart disease (CHD). There are many challenges with the use of this anticoagulant in children. Ultimate dosing depends on the individuals genetic composition. Child-focused education on warfarin will improve compliance, efficacy and safety. The hematologist with expertise in anticoagulation can provide child-focused education on anticoagulation and offer the cardiovascular team management solutions for managing the complex issues associated with anticoagulation in children with CHD.

  • Case Study and Discussion
    Therese Giglia, Schneider Children's Hospital, New Hyde Park, NY

  • Child-Focused Education Package: Warfarin
    Mary Bauman, Stollery Children's Hospital, Edmonton, AB, Canada

  • Pharmacogenomics of Warfarin
    Lori Luchtman-Jones, Washington University, St. Louis, MO

  • Keep the Flow: Hematologists as Part of the Cardiovascular Team in Children with Congenital Heart Disease
    Therese Giglia, Schneider Children's Hospital, New Hyde Park, NY

  • Panel Discussion


Saturday, April 29

8:00am–11:00am
2100—Adult Stem Cells—A Primer for the Clinician
PAS/ASPHO Mini Course
Room 3014, Moscone West
Chairs: Jakub Tolar, University of Minnesota, Minneapolis, MN; and Mervin C. Yoder, Jr., Indiana University School of Medicine, Indianapolis, IN

Target Audience: Hematologists/oncologists, endocrinologists, basic scientists and neurologists.

Adult stem cells represent a technology that is being intensively investigated currently, and this research may have wide implications for human health. This mini course will focus on recent research and potential applications in human health.

  • Introduction
    Jakub Tolar, University of Minnesota, Minneapolis, MN
    Mervin C. Yoder, Indiana University School of Medicine, Indianapolis, IN

  • Multipotent Adult Progenitor Cell: Hype or Reality?
    Catherine M. Verfaillie, University of Minnesota, Minneapolis, MN

  • Mesenchymal Stem Cell: Harnessing the Power of Adult Stem Cells To Repair Tissues
    Darwin Prockop, Tulane University Health Science Center, New Orleans, LA

  • Hierarchy of Endothelial Progenitors in Human Blood and Blood Vessels
    David A. Ingram, Indiana University School of Medicine, Indianapolis, IN

  • Cancer Stem Cell: Concept of Human Leukemic Development
    Craig T. Jordan, James P. Wilmot Cancer Center, University of Rochester School of Medicine, Rochester, NY

Sponsored jointly by the American Society of Pediatric Hematology/Oncology and the Pediatric Academic Societies

8:00am–11:00am
2125—New Considerations for the Growth Rate of the Preterm Infant: Too Fast or Not Fast Enough?—A Review of the Evidence
PAS Mini Course
Room 3002-3008, Moscone West
Chairs: Frank R. Greer, University of Wisconsin, Madison, WI; and William W. Hay, Jr., University of Colorado, Aurora, CO

Target Audience: Neonatologists, hospitalists who take care of preterm infants, nutritionists and general pediatricians.

Recent nutritional emphasis in the NICU has been to achieve the normal intrauterine growth rate with more aggressive nutritional support for the low birth weight infant. In general, this has been difficult to achieve, and new evidence from long-term follow up studies shows that preterm infants are at an increased risk of developing the metabolic syndrome including obesity, type 2 diabetes and cardiovascular disease. This implies that the organs in the early life of the preterm infant may be programmed adversely by nutritional therapy. This raises the questions of how fast these infants should grow (including catch up growth), the importance of the composition of this growth and the urgency for defining the necessary balance between growth of the brain and the rest of the body. Ultimately, providers may want to revise the long-term and short-term goals for feeding very low birth weight or extremely low birth weight infants. This mini course will present evidence to help answer these questions and provide discussion about related practice recommendations.

  • Overview
    Frank R. Greer, University of Wisconsin, Madison, WI
    William W. Hay, University of Colorado Health Sciences Center, Aurora, CO

  • Macronutrient Requirements for Growth of Preterm Infants—Upper and Lower Limits (Energy, Fat, CHO, Protein)
    Scott C. Denne, Indiana University School of Medicine, James Whitcomb Riley Hospital, Indianapolis, IN

  • Aggressive Nutritional Support of the Preterm Infant Revisited—Evidence for Efficacy and Safety
    Patti J. Thureen, University of Colorado Health Sciences Center, Denver, CO

  • Adverse Outcomes of Rapid Somatic Growth and Alterations of Body Composition in the Low Birth Weight Infant
    Frank R. Greer, University of Wisconsin, Madison, WI

  • Fatty Acids and Neuronal Development
    Susan E. Carlson, University of Kansas Medical Center, Kansas City, KS

  • Iron and Development of the Brain
    Michael K. Georgieff, University of Minnesota School of Medicine, Minneapolis, MN

  • Nutritional Influences on Structural and Functional Maturation of the Developing Brain During Extended Postnatal Period
    Steve H. Zeisel, The University of North Carolina, Chapel Hill, NC

8:00am–11:00am
2130—Newborn Hearing Screening: From the Bedside to Beyond
PAS/PIDS Mini Course
Room 3010, Moscone West
Chairs: Mark R. Schleiss and Lisa Ann Schimmenti, University of Minnesota Medical School, Minneapolis, MN

Target Audience: General pediatricians, geneticists and infectious disease specialists.

Sensorineural hearing loss (SNHL) in infants is the most common birth defect, and early detection improves outcome. Evidence from the CDC reveals that less than one half of screened babies are followed up. One possible reason is the low positive predictive value of bedside screening. There is a critical need to augment current strategies to prevent late diagnosis of SNHL. One solution is to propose second-tier testing for the most common causes of SNHL, as the most common causes of newborn hearing loss are infectious and genetic. Of infectious causes, cytomegalovirus (CMV) is the most common. Evidence of CMV infection can be found in 1% of newborns, with 10–15% developing hearing loss or other CNS abnormalities. Of the genetic causes, mutations in GJB2/GJB6 are the most common and are identified in up to one half of individuals with SNHL. The goal of this program will be to examine evidence for inclusion of infectious and genetic screening to augment current newborn screening protocols.

  • Diagnostic Evaluation and Management of Childhood Hearing Loss
    Margaret Alene Kenna, Children's Hospital Boston, Boston, MA

  • Range of Mutations in GJB2-Associated Hearing Loss
    Lisa Ann Schimmenti, University of Minnesota Medical School, Minneapolis, MN

  • Congenital Cytomegalovirus Infection and Hearing Loss
    Karen B. Fowler, University of Alabama at Birmingham, Birmingham, AL

  • Newborn Hearing Screening: Audiologic Assessment
    Yvonne Sininger, University of California Los Angeles, Los Angeles, CA

Sponsored jointly by the Pediatric Infectious Diseases Society and the Pediatric Academic Societies

9:00am–11:00am
2196—Modulators of Bronchopulmonary Dysplasia
PAS Platform Session
Room 3003-3005, Moscone West
Chairs: Suhas G. Kallapur and Lawrence M. Nogee

Supported by an unrestricted educational grant from Dey, L.P.

10:30am–12:30pm
2315—Brain Metabolism and Injury: Mechanisms of Neuronal Injury and Neuroprotection
PAS Poster Symposium
Room 3024, Moscone West
Chairs: John D.E. Barks and Jeremy D. Marks

10:30am–12:30pm
2340—Necrotizing Enterocolitis
PAS Platform Session
Room 3022, Moscone West
Chairs: Cheryl E. Gariepy and B U.K. Li

12:00pm–3:00pm
2505—Embryonic Stem Cells: A Primer for Clinicians
PAS Mini Course
Room 3014, Moscone West
Chair: Michael T. Longaker, Stanford University, Stanford, CA

Embryonic stem cells offer incredible promise for treating diseases affecting both children and adults. This mini course will provide an overview of stem cells and a basic understanding of how to derive human embryonic stem cells, recent research and ethical considerations. After attending this session, attendee will have a better understanding of: 1) what are embryonic stem cells; 2) how human embryonic stem cells are derived; 3) recent progress in human embryonic stem cell research; 4) ethical considerations in human embryonic stem cells.

  • Stem Cells: Embryonic, Adult and Cancer
    Michael T. Longaker, Stanford University, Stanford, CA

  • What It Takes Clinically To Get an Embryonic Stem Cell
    Linda C. Giudice, University of California, San Francisco, San Francisco, CA

  • What Can You Do with an Embryonic Stem Cell in Research
    Renee Reijo Pera, University of California, San Francisco, San Francisco, CA

  • Ethical and Oversight Considerations in Human Embryonic Stem Cell Research
    Hank Greely, Stanford University, Stanford, CA

  • Panel Discussion

Supported in part by an unrestricted educational grant from Treuman Katz Center for Pediatric Bioethics - Seattle Children's Hospital

12:30pm–2:30pm
2540—Neonatal Infections
PAS Platform Session
Room 3003-3005, Moscone West
Chairs: Henrietta S. Bada and Jill E. Baley

1:00pm–3:00pm
2610—Genetics and Epigenetics of Neonatal Disease
PAS Platform Session
Room 3022, Moscone West
Chairs: Aaron Hamvas and Jeffrey C. Murray

1:00pm–3:00pm
2630—Neurology
PAS Platform Session
Room 3020, Moscone West
Chairs: Anne M. Comi and Yvonne W. Wu

1:00pm–3:00pm
2635—Respiratory Mechanics at the Bedside—NICU
PAS Platform Session
Room 3002-3008, Moscone West
Chairs: Robert E. Fleming and Howard W. Kilbride

2:15pm–5:15pm
2700—Educating Pediatric Fellows in a Competency-Based World
PAS/APPD Mini Course
Room 2007, Moscone West
Chairs: Susan Guralnick, Stony Brook University Medical Center, Stony Brook, NY; and Joseph Gilhooly, Oregon Health and Science University, Portland, OR

Target Audience: Attendees involved with fellowship programs.

Competency-based education is now the standard for residency education. Residency programs have integrated the ACGME Core Competencies into their curricula and assessment methods. It is now time for fellowships to enter the “competency” arena, and there is much to be accomplished. This program will focus on several areas of fellowship education including: the new RRC common requirements for subspecialty training, development of a competency-based fellowship curriculum, competency-based assessment tools, and pediatric subspecialty fellows as teachers. Attendees are encouraged to bring tools and ideas for discussion and development. Attendees should leave with useful materials to bring back to their home programs.

  • Overview
    Susan Guralnick, Stony Brook University Medical Center, Stony Brook, NY
    Joseph Gilhooly, Oregon Health & Science University, Portland, OR

  • A Brave New World! New Common Requirements for Subspecialty Training—Implementing the Competencies
    Carol Carraccio, Professor of Pediatrics and Associate Chair for Education, University of Maryland School of Medicine, Baltimore, MD

  • "Survivor ACGME"—Fellowship Competencies in Action
    Joseph Gilhooly, Oregon Health & Science University, Portland, OR
    John D. Mahan, Children’s Hospital, The Ohio State University, Columbus, OH

  • Turning to Fellows as Teachers: From Curricula to Evaluation
    Nancy D. Spector, St. Christopher's Hospital for Children, Philadelphia, PA
    Susan Guralnick, Stony Brook University Medical Center, Stony Brook, NY

Sponsored jointly by the Association of Pediatric Program Directors and the Pediatric Academic Societies

Supported by an unrestricted educational grant from Dey, L.P.

3:15pm–5:15pm
2725—Integrating Genetic Susceptibility and Environmental Influences in Pediatric Research
PAS Topic Symposium
Room 2008, Moscone West
Chair: Bruce P. Lanphear, Cincinnati Children's Environmental Health Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

Target Audience: A broad pediatric audience with the goal of promoting interdisciplinary understanding and greater integration of genetic and environmental research.

Asthma, preterm birth, ADHD and other prevalent pediatric conditions are widely recognized to result from interactions of environmental influences and genetic susceptibility. Tremendous progress has been made in measuring both environmental and genetic risk factors. Increasingly, researchers are moving beyond ecological methods (e.g., questionnaires, air monitoring) to directly measure in humans hundreds of environmental chemicals, from nicotine to metals to DDT and phthalates. Similarly, unprecedented innovation has led rapidly to high-throughput methods that assess DNA variation across large cohorts. New interdisciplinary collaborations that integrate state of the art approaches to both environmental and genetic influences should greatly improve our ability to predict and prevent disease and disability. Such studies will be critical for understanding mechanistic pathways, defining susceptible subpopulations and developing effective interventions. This session will provide an overview of gene–environment research, describe recent advances in biomarkers of environmental exposure and review new methods for measuring genetic variability.

  • Gene–Environment Interaction in Common Pediatric Conditions: Conceptual Overview and Recent Evidence
    Robert S. Kahn, Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH

  • Advances in Biomarkers of Environmental Exposure in Pediatric Research
    Bruce P. Lanphear, Cincinnati Children's Environmental Health Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

  • Measuring Genetic Susceptibility to the Environment: Study Designs and Genotyping Methods
    Robert O. Wright, Harvard Children's Environmental Health Center, Boston Children's Hospital and the Harvard School of Public Health, Boston, MA

3:15pm–5:15pm
2730—Mechanisms of Hypertension in the Molecular Era
PAS/ASPN/IPHA/LWPES Topic Symposium
Room 2003-2005, Moscone West
Chairs: Bruce Z. Morgenstern, Phoenix Children's Hospital, Phoenix, AZ; and Julie R. Ingelfinger, Massachusetts General Hospital, Boston, MA

Target Audience: General pediatricians, nephrologists, endocrinologists and neonatologists.

Our understanding of the pathophysiology of hypertension has been changing rapidly due to advances in molecular genetics, most notably the identification of several single-gene defects that cause hypertension. This session will update participants on the latest advances in our knowledge of molecular mechanisms of a variety of forms of hypertension.

  • Role of Dopamine Receptors
    Pedro A. Jose, Georgetown University Medical Center, Washington, DC

  • Perinatal Programming and the Development of Hypertension
    Lori Woods, Oregon Health & Science University, Portland, OR

  • Low Renin Hypertension in Childhood
    Maria I. New, Mount Sinai School of Medicine, New York, NY

  • WNK Kinases and Blood Pressure Regulation
    Richard Lifton, Yale University School of Medicine, New Haven, CT

Sponsored jointly by the American Society of Pediatric Nephrology, the International Pediatric Hypertension Association, the Lawson Wilkins Pediatric Endocrine Society and the Pediatric Academic Societies

3:15pm–5:15pm
2751—Neonatal Fetal Nutrition and Metabolism I
PAS Platform Session
Room 3022, Moscone West
Chairs: David H. Adamkin and Ronnie Guillet

3:15pm–5:15pm
2753—Neonatal Infectious Diseases
PAS/PIDS Poster Symposium
Room 3003-3005, Moscone West
Chairs: Deborah A. Lewinsohn and John V. Williams

3:15pm–5:15pm
2755—Neonatal Medicine: Clinical Trials I
PAS Platform Session
Room 3002-3008, Moscone West
Chairs: Namasivayam Ambalavanan and Reese H. Clark

3:15pm–5:15pm
2757—Nutrition and Behavior
PAS Poster Symposium
Room 3024, Moscone West
Chairs: Conrad R. Cole and Timothy A. Sentongo

3:15pm–5:15pm
2768—So You Want To Do International Research?
PAS Educational Workshop
Golden Gate Hall B1, SF Marriott
Leader: Linda Wright, Rockville, MD; Co-leaders: Jose Belizan, Waldemar Carlo, Jeanne McDermott, Elizabeth McClure and Cyril Engmann

Target Audience: Trainees, fellows, junior faculty, and mid-level faculty.

Almost all (99%) of maternal and infant deaths worldwide occur in low and middle-income countries. Conducting research in these countries has many rewards and challenges, which are often daunting for investigators trying to apply for NIH support. This workshop will describe the process of applying for research support from NIH, how review is done and funding decisions made, how to enhance the likelihood of success and NIH's priorities for research. We will also discuss the design and conduct of studies in these settings, how to identify appropriate partner countries and collaborate with local investigators and government organizations as well as how to address three important areas for international research, strengthening local research capacity, scaling up proven interventions, and facilitating sustainability.

Objectives:

– To increase participants understanding of issues related to the design and implementation of clinical trials in low and middle-income countries
– To increase participants skills in writing a protocol for research in another country
– To increase participants knowledge of funding opportunities for research in low and middle-income countries

Format: The format will be didactic presentations with extensive question-and-answer session.

3:45pm–5:15pm
2790A—Hyperthyroidism
LWPES Workshop
Room 3000, Moscone West
Chair: Scott A. Rivkees, Yale School of Medicine, New Haven, CT

Target Audience: Generalists.

Much controversy exists about the most effective and safest treatments for hyperthyroidism in children. This workshop will clarify some of the newer evidence based approaches to the diagnosis and management of hyperthyroidism, with a special emphasis on radioactive ablation.

  • Hyperthyroidism
    Scott A. Rivkees, Yale School of Medicine, New Haven, CT

3:45pm–5:15pm
2795A—Neonatal Diabetes
LWPES Workshop
Room 3001, Moscone West
Chair: Mark A. Sperling, Children's Hospital of Pittsburgh, Pittsburgh, PA

Target Audience: Endocrinologists and neonatologists.

Over the past few years much has been learned about the pathogenesis of neonatal diabetes. This workshop will impart knowledge on important considerations in the diagnosis and work-up of this rare condition.

4:00pm–7:30pm
Commercial Exhibits Open and Posters Available for Viewing
PAS Exhibits
Levels 1 and 2, Moscone West

Posters Available for Viewing: 4:00pm–7:30pm
Author Attendance: 5:15pm–7:15pm

Level 1:
– Developmental Biology
– Endocrinology
– Hematology–Oncology
– Neonatal Infectious Diseases
– Neonatology
– Nephrology

Level 2:
– Cardiology
– Developmental–Behavioral Pediatrics
– General Pediatrics
– Medical Education
– Neurology

5:15pm–7:15pm
Poster Session I and PAS Opening Reception
PAS Poster Session
Levels 1 and 2, Moscone West

Posters Available for Viewing: 4:00pm–7:30pm
Author Attendance: 5:15pm–7:15pm

Level 1:
– Developmental Biology
– Endocrinology
– Hematology–Oncology
– Neonatal Infectious Diseases
– Neonatology
– Nephrology

Level 2:
– Cardiology
– Developmental–Behavioral Pediatrics
– General Pediatrics
– Medical Education
– Neurology

Includes:

  • SPR Student Research Award: Resuscitation of Non-Viable Infants: Will Neonatologists' Practice Change After the Born-Alive Infant Protection Act?
    Mya Sendowski, University of California, San Francisco, CA

7:15pm–8:30pm
2960A—Neonatal Hemodynamics Club
Club
Golden Gate Hall A1-3, SF Marriott

  • Relative Adrenal Insufficiency in the Preterm and Term Infant
    Kristi L. Watterberg, University of New Mexico Health Sciences Center, Albuquerque, NM

  • Cardiac Function and Its Relationship to Serum Cortisol, Inflammation, Pulmonary Acuity and Hydrocortisone Therapy in Sick ELBW Infants
    Cynthia H. Cole, Harvard Medical School, Boston, MA

  • Discussion

Istvan Seri, MD, PhD
Children’s Hospital Los Angeles, University of Southern California
Phone: 323-669-5932
Email: iseri@chla.usc.edu

Supported by an unrestricted educational grant from Dey LP


Sunday, April 30

6:00am–8:00am
Surfactant Therapy—Where Are We and Where Do We Go from Here?
PAS Industry Sponsored Symposium
Yerba Buena Gardens Salon 8, SF Marriott

Target Audience: Neonatologists.

Respiratory distress syndrome (RDS) results from insufficient levels of endogenous surfactant. Surfactant therapy, when used as treatment or prophylaxis, significantly reduces morbidity and mortality. New synthetic protein-containing products promise to emerge soon as a viable therapeutic strategy in the prevention of RDS. Neonatologists and other pediatric health care professionals need to have a thorough and up-to-date understanding of current and emerging products to make the most informed clinical decisions for their patients.

This symposium will focus on the current role of exogenous surfactant therapy in neonatology. Speakers will review the composition and function of this class of compounds. Faculty also will discuss the clinical status of current animal-derived and future protein-containing synthetic surfactant therapies, including comparative trials and meta-analyses, as well as studies of various ventilation strategies in conjunction with surfactant therapy. Additionally, speakers will describe potential new applications of surfactant therapy.

For information please contact: (Please note that pre-registration is not required)
Danielle Krasny 
Phone: (215) 860-2202 
Email: danielle.krasny@thomson.com

This activity is jointly sponsored by Thomson Professional Postgraduate Service and Thomson Scientific Connexions

Supported by a grant from Discovery Laboratories, Inc.

7:00am–8:00am
3045—Neonatology:
There Are Many Ways to Get to Rome (or Omaha or…)
PAS Meet the Professor
Yerba Buena Gardens Salon 10, SF Marriott

This interactive session will explore the proposition that the route that one chooses to success in an academic environment is less important than the way one makes the journey. The important principles of making the trip are simple. They are easier to measure than to master.

8:00am–10:00am
3110—Probiotics in Necrotizing Enterocolitis—Their Clinical Effect and Possible Mechanisms
PAS/ASPR/JPS/NASPGHAN Topic Symposium
Room 3003-3005, Moscone West
Chairs: W. Allan Walker, Harvard Medical School, Boston, MA; and Yuichiro Yamashiro, Juntendo University School of Medicine, Tokyo, Japan

Target Audience: Neonatologists, gastroenterologists, pediatric surgeons, NICU nurses and bacteriologists in perinatal medicine.

Necrotizing enterocolitis (NEC) is a serious gastrointestinal disease seen predominantly in very low birth weight (VLBW) and extremely low birth weight (ELBW) infants. NEC is probably a complex, multifactorial disease. Currently, the precise pathogenic mechanisms remain to be elucidated; however, clinical use of probiotics has been reported to be useful for preventing NEC development in VLBW and ELBW infants. This session will provide us the current knowledge about the role of probiotics in the management of NEC.

  • Fifteen-Year's Experience of Early Administration of Bifidobacterium Breve to Preterm Infants
    H. Kitajima, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan

  • Oral Probiotics Reduces Incidence of NEC in VLBW Infants
    H. C. Lin, China Medical University, Taichung, Taiwan

  • Effects of Probiotics on the Immunological Development and Short Chain Fatty Acids in ELBW and VLBW Infants
    Yoshikazu Ohtsuka, Juntendo University School of Medicine, Bunkyo-ku, Japan

  • Possible Role of Probiotic Supplementation for Prevention from NEC
    Michael S. Caplan, Northwestern University, Evanston, IL

Sponsored jointly by the Asian Society for Pediatric Research; Japan Pediatric Society; North American Society for Pediatric Gastroenterology, Hepatology & Nutrition and the Pediatric Academic Societies

8:00am–10:00am
3125—Developmental Origins of Adult Disease—Metabolism
PAS Platform Session
Room 3010-3012, Moscone West
Chairs: William W. Hay and Rebecca A. Simmons

8:00am–10:00am
3153—Late-Breaker Abstract Session I: Clinical Trials in Neonatology
PAS Platform Session
Room 3022-3024, Moscone West Convention Center
Chairs: Lucky Jain and Robin H. Steinhorn

The "Late-Breaker" sessions will include reports on clinical trials and other important and significant pediatric research, which might not have been ready for reporting at the time of the winter abstract deadline. There are two sessions during the meeting. Session II is on Monday, May 1, from 10:15am to 12:15pm. The sessions will include presentations in the areas of noenatology, basic science and clinical research in several clinical areas. Please be sure to review the content so you don't miss these very special sessions!

The abstracts selected for this session were not available at press time, but are included as a separate piece with this program, onsite from the Information Desk on Level 1 of Moscone West, and are also posted on the PAS website at www.pas-meeting.org (after April 1).

10:15am–12:00pm
3350—APS Presidential Plenary and Awards
APS Presidential Plenary
Room 3002-3008, Moscone West
Chair: David K. Stevenson, Stanford University School of Medicine, Palo Alto, CA

*The Joseph W. St. Geme, Jr. Leadership Award is presented by the Federation of Pediatric Organizations on behalf of the Ambulatory Pediatric Association, American Academy of Pediatrics, American Board of Pediatrics, American Pediatric Society, Association of Medical School Pediatric Department Chairmen, Association of Pediatric Program Directors and Society for Pediatric Research.

  • 2006 APS Presidential Address
    David K. Stevenson, Harold K. Faber Professor of Pediatrics, Vice Dean and Senior Associate Dean for Academic Affairs, Stanford University School of Medicine; Director, Charles B. and Ann L. Johnson Center for Pregnancy and Newborn Services; Chief, Division of Neonatal and Developmental Medicine, Lucile Packard Children's Hospital at Stanford, Palo Alto, CA

  • New Member Outstanding Science Award—Epithelial Branching and the Origins of Kidney Malformation
    Norman D. Rosenblum, Professor of Paediatrics and Canada Research Chair in Developmental Nephrology, Division of Nephrology & Program in Developmental Biology, The Hospital for Sick Children, Toronto, Ontario, Canada

    • Introduction, John Howland Awardee
      Frederick J. Suchy, Herbert H. Lehman Professor of Pediatrics and Chair, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY

  • 54th Annual John Howland Award
    Kurt Hirschhorn, Professor of Pediatrics, Human Genetics and Medicine, Chairman Emeritus, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY

    • Introduction, Joseph W. St. Geme, Jr. Leadership Award
      Carol Carraccio, Professor of Pediatrics and Associate Chair for Education, University of Maryland School of Medicine, Baltimore, MD

  • Joseph W. St. Geme, Jr. Leadership Award*
    Carol D. Berkowitz, Professor of Clinical Pediatrics, David Geffen School of Medicine at UCLA, Torrance, CA

11:00am–4:00pm
Commercial Exhibits Open and Posters Available for Viewing
PAS Exhibits
Levels 1 and 2, Moscone West

Posters Available for Viewing: 11:00am–4:00pm
Author Attendance: 12:00pm–2:00pm

Level 1:
– Allergy, Immunology and Rheumatology
– Developmental-Behavioral Pediatrics
– Endocrinology
– Infectious Diseases
– General Pediatrics
– Hematology–Oncology

Level 2: 
– Cardiology
– Neonatal Neurology
– Neonatology

12:00pm–1:30pm
3440A—Perinatal Brain Club
Hypothermia as a Neuroprotective Strategy in Term Infants
Club
Room 3022-3024, Moscone West

  • Introduction
    Jeffrey M. Perlman, Weill Cornell Medical College, New York, NY

  • Hypothermia and Neuroprotection—Future Strategies Based on Experimental Observations
    Marianne Thoresen, University of Bristol, Bristol, England, UK

  • Hypothermia as a Neuroprotective Strategy—Translating Science into Clinical Practice: What Are the Hidden Obstacles?
    Lu-Ann Papile, University of New Mexico Health Science Center, Albuquerque, New Mexico

  • Discussion 

Contact for information:
Jeff Perlman, MD
Weill Cornell Medical College
Phone: 212-746-3533
Email: jmp2007@med.cornell.edu

12:00pm–2:00pm
Poster Session II
PAS Poster Session
Levels 1 and 2, Moscone West

Posters Available for Viewing: 11:00am–4:00pm
Author Attendance: 12:00pm–2:00pm

Level 1:
– Allergy, Immunology and Rheumatology
– Developmental-Behavioral Pediatrics
– Endocrinology
– Infectious Diseases
– General Pediatrics
– Hematology–Oncology

Level 2:

– Cardiology
– Neonatal Neurology
– Neonatology

Includes: 

  • SPR Fellow's Basic Research Award: Myopalladin Mutations and Inherited Cardiomyopathies
    Enkhsaikhan Purevjav, Baylor College of Medicine, Houston, TX

  • SPR Clinical Research Award: Accelerated Development in the Visual Areas of Preterm Infants? A Voxel-Based Morphometry Study on Diffusion Tensor MR Imaging (DTI)
    Maria Miranda, Copenhagen University Hospital, Hvidovre, Denmark

  • SPR Fellow's Clinical Research Award: Novel Genotyping Technology To Classify Childhood Leukemia
    Joshua D. Schiffman, Stanford University, Palo Alto, CA

  • SPR House Officer Research Award: Erythropoietin Protein Expression in the Developing Human Eye
    Shrena Patel, University of New Mexico, Albuquerque, NM

2:00pm–4:00pm
3705—Infections at the Maternal–Placental–Fetal Interface: Immunopathogenesis of Group B Streptococcus, Listeria monocytogenes and Cytomegalovirus
PAS/PIDS Topic Symposium
Room 3022-3024, Moscone West
Chairs: John R. Schreiber, University of Minnesota Medical School and University of Minnesota Children's Hospital/Fairview, Minneapolis, MN; and Robert F. Pass, University of Alabama at Birmingham, Birmingham, AL

Target Audience: Neonatologists, infectious disease specialists, immunologists, developmental biologists and general pediatricians.

Infections in newborns commonly result from acquisition either during the delivery process or transplacentally. The host and pathogen factors that contribute to acquisition of infections at the maternal–placental–fetal interface are poorly understood. This symposium will review the basic science and immunopathogenesis of three diverse pathogens that all share the ability to cause infections at the placental level: cytomegalovirus, group B streptococcus, and Listeria monocytogenes.

  • Intrauterine Cytomegalovirus Infection, Transplacental Spread of Virus and Control by Maternal Immunity
    Lenore Pereira, University of California San Francisco, San Francisco, CA

  • Host and Bacterial Factors in Invasive Group B Streptococcal Infection
    Craig E. Rubens, University of Washington, Seattle, WA

  • Listeriosis in the Pregnant Guinea Pig: A Model of Vertical Transmission
    Daniel A. Portnoy, University of California Berkeley, Berkeley, CA

  • Discussion

Sponsored jointly by the Pediatric Infectious Diseases Society and the Pediatric Academic Societies

2:00pm–4:00pm
3718—Fetal Origins of Adult Disease
PAS Poster Symposium
Room 3001, Moscone West
Chairs: David W. Boyle and Jeffrey L. Segar

2:00pm–4:00pm
3722—Neonatal Lung Inflammation: Mechanisms and Clinical Implications
PAS Platform Session
Room 3014, Moscone West
Chairs: Rose M. Viscardi and Stephen E. Welty

Supported by an unrestricted educational grant from Dey, L.P.

2:00pm–4:00pm
3724—Neonatal Medicine: Clinical Trials II
PAS Platform Session
Room 3002-3008, Moscone West
Chairs: Ricki F. Goldstein and Robert M. Ward

2:00pm–4:00pm
3726—Neonatal Neurology: MRI and aEEG in the NICU
PAS Poster Symposium
Room 3020, Moscone West
Chairs: Linda S. de Vries and Terrie E. Inder

2:00pm–4:00pm
3732—Pulmonary and Cardiac Development: Transcriptional Control and Stem Cells
PAS Platform Session
Room 2004, Moscone West
Chairs: Lawrence M. Nogee and George A. Porter

Includes:

  • SPR Student Research Award: Critical Requirement of C/EBP[alpha] for Lung Maturation and Function
    Prithy Martis, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

2:00pm–5:00pm
3740—AAP Presidential Plenary and First Annual Silverman Lecture
AAP Presidential Plenary
Room 3007-3011, Moscone West
Chair: Errol R. Alden, American Academy of Pediatrics, Elk Grove Village, IL

Target Audience: Scientists and clinicians interested in the translation of research and evidence-based principles into health policy and practice.

  • AAP Presidential Address
    Eileen M. Ouellette, President, American Academy of Pediatrics, Elk Grove Village, IL

  • The Community Pediatrics Training Initiative: Quality Resident Education in Community Pediatrics
    Jeffrey M. Kaczorowski, University of Rochester, Strong Memorial Hospital, Rochester, NY

  • The Scientific Underpinnings of Preventive Services for Children: The Bright Futures Project
    Paula M. Duncan, University of Vermont, Burlington, VT

  • The Evidence Base Underlying Pay-for-Performance Initiatives
    Paul V. Miles, The American Board of Pediatrics, Chapel Hill, NC

  • First Annual William A. Silverman MD Lecture:
    From Disasters to Triumphs—Lessons Learned in the Evolution of Neonatology as a Subspecialty
    Avroy A. Fanaroff, Case Western Reserve University School of Medicine, Cleveland, OH

    • Introduction
      Gerald B. Merenstein, University of Colorado School of Medicine, Aurora, CO

The Silverman Lecture is sponsored by the AAP Section on Perinatal Pediatrics

2:00pm–5:00pm
3765—High-Fidelity Pediatric Simulation: Setting a National Human Performance and Patient Safety Research and Training Agenda
PAS Educational Workshop
Yerba Buena Gardens Salon 2, SF Marriott
Leader: Louis Halamek, Palo Alto, CA; Co-leaders: Mary Patterson, Joseph Lopreiato

Target Audience: Trainees, fellows, junior faculty, and mid-level faculty, senior faculty.