TUESDAY, MAY 4 Saturday, May 1 Sunday, May 2 Monday, May 3

For further information contact:
Ambulatory Pediatric Association
6728 Old McLean Village Drive, McLean, VA 22101

Cytokine Receptor Defects
Chair: Jennifer M. Puck, National Center for Human Genome Research, Bethesda

This topic symposium will acquaint pediatricians with this growing list of cytokine receptor defects, their clinical features, molecular bases and means of diagnosis. A portion of the session will also be devoted to an update on the status of gene therapy for one of these defects.

X-linked SCID: A Cytokine Receptor Defect as a Target for Gene Therapy
Jennifer M. Puck, National Center for Human Genome Research, Bethesda

Jak3: Role in Cytokine Signaling and the Pathogenesis of SCID
John J. O’Shea, National Institute of Arthritis, Musculoskeletal and Skin Diseases, Bethesda

"Just Say No To Bugs: The Interferon Gamma Pathway"
Steven M. Holland, Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, NIH, Bethesda

1999 Confirmed Exhibitors

Fetal and Neonatal Medicine: Control and Disorders of Lung Growth
Chair: David Carlton, University of Utah, Salt Lake City

Abnormalities in the growth and development of the fetal lung and the fetal pulmonary vasculature remain major causes of neonatal mortality and morbidity. Pulmonary hypoplasia is found in as many as 20% of all neonatal autopsies. Speakers in this session will review the relationship between fetal lung expansion and lung growth, the embryology and pathogenesis of congenital diaphragmatic (a major cause of fatal lung hypoplasia), and factors important in postnatal remodeling of abnormal pulmonary vasculature.

Fetal Lung Development: Roles of Mechanical and Metabolic Factors
Richard Harding, Monash University, Melbourne, Australia

Pathogenesis of Experimental Diaphragmatic Hernia
John Greer, University of Alberta, Edmonton

Developmental Changes in the Pulmonary Vascular Response to Injury
Kurt Stenmark, University of Colorado Health Science Center, Denver

Molecular Pathogenesis of Infectious Diseases
Chair: Mike Tosi, Mount Sinai Medical Center, New York

The diversity of microorganisms, from prions to bacteria to yeast, and the role they play at the molecular and biochemical level in the pathogenesis of a variety of infectious diseases will be presented by three world-renowned speakers, with unsurpassable expertise in their field.

Role of Prions in the Pathogenesis of the Spongiform Encephalopathies
Fred E. Cohen, University of California, San Francisco

Molecular Pathogenesis of Salmonella Infections
Samuel I. Miller, University of Washington, Seattle

Molecular Pathogenesis of Candida Infections
Margaret K. Hostetter, Child Health Research Center, Yale University, New Haven

Posters Available for Viewing: 10 am - 2:30 pm
Authors will attend posters from 1 pm - 2:30 pm
Commercial Exhibits: 10 am - 2:30 pm

A separate registration is required for APA Workshops and Special Interest Groups and can be requested directly from the APA National office.

WORKSHOPS

19. Evidence-Based Medicine – The Tools Needed To Practice 21^st Century Medicine
20. Keep ‘Em Awake In Conference
21. Developing A Computer-Based Education Station
22. Management 101: The Skills You Need When Asked To Be The "Medical Director"
23. Urine Testing And Urinary Tract Infections In The Pros Febrile Infant Study: An Adventure In Interactive Data Analysis
24. Computerized Monitoring Of Education Programs
25. Case Writing 101: Fundamentals Of Developing A Case Based Curriculum
26. Training Residents And Providers To Effectively Manage Interpreted Medical Encounters

SPECIAL INTEREST GROUPS

The APA Special Interest Groups are informal sessions organized around a specific area of interest in general pediatrics. The sessions range in format from informal discussion to guest speakers to research presentations.

A separate registration is required for APA Special Interest Groups.

Controversies in Prehospital EMS for Children*
Chair: Gary R. Fleisher, Children’s Hospital, Boston

Each year in the United States, in the prehospital arena, hundreds of thousands of healthcare workers provide services to millions of children at a cost of billions of dollars. Most members of the medical community, as well as the lay public, assume that these dramatic interventions, accompanied by the wail of sirens and the whirl of helicopter rotors, represent part of an established continuum of medical care for the benefit of children. On closer examination, however, this particular intervention has generally not been delivered under pediatric supervision, has seldom been rigorously studied, and has often been demonstrated to have no beneficial, or even a detrimental, effect. In this session, the speakers will provide an overview of the data behind the mayhem, with specific emphasis on basic therapies: airway management, intravenous access, and cervical spine immobilization. Formal presentations will be followed by an interactive discussion. The goals of the discussion will be to: (a) establish, when sufficient information exists, which approaches are helpful and which are harmful; (b) increase the awareness among physicians of the limitations of prehospital care for children; (c) encourage involvement of pediatricians in setting policies for the treatment of children; and (4) identify areas for further investigation.

The Lack of Meaningful Research in Emergency Medical Services
Michael Callaham, University of California, San Francisco

Endotracheal Intubation of Children
Marianne Gausche, Harbor-UCLA Medical Center, Torance

Cervical Spine Immobilization
Mark Ralston, Children’s Hospital, Denver

Intravenous Access and Fluid Administration
Stephen Teach, Children’s National Medical Center, Washington, DC

Controversies in Neonatology**
Chair: F. Sessions Cole, Washington University School of Medicine, St. Louis and William J. Keenan, St. Louis University

This session will focus on a discussion of new or evolving therapies for the newborn infant, ventilatory strategies and brain hypothermia.
** Sponsored jointly by the American Pediatric Society, Society for Pediatric Research, and the American Academy of Pediatrics

4:45 pm --- Interpreting Ventilatory Strategies - Which Strategy for Which Infant?
Alan H. Jobe, Children's Hospital Medical Center, Cincinnati, Ohio

5:45 pm --- Moderate Hypothermia as a Brain Rescue Therapy After Perinatal Asphyxia
David Edwards, Imperial College School, Hammersmith Hospital, London

Controversies in Otitis Media*
Chair: Kathi J. Kemper, Center for Holistic Pediatric Education & Research, Boston

Panelists will address current controversies in the management and long-term outcome of otitis media: to treat with antibiotics or not? And does it make any difference in the long term anyway?

Acute Otitis Media Is a Treatable Infectious Disease
Jerome Klein, Boston Medical Center and Boston University School of Medicine

"To Treat or Not to Treat. That is the Question"
Mike Marcy, Kaiser Foundation Hospital, Panorama City, CA

Early-Life Otitis Media in Relation to Later Development: Preliminary Findings from the Pittsburgh Study
Jack L. Paradise, University of Pittsburgh School of Medicine, Children’s Hospital of Pittsburgh

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Last Modified: April 06, 2000