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1998
Pediatric Academic Societies' Annual Meeting
xxMay 1-5,
1998 - New Orleans Convention Center |
STATE-OF-THE-ART
PLENARY
Asthma *- Friday, May 1, 3:15 pm -
4:45 pm
Chair: Michael M. Grunstein, Children’s
Hospital of Philadelphia, University of Pennsylvania
The alarming
increases in the prevalence, morbidity, and
age-adjusted mortality rates in children with asthma
underscore the crucial need to gain a better
understanding of the pathobiology and management of
this most chronic disease in children. This plenary
session addresses these issues in State-of-the Art
presentations.
Michael M.
Grunstein, Children’s Hospital of
Philadelphia, University of Pennsylvania
New Concepts on the Pathogenesis of Asthma
Stanley J.
Szefler, National Jewish Medical and
Research Center
New Concepts in the Pharmacological
Management of Childhood Asthma
Tracy A. Lieu,
Division of Research, Kaiser Permanente
Asthma Health Services Research: The New Frontier
Brain Metabolism and
Injury - Friday,
May 1, 3:15 pm - 4:45 pm
Chair: Donna Ferriero, University of
California San Francisco
Hypoxic-ischemic
brain injury remains a major cause of mortality and
mobidity in the neonatal period. In recent years
basic research has raised the possibility that damage
may be mitigated by modifying the normal response to
injury or by promoting healing from neuronal stem
cells. A variety of new therapies may soon be ready
for clinical trials. This session will focus on the
accurate diagnosis and grading of hypoxic-ischemic
injury and discuss new concepts in the mechanisms of
both injury and recovery.
Anthony James
Barkovich, University of California, San
Francisco
Magnetic Resonance of the Brain in Asphyxiated
Neonates
Evan Y. Snyder,
Harvard Medical School and Childrens’
Hospital, Boston
Neutral Progenitors and Stem Cells: Developmental
Insights May Suggest New Strategies for Gene Therapy
and Repair of the Injured Newborn Brain
Donna M.
Ferriero, University of California at San
Francisco
Injury Response in the Developing Brain: OH. NO+
Cell Signaling - Monday, May 4, 12:30 pm -
2:00 pm
Chair: Michael M. Grunstein, Children’s
Hospital of Philadelphia
Emerging new
information provides evidence that a variety of
diseases in children are attributed to pertubations
in certain transmembrane signaling mechanisms
regulating cellular function. According, this plenary
session is aimed at providing a contemporary overview
of various aspects of altered transmembrane signaling
related to disease.
Andrew
Shenker, Children’s Memorial Hospital,
Northwestern University Medical School
Mutations in G protein-Coupled Pathways as a
Cause of Endocrine Disease
Garrett M.
Brodeur, Children’s Hospital of
Philadelphia, University of Pennsylvania
The Biological and Clinical Importance of TRK
Family Gene Expression and Signaling in Human
Neuroblastomas
Steven A.N.
Goldstein, Yale University School of Medicine
The Molecular Basis for Ion Channel Function and
Disease
Child Health Services
Research * - Monday, May 4, 12:30 pm - 2:00 pm
Chair: James Perrin, Massachusetts General
Hospital, Harvard Medical School
Child health
services research represents a relatively new field
for pediatric departments and investigators. As such,
the area has only recently clarified its ain
investigative activities, techniques, and links with
other disciplines: The field includes diverse areas
including outcomes research, quality assessment,
clinical effectiveness, health services utilization,
and access. This session will highlight recent
developments in health services research for children
and adolescents, data available for analysis, and the
relationship of health services research to studies
of quality.
John M.
Eisenberg, Agency for Health Care Policy and
Researh
Child Health Service Research: What is it and
what have we learned?Steven L. Gortmaker, Harvard
School of Public Health, Boston
Data Sources for Child Health Services Research
David A.
Bergman, Department of Pediatrics, Stanford
University
Practice Guidelines: Necessary but not Sufficient
to Improve Care
Fetal - Neonatal
Medicine - Sunday, May 3, 1:00 pm - 2:30 pm
Chair: Philip Shaul, University of Texas
Southwestern Medical Center
Significant
advances have been made in the diagnosis, treatment
and outcome of specific diseases of the fetus and
newborn. The speakers in this symposium will describe
some of these advances as they relate to problems
found in the separate organ systems.
Robert L.
Chevalier, University at Virginia Medical
Center
Congenital Obstructive Nephropathy: From the
Fetus to the Future
Beverly S.
Emanuel, The Children’s Hospital of
Philadelphia
From Maps to Medicine: Dissecting the Chromosome
22 Microdeletion Syndromes
David A.
Williams, Howard Hughes Medical Institute and
Indiana University School of Medicine
Biology and Clinical Use of Interleukin-11:
Implications for a New Therapy of Necrotizing
Entercolitis
Gene Therapy - Sunday, May 3, 1:00 pm -
2:30 pm
Chair: Michael Kaback, University of
California-San Diego
Sponsored
by an education grant from March of Dimes Birth
Defects Foundation
The explosion in
molecular definition of inherited pediatric disorders
of metabolism and development and delineation of gene
alterations in malignancies has provided increased
understanding of the pathogenesis of metabolic
disease, congenital malformations, and cancer.
However, specific treatment directed at the genetic
mutations or defects remains rare. The speakers in
this State of the Art symposium will focus on the
prospects for gene therapy for pediatric disorders.
Nelson A.
Wiebel, Institute for Human Gene Therapy,
Wistar Institute
A Primer of Gene Therapy Methodologies
Mark A. Kay, Division
of Medical Genetics, University of Washington
Gene Therapy for Genetic Diseases
Malcolm
Brenner, St. Jude’s Research Hospital
Public Policy Forum -
Developing Future Pediatric Academicians *- Saturday, May 2, 1:30 pm -
3:00 pm
Chair: Jimmy L. Simon, Wake
Forest University
This interactive
and provocative session is intended to explore the
issues surrounding the education and training of
pediatric researchers and will be moderated by Jimmy
Simon, M.D., chair of the Task Force on the Future of
Pediatric Education II. The panelists will address
issues concerning the research tracks for fellows
comparing those who engage in a clinical subspecialty
versus those who engage in research; the financing of
tracks for basic and clinical research; the
relationship between excellence in pediatric research
training and the health of children; the education of
pediatric health service researchers and the
obligation of the mentor, department and school to
assure that fellows receive training that is required
to make them competitive. In addition, a member of
the Louisiana Congressional delegation will be
invited for the session to discuss the role of the
government in the education and financing of
residents in this country.
Thomas Boat, Children's
Hospital Medical Center & University of
Cincinnati Colleg of Medicine
Financing Graduate Medical Education
Robert Kelch, The
University of Iowa College of Medicine
Developing Future Pediatric Academicians:
Training Physician Scientists
James M.
Perrin, Massachusetts General Hospital,
Harvard Medical School
Education of Pediatric Health Service Researchers
Christopher
Wilson, University of Washington
The obligations of the mentor, department and
school to assure that fellows receive training that
is required to make them competitive.
Telemedicine - Sunday, May 3, 1:00 pm -
2:30 pm
Chair: Michael Fordis, Baylor College of
Medicine School of Medicine
Recent advances
in telecommunications, information, and Internet
technologies are providing academicians and
practicing physicians with a new set of tools for
engaging in healthcare, clinical research, and
education at a distance. Telemedicine technologies
are providing impetus for academic centers to rethink
how they pursue their tripartite missions. In this
plenary session, existing technologies will be
presented and demonstrated, relevant obstacles and
issues including regulatory concerns will be
discussed, and a glimpse into the future will be
provided.
Michael
Fordis, Baylor College of Medicine
Reaching Beyond the Walls of Academia:
Technologies for Today and Tommorrow
David B.
Heskamp, Lockheed Martin
Virtual Sinus Surgery
Robert Waters,
Arent Fox Kintner and Plotkin
Telemedicine: The Legal and Regulatory
Environment
Ronald K.
Poropatich, Walter Reed Army Medical Center
Telemedicine: Exploring the New Frontier
Thromboembolic Disease
in Children:
A Product of Modern Technology
Monday,
May 4, 12:30 pm - 2:00 pm
Chair: Maureen Andrew, Hamilton Civic
Hospital Research Center & Alan Michelson,
University of Massachusetts Medical School
Thromboembolic
disease in children and newborns is an increasingly
frequent and serious problem. These patients have
serious underlying diseases that complicate the
diagnosis and treatment. This session will discuss
new information on the molecular causes of thrombotic
diseases in children as well as the diagnosis and
management of childhood stroke, venous thrombotic
disease and central venous line related thrombosis.
Ongoing international trials addressing these issues
will be summarized.
Edwin (Ted)
Bovill, University of Vermont College of
Medicine
Pathophysiology and Evaluation of the Hereditary
Hypercoagulable State
Patricia
Massicotte, The Hospital for Sick Children at
Toronto
Central Venous Line Thrombosis: An Epidemic in
Tertiary Care Pediatrics
Gabrielle
deVeber, Hamilton Civic Hospitals Research
Center & McMaster University
Thrombotic Stroke in Little Folks: A Diagnostic
and Therapeutic Challenge
Alan
Michelson, University of Massachusetts Medical
Center
Antithrombotic Therapy in Children
Transcription Factors
in Endocrine Development ** -
Sunday, May 3, 1:00 pm - 2:30 pm
Chair: Melvin Grumbach, University of
California, San Francisco
The program will
review the latest developments in how the endocrine
glands form, develop and function. The session will
focus on pituitary, thyroid, adrenal and gonadal
development. It is jointly sponsored with the LWPES.
John Parks, Emory
University School of Medicine
Edward R.B.
McCabe, University of California, Los Angeles
* Sponsored jointly
by the Pediatric Academic Societies
**Sponsored by the
American Pediatric Society, Society for Pediatric
Research and the Lawson Wilkins Pediatric Endocrine
Society
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