MONDAY, MAY 3 Saturday, May 1 Sunday, May 2 Tuesday, May 4

Advances in Cognitive Neurosciences (Sponsored jointly by the Pediatric Academic Societies)
Chair: Donna Ferriero, University of California, San Francisco

Cognitive disorders affecting language, learning and behavior effect a broad range of pediatric patients. Speakers in this session will address recent advances in the development and function of the fetal cortex, especially in regard to actions of steroids, insights into cognitive disorders derived from advanced neuro-imaging techniques and new methods of neuro-rehabilitation using computer technology for specifically language impaired children.

Neuroscience Based Training Ameliorates Language Impairment
Michael Merzenich, University of California, San Francisco

Neuro-imaging in Cognitive Disorders
Pauline Filipek, University of California, Irvine

Neurosteroids and Cortical Development
Synthia Mellon, University of California, San Francisco

Apoptosis
Chair: Roberta Gottlieb, Scripps Research Institute, San Diego

New discoveries in the mechanisms of programmed cell death will be reviewed. The essential nature of apoptosis in mammalian development and current and future application of these discoveries to clinical medicine will be presented.

8:00 am --- Mitochondria: Ignition Chamber for Apoptosis
Roberta Gottlieb, Scripps Research Institute, San Diego

8:40 am --- Caspases and Cell Death
Guy Salvesen, Burnham Institute, San Diego

9:40 am --- Identification of Components of the Cell Death Pathway
Vishva Dixit, Genentech, Inc., San Francisco

Topic: Infection/Inflammation and White Matter Injury – Experimental Evidence

Inflammatory Mediators and White Matter Injury- Experimental Evidence
John Barks, University of Michigan Hospital, Ann Arbor

Fetal Inflammatory Responses and MR Imaging
David Edwards, Imperial College School of Medicine, Hammersmith Hospital, London

Inflammation, Infection and CP
Karin Nelson, National Institutes of Health, Bethesda

For Further Information Contact:
Jeffrey Perlman, M.D.
Department of Pediatrics, University of Texas Southwestern Medical Center
5323 Harry Hines Blvd., Dallas, TX 75235-9063
Phone: (214) 648-2060 Fax: (214) 648-2481
E-mail: JPERLM@MEDNET.SWMED.EDU

1:15 pm – 4:30 pm ** Symposium

Topic: Molecular Epidemiology of Infectious Diseases

Progress Toward a Molecular Genetic Understanding of Serotype M1 Group A Streptococcal Epidemic Waves
James M. Musser, M.D., Ph.D., Professor of Pathology, and of Microbiology & Immunology, Baylor College of Medicine

Molecular Epidemiology of Tick-Transmitted Diseases
David H. Persing, M.D., Ph.D, Associate Professor of Laboratory Medicine and Pathology, Mayo Clinic

Pathogen Discovery and the Future of Infectious Disease Diagnostics
David A. Relman, M.D., Assistant Professor of Medicine, and of Microbiology & Immunology, Stanford University
and Staff Physician, VA Palo Alto Health Care System

Piecing Together the Influenza Puzzle: From Spanish Flu to Bird Flu
Kanta Subbarao, M.D., Chief, Molecular Genetics Section, Centers for Disease Control and Prevention

4:45 pm – 5:45 pm ** Business Meeting and Awards

7 pm ** Reception and Dinner ** Ticket/Registration Required

For Further Information Contact:

Andrea Weddle, PIDS Staff Coordinator
PIDS Headquarters, 99 Canal Center Plaza, Suite 210, Alexandria, VA 22314
Phone: (703) 299-6764 Fax: (703) 299-0204
E-Mail: aweddle@idsociety.org

1999 Confirmed Exhibitors

Matching the Drug to the Patient: Genetic, Developmental, and Environmental Effects on Drug Responses
Chair: Thomas Hazinski, Vanderbilt University Medical School, Nashville

Advances in pharmacology and genetics have increased our understanding of individual responses to drugs. In this state of the art session, three nationally recognized experts will discuss recently discovered genetic and environmental mechanisms which explain why drugs such as opiods, chemotherapeutic agents, and cisapride are effective for some patients and toxic for others.

Effects of Ethnicity on Drug Metabolism and Drug Response
Alastair JJ Wood, Vanderbilt University School of Medicine, Nashville

Cancer Pharmacogenomics: Why Chemotherapy is Like Pinball?
Fred Ledley, Variagenics, Inc., Cambridge

Drug and Environmental Effects on a Cardiac Potassium Channel Gene: The Cisapride Controversy
Tom Klitzner, Mattel Children’s Hospital, UCLA, Los Angeles

Human Genome Project: An Update
Chair: Maynard Olson, University of Washington, Seattle

This State of the Art Plenary session will focus on how molecular genetics research will be changed by the availability of the human genome complete sequence, current applications of genome technology in human clinical research, and ethical issues in genetic research in children.

How will the Sequencing of the Human Genome Change Biomedical Research?
Maynard Olson, University of Washington, Seattle

Application of Genetic Strategies and Human Genome Project Resources for the Identification of Human Disease Genes
Val C. Sheffield, Howard Hughes Medical Institute, University of Iowa, Iowa City

Genetic Testing in Children: Ethics Issues of Research and Clinical Practice
Benjamin S. Wilfond, University of Arizona, Tuscon

Report of the Task Force on the Future of Pediatric Education II
Chairs: Jimmy Simon, Wake Forest University School of Medicine, Winston-Salem
Russell W. Chesney, University of Tennessee, Memphis College of Medicine, Memphis

Sweeping societal changes (e.g. racial and ethnic diversity, single parent families, working parents, tobacco usage, firearms, violence) and changes in child health care (new vaccines, antibiotic resistance, the human genome project, psychopharmacology, diagnosis and therapy of serious conditions -acute and chronic- in an ambulatory setting) will have a vast impact on pediatric education. These changes will alter how the medical student, the pediatric resident, the subspecialty fellow, the practicing general and subspecialty pediatrician (both early and later in their careers) and other members of the child health team will be educated. This session will discuss the background of this Task Force, those recommendations that have arisen from the ongoing deliberations of the Task Force, the data gathered, the impact of the various working groups, as well as communications from public presentations and web site responses. We will specifically focus on those recommendations which are controversial or for which there is not a consensus of opinion. We will also discuss a process of implementation, evaluation and follow-up of the Task Force final recommendations. Further information is available at www.aap.org/profed/fopel.htm

Jimmy Simon, Wake Forest University School of Medicine, Winston-Salem

Russell Chesney, University of Tennessee, Memphis College of Medicine, Memphis

Errol Alden, American Academy of Pediatrics, Elk Grove Village

Posters Available for Viewing: 2:30 pm - 6:30 pm
Authors will attend posters from 4:30 pm - 6:30 pm
Commercial Exhibits: 2:30 pm - 6:30 pm

7:00 pm - 9:15 pm Annual Meeting

Neuroimaging in Neurodevelopmental Disabilities
A. James Barkovich, University of California, San Francisco

Gene Therapy in Neurodevelopmental Disabilities
Mark L. Batshaw, Children’s National Medical Center, Washington

9:15 pm – 10:00 pm Business Meeting

For Further Information Contact:

Frederick B. Palmer, MD
Director, Boling Center for Developmental Disabilities
University of Tennessee, Memphis
711 Jefferson Avenue, Memphis, TN 38105
Phone: 901-448-6512 Fax: 901-448-7097
E-mail: fpalmer@utmem1.utmem.edu

For further information contact:
Ambulatory Pediatric Association
6728 Old McLean Village Drive, McLean, VA 22101

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Last Modified: April 06, 2000