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Saturday, May 01, 2010 8:00 AM - 10:00 AM |
| Session Number: 1110 |
| Critical Care Nephrology: New Concepts in Sepsis |
| PAS Topic Symposium |
| Vancouver Convention Centre ~ 223/224 |
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| Target Audience: Clinicians and researchers who wish to understand some updated concepts in the biology of sepsis and associated AKI, newer tools potentially available for use in determining outcomes, and treating patients in both the acute and chronic settings. |
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| Objectives:
- Understand the current status of biological underpinnings of sepsis and how this may potentially guide future therapeutics[br]- Understand the future role of translational medicine and how it may affect decisions to treat and implications on outcomes[br]- Appreciate the central role that Sepsis associated Acute Kidney Injury plays in influencing morbidity and mortality in terms of cross-talk with other organ systems and what impact this has on care beyond the ICU environment |
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| Chairs: Gail M. Annich, University of Michigan, Ann Arbor, MI and Annabelle Chua, Texas Children[apos]s Hospital- Baylor College of Medicine, Houston, TX |
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| Sepsis and AKI related sepsis are responsible for a significant degree of morbidity and mortality in the pediatric population. Treatment protocols and improved outcomes remain elusive. Currently these entities are becoming areas of in-depth investigation in terms of basic patho-physiology and clinical care pathways. The use of translational research methodologies to better define sepsis and its sequelae, predict outcomes and provide treatment options are also being intensively studied. The first speaker will present a state of the art in terms of our current understanding of the basic science of sepsis. The second speaker will present information on current biological profiling methods in terms of predicting patient outcomes. The third will provide an update on the specific entity of sepsis related AKI- clinical outcomes and approaches. The fourth will provide a unique look at the long-term outcomes of patients with sepsis related AKI after PICU care. |
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Gail M. Annich
University of Michigan, Ann Arbor, MI |
| 8:00 AM - |
AKI and Sepsis [ndash] From Bench to Bedside and Beyond
Annabelle Chua
Texas Children[apos]s Hospital- Baylor College of Medicine, Houston, TX |
| 8:05 AM - |
The Biology of Sepsis
Thomas P. Shanley
University of Michigan, Ann Arbor, MI |
| 8:30 AM - |
Transcriptional Profiling in Sepsis
Hector R. Wong
Cincinnati Children[apos]s Hospital Medical Center, Cincinnati, OH |
| 8:55 AM - |
Sepsis-Associated AKI
David J. Askenazi
University of Alabama, Birmingham, AL |
| 9:20 AM - |
Renal Rehabilitation: After ICU Care for Sepsis-Associated AKI
Neesh Pannu
University of Alberta, Edmonton, AB, Canada |
| 9:45 AM - |
Discussion
Discussion
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| Program developed by the American Society of Pediatric Nephrology, Pediatric Infectious Diseases Society and the Pediatric Academic Societies |
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