Saturday, April 28 - Tuesday, May 1, 2001
Baltimore Convention Center

Jointly sponsored by the
American Pediatric Society, Society for Pediatric Research,
and Ambulatory Pediatric Association

In cooperation with
The Center for Continuing Education,
Tulane University Medical Center

 

 Expanded schedules for:
  Sunday, 4/29
 
Monday, 4/30
 
Tuesday, 5/1

  Schedule-at-a-Glance
 Affiliated Societies and Club Schedules

SATURDAY, APRIL 28

 

 

ALL DAY
AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY
ASSOCIATION OF PEDIATRIC PROGRAM DIRECTORS

8:00am - 10:00am
EDUCATIONAL SEMINARS

Requires advance enrollment

ES01 Abstract Preparation and Presentation
The core of the academic meeting is the dissemination of new information through abstracts. This session will provide the young investigator with an approach to the preparation and presentation of abstracts. Innovative science requires crafting an innovative abstract to assure program selection. Points concerning abstract presentation to enhance acceptance and the dos and don’ts of platform and poster presentations will be presented in depth.
Rebecca A. Simmons, Assistant Professor of Pediatrics, University of Pennsylvania, Children’s Hospital, Philadelphia, PA and Edward S. Ogata, Chief Medical Officer, Children’s Memorial Hospital, Chicago, IL

ES02 Applying for Research Grants
In the current climate of funding opportunities, the ability to successfully obtain extramural support involves applying for grants that are appropriate for an investigator’s career stage and drafting a clear and focused application. In this session, we will discuss career-stage-appropriate funding opportunities from the NIH and other agencies. We will also address how to write a grant application, focusing on strategies with proven success. The working of NIH study sections will be reviewed along with how to best address the concerns of review panels. We will also focus on how to obtain funding for fellowship postdoctoral training and early stages of an academic career.
Pedro A. Jose, Professor of Pediatrics and Physiology and Biophysics Georgetown University Medical Center, Washington, DC; Anshumali Chaudhari, Scientific Review Administrator, Experimental Cardiovascular Sciences Center for Scientific Review, NIH, Bethesda, MD and M. James Scherbenske, Renal Physiology/Cell Biology and Kidney Centers and SBIR Program Director, Bethesda, MD

ES03 Career Paths in Academic Medicine: Clinical/Resident
This session will delineate the patterns of academic clinical practice. Led by a general pediatrician and pediatric subspecialist, the session will address the following topics.
1. How do I decide if I want to pursue a career in academic medicine or in community practice?
2. Are there models of practice which allow me to combine academic medicine and community practice?
3. How do I decide if I want to become a general pediatrician or want to subspecialize?
4. What are the requirements for a career in general academic pediatrics? What for subspecialists?
5. How and when do I apply for fellowships?
6. Who in my institution can help me with these career decisions?
Judith S. Palfrey, Chief, Division of General Pediatrics, Children’s Hospital, Boston, MA

ES04 Career Pathways for Hospitalists: Options and Opportunities
Pediatric Hospitalist practice is an evolving career option that combines the excitement and stimulation of high acuity patients without the limitation of sub-specialization in a specific organ system or age group. Hospitalists provide direct patient care, perform procedures, teach, conduct research, but spend too many nights and weekends in the hospital. Hear a panel of experienced pediatric hospitalists frankly discuss their varied career tracks and current employment settings ranging from the traditional academic "ward attending" to private practitioners who cover the Ward, Neonatal ICU, Pediatric ICU, ER, Nursery, and Labor and Delivery without the benefit of housestaff. Significant time will be allowed for questions to find out if a pediatric hospitalist career is in the cards for you or those you advise.
Jack Percelay, Chairperson, AAP Provisional Section on Hospital Care and Michael Ruhlen, Section Head, Pediatrics, National Association of Inpatient Physicians

ES05 Clinical Bioethics
This seminar will encourage discussion about the omission, withdrawal, or use of treatment for fetuses and newborn infants. The principles of benevolence, non-maleficence, justice and autonomy will be briefly described and illustrated by (1) a discussion of the recent Siamese twin case in England and (2) surrogate decision making. It is hoped that these topics and their presentation will lead to a lively interactive debate.
David K. Stevenson, Harold K. Faber Professor of Pediatrics, Stanford University School of Medicine, Palo Alto, CA; Jane Battaglia, Associate Clinical Professor, Anesthesiology, Pediatrics and Preventive Medicine (Program in Health Care Ethics and Humanities), University of Colorado, Denver; Rosamond Rhodes, Director of Bioethics, Mount Sinai School of Medicine, New York; Amnon Goldworth, Senior Medical Ethicist in Residence, Lucile Salter Packard Children’s Hospital, Palo Alto, CA.

ES06 Design and Execution of Randomized Clinical Trials
Randomized controlled trials are the gold standard for determining which treatments are superior. More and more, clinicians of all specialties are demanding that randomized trials show new treatments, such as surfactant and ECMO, to be superior to current therapy (or no therapy) before the new treatments are adopted.

This workshop will cover principles of clinical trials including defining the question, assessing outcomes, defining the study and control treatments, single- versus multi-center trials, reasons for and methods of randomization, eligibility and exclusions, blinding, analysis strategies, and early stopping. The format will be didactic with extensive open discussion. Real world examples of "what can happen if you don’t watch out" will be utilized. Participants are encouraged, although not required, to bring an idea for a possible clinical trial. We will use these ideas as examples during the discussion. Statistical knowledge is definitely not required.
Mark A. Klebanoff, Director, Division of Epidemiology, Statistics and Prevention Research, NICHD, NIH, Bethesda, MD

ES07 Faculty Development and Mentoring: Career Planning for Young and Old Full-Time and Volunteer Faculty Members
The purpose of this workshop is to demonstrate a faculty development program that is tailored to the needs of individual faculty members, since mentoring should be a vital component of faculty development. An appropriate mentoring program strengthens the relationship between supervisor and faculty member and mandates that the faculty member should envision his or her career goals. Evaluation, counseling and mentoring are essential contributors to departmental esprit de corps because they convey worthiness among the faculty members. Faculty development and mentoring should be the highest priority of departmental chairmen and division heads, but has been downgraded because the mentors have been encumbered with financial responsibilities in recent years. Without a faculty development and a mentoring program, a department loses one of the foundations of an academic department. The workshop will present a faculty development program that can be used by a faculty member and his or her supervisor. For those faculty members who are not being supervised, the program can be used by the faculty member for short- and long-term planning of his or her career.
Robert L. Brent, Distinguished Professor, Louis and Bess Stein Professor of Pediatrics, Professor of Radiology, Pathology, Anatomy and Cell Biology, Emeritus Chairman of the Department of Pediatrics, Jefferson Medical College, A. I. duPont Hospital for Children, Wilmington, DE

ES08 Grantsmanship and Mock Study Section
This session will provide an overview of the federal Agency for Healthcare Research and Quality’s (AHRQ’s) research priorities and grantmaking policies and procedures—from concept development and programmatic technical assistance, to notification of award (or not), and resubmission; provide a checklist of handy tops for applicants; and entertain questions about grantsmanship. In addition, two senior health
services researchers and experienced grant reviewers will lead a lively, informative, and provocative mock study section to demonstrate how applications are reviewed and scored at AHRQ. The mock study section will use an actual, but de-identified, funded AHRQ application as a learning tool, and workshop participants will be invited to provide their own comments on the application.
Denise M. Dougherty, Senior Advisor, Child Health, Agency for Healthcare Research and Quality, Rockville, MD

ES09 How to be Successful in Academic Medicine: From the Interview to Promotion
In this interactive session, a junior faculty member along with her chairman will facilitate an active dialog from what core questions should be asked during the interview to how to maximize your chances for promotion. Many issues will be directly addressed, including: interviewing questions to ask and answers to have at the ready, salary negotiations, percent effort distribution, departmental commitment and support, faculty development programs, and identification of mentors.
Jon S. Abramson, Chairman, Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC and Shari Barkin, Assistant Professor of Pediatrics and Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC

ES10 Introductory Techniques for Pediatric Research (Session limited to 25)
This seminar will provide clinically oriented pediatricians with basic epidemiologic and analytic tools needed for the planning, design, and preliminary analysis of a clinical research project. Seminar attendees and leaders will work together to develop a research strategy that includes the development of an appropriate research hypothesis, the selection of proper outcome measures, and the type of data that should be collected. We will then undertake a preliminary organization and analysis of hypothetical data. Brief didactic interludes woven into the seminar will focus on commonly used statistical terms such as relative risks, confidence intervals, and p-values.
Kenneth C. Schoendorf, Chief, Infant and Child Health Studies, National Center for Health Statistics, CDC, Hyattsville, MD and William G. Adams, Division of General Pediatrics, Boston University School of Medicine, Boston, MA

ES11 Managing the Business of Academic Pediatrics
Career and program development in Pediatric Departments is increasingly tied to the generation of resources that support these efforts as well as cost-containment efforts. This seminar will address the application of business principles and approaches that should be useful to current directors of programs, or those who aspire to be directors, as they plan and manage these programs. Concepts to be introduced in a case discussion format include cost analyses, longitudinal budgeting, mission-based budgeting, business plan development and productivity analysis and enhancement.
Thomas F. Boat, Children’s Hospital Medical Center, Cincinnati, OH, Michael K. Farrell, Professor of Pediatrics and Chief of Staff, Children’s Hospital Medical Center, Cincinnati, OH and Lori Mackey, Director of Finance, Research Administration, Children’s Hospital Research Foundation, Cincinnati, OH

ES12 Reviewing Peer Review Manuscripts
Reviewing articles for peer-reviewed journals combines many skills, including knowledge of the area of investigation, methodology, epidemiology, statistics and the scientific context of the research being reviewed. Judging one’s peers and colleagues is difficult and represents an important aspect of the scientific method. Unfortunately, there is little "formal" teaching of this activity.
In this workshop we will review the process of peer review and discuss those areas that reviewers are usually asked to comment on, including: importance and originality; validity of data; clarity of manuscript; importance for readers; and assignment of priority. Samples of checklists that some journals provide for reviewers will be distributed and discussed. Participants will be asked to review a brief manuscript and formulate their opinions during the workshop. The manuscript and reviews will then be discussed. Finally, sample reviews will be distributed and participants will be asked to assess how helpful the review would be for both the editors as well as the authors. Areas that are most subjective, such as importance for practitioners and scientists and assigning priority will be discussed, with particular attention paid to each participant’s own biases.
There is little formal instruction in the peer-review process–an important aspect of academic medicine. This workshop should help faculties who are beginning to be peer-reviewers.
Howard Bauchner, Professor of Pediatrics and Public Health, Boston University School of Medicine, Boston, MA and Patricia Shiono, The David and Lucile Packard Foundation, Los Altos, CA

8:30am - 11:30am
MINI COURSE

Patient Safety and Quality of Care
Chairs: Charles J. Homer, National Initiative for Children’s Healthcare Quality, Boston, MA and Judith S. Shaw, University of Vermont, Burlington, VT

Patient safety and quality of care continue to loom large in our patients’ and public leaders’ views about health care. Despite widespread interest in providing safe and excellent care by clinicians, many are uncertain how to respond. This course will provide both a framework for thinking about safety and quality and up-to-date information about major initiatives affecting pediatric care. Course content will specifically include updates on government initiatives about patient safety, a national project to reduce errors in hospitals, an improvement project building on comparative data from neonatal intensive care units, and the current status of efforts at quality measurement for health care accountability.

Overview
Charles J. Homer, National Initiative for Children's Healthcare Quality, Boston, MA

Collaborative Quality Improvement for Neonatal Intensive Care
Jeffrey D. Horbar, Vermont Oxford Network, Burlington, VT

Medication Safety in Children's Hospitals
Carol Haraden, Institute for Healthcare Improvement, Boston, MA

The Child and Adolescent Health Measurement Initiative
David Bergman, Lucile Packard Children's Hospital, Palo Alto, CA

Federal Role in Safety and Quality
Lisa Simpson, Agency for Healthcare Research and Quality, Rockville, MD

Discussion
Judith S. Shaw, Director & Research Assistant, Vermont Child Health Improvement Project, University of Vermont College of Medicine, Burlington, VT, University of Vermont, Burlington, VT

Sponsored Jointly with the American Academy of Pediatrics

Also See Mini Courses 9:15am-12:00noon

8:30am - 11:30am
SPECIAL INTEREST GROUPS

AIDS/HIV
This year’s theme will be “Promoting Adherence to HIV Treatment Recommendations”.  Our Baltimore based programs will present a range of activities we have used to try to support successful adherence.  Other programs are invited to share their efforts—especially if they work!  If you are willing to present in this small group, workshop format, please email Nancy Hutton at nhutton@jhmi.edu.

Behavioral Pediatrics
Little is known about the etiology, treatment, or sequelae of infantile colic.  Research has identified potential effects that colic may have on child development, parent-child relationships and family functioning.  This year’s SIG will describe a multidisciplinary outpatient clinical model of care developed to diagnose and treat infants with crying, sleeping, feeding and associated behavior problems. Pamela  C. High, J.E. Twomey, C.F.Z. Boukydis, C. L. Miller-Loncar, V. P. Dalzell & B. M. Lester, all of Brown University School of Medicine, will present "What To Do When Colic Makes You Want To Cry: A Multi-Disciplinary Approach ".  Their treatment team is comprised of pediatricians, psychologists, and a clinical social worker. Clinical interviews, behavioral questionnaires and 24-hour infant behavior diaries are used to diagnose and to monitor treatment.  The clinical approach presented in the workshop illustrates the benefits of integrating psychological and behavioral pediatric services into a single service for infants and their families.  The presenters will describe how they examine the infant’s crying and its interrelation with feeding, sleep schedules, and parent-infant interactions.  An additional emphasis of the presentation is on treating the presenting problems and preventing future behavioral difficulties.  Data looking at a possible relationship between maternal depression and colic from a sample of 90 families with infants with excessive crying will be presented.  Data on diagnosis, treatment and outcomes from 50 infants recently referred to our clinic will be presented and 6 cases will be used to demonstrate application of this model.  An important part of the presentation will be discussion of this technique’s use in primary care settings.

Complementary and Alternative Pediatrics
Our group has planned a broad-based and provocative set of case presentations for the morning of 4/28/01, starting at 8:30 am. The format for each speaker’s 40 - minute presentation will be 10 minutes for case description, 20 minutes for background information, and 10 minutes for questioning of each speaker.

Lynnae Schwartz, M.D., a Research Fellow in the Department of Anesthesia at the NIH, will present some cases of children who were successfully treated with a combination of acupuncture and conventional anesthesiology methods. The talk’s title will be:

Complementary Interventions in Pediatric Anesthesia and Pain Control.

The second speaker, Bonnie Kaplan, PhD, a Professor of Pediatrics at the University of Calgary, has a fascinating story to tell about how a new "chelated mineral supplement successfully treats mood instability in children and adolescents".

The third speaker, Mary Jane Ott, MN, MA, RNCS, is a Complementary Care Nurse Practitioner for the Pain and Palliative Care Program of the Zakim Center for Integrated Therapies / Dana Farber Cancer Institute. She is an Adjunct Assistant Clinical Professor in the School of Nursing of Northeastern University. She will discuss some case histories which involved the utilization of the patient’s own self-regulatory resources, including imagination, in the promotion of healing in the deepest sense.

During the remaining portion of the SIG we will set up a structure for planning future programs and performing projects. Please plan to join us.

Literacy Development Programs in Primary Care
This SIG supports primary care programs to promote reading aloud and the developmental aspects of literacy, based on the Reach Out and Read (ROR) model.  The three-hour meeting will focus on sharing innovations in physician and volunteer training, program organization, fund-raising, and regionalization.  Time will be devoted to in-depth discussions of multi-cultural and multi-lingual aspects of literacy intervention, advocacy around literacy, and a review of the SIG’s multi-site research project, theBefore-and-After-Books-and-Reading (BABAR) study.  A separate training session will be offered for programs just getting started.  The SIG is coordinated by Perri Klass (BU School of Medicine and Reach Out and Read, Boston) and Robert Needlman (CWRU School of Medicine and DrSpock.com).

Pain
The focus of this year's Special Interest Group on Pediatric Pain will be on newborn pain and its long-term consequences. The program will be presented by international authorities in this area, Dr, KJS Anand of the Children's Hospital of Arkansas and Dr. Ruth Grunau of the Children's Hospital of British Columbia. The program will be as follows:
8:30 Dr. Anand - Neonatal pain and acute clinical outcomes
9:00 Discussion
9:15 Dr. Grunau - Longterm outcomes related to repetitive neonatal pain
9:50 Discussion
10:00 Dr. Anand - Evidence based guidelines for neonatal pain management
10:30 Discussion
11:00 Adjourn
All who are interested in this important and evolving area are welcome to attend and participate.

Pediatric Emergency Program Directors
The 3rd PEM Directors SIG will be meeting to discuss academic issues in education and research for enhancement of the faculty growth within the field.  One area of focus will be the mentoring of junior faculty.  There will be a discussion on developing the future PEM Directors and enhancing the longevity in the field.  Directors are encouraged to contact richard.ruddy@chmcc.org for further details.

Pediatrics for Family Practice
We have a busy agenda planned that will focus on the following areas and updates.
* Pediatric training handbook for Family Practice Residents
* SIG members have established that there is no widely used resource for the Pediatric component of Family Practice Residency. A handbook developed by the York Hospital Family Practice Residency (the Reilly Handbook) was reviewed. SIG members agreed that this resource would provide a good starting point and several members agreed to work on revisions. Efforts to develop a CD ROM format were also initiated. Our goal is to develop a resource that will have broad based appeal to Family Practice Residency programs across the country
* Competency based questionnaire
* As an adjunct to the handbook, members felt it would helpful to have coordinated questions to help focus pediatric learning. Several members agreed to contribute questions. How is pediatric training addressed in Family Practice Residencies? This question was last addressed in a 1992 article by published by Baldour and Luckman. SIG members felt it would be useful to conduct a similar survey of current Family Practice programs
* Annual review of Pediatrics Guidelines for Family Practice residents
* New members in particular have found this discussion useful in terms of providing a foundation for pediatric learning objectives

Serving the Underserved
The Serving the Underserved (STUS) SIG meeting will build on the momentum of last year’s meeting and will include:
* Research/program evaluation in the STUS arena. We will highlight several successful STUS community-based projects with a special emphasis on successful program evaluation. Presenters will highlight lessons learned and academic areas to be advanced in this area. Discussants will review related resources including the AAP Center for Child Health Research and the PROS Network.
* STUS curriculum development. There has been a lot of progress with the STUS SIG web-based curriculum over the last year. We will discuss this project and other curriculum development advances in the STUS field.
* Community and the underserved. We will follow up last year’s program with a discussion of the progress being made in improving care and education in the community. Discussants from the Dyson Initiative and CATCH will be included.
* Legislative update. We will review the status of key federal and state legislative efforts regarding health services for underserved pediatric/adolescent populations.
Come and join us as we work to improve health services and STUS related teaching for underserved pediatric and adolescent populations.

8:30am - 11:30am
WORKSHOPS
Requires advance enrollment

WS01 Ccmpetency-Based Approach to Community Pediatrics: Service Learning Methodology
Competency-based education has become a top priority in medical training. It places the emphasis in integrating knowledge, skills and attitudes into the actual performance of the essential tasks of an effective practicing pediatrician. In the field of Community Pediatrics, it has been particularly difficult to define the competencies necessary to become an effective community advocate. Our Community Pediatrics program has achieved a comprehensive competency-based approach to training by incorporating Service Learning as the core of the educational experience. Service learning integrally involves the community in the design and implementation of the curriculum. It combines specific learning objectives with community service, evaluation and reflection. With this educational methodology, competencies are defined mutually by members of the community and the academic medical center.

Participants in this workshop will: 1) Develop competency statements in the area of Community Pediatrics, 2) Identify appropriate educational methods to achieve those competencies, with particular emphasis in Service Learning and 3) Explore appropriate methods for evaluating the residents’ mastery of the articulated competencies

D. Meyer, M. McCord, P. Hametz, M. Irigoyen, M. Batista, and V. LeBlanc

WS02 A Systematic Approach to Curriculum Development
As the clinical venues and topics continue to evolve in pediatric education, faculty are being asked to revise or develop new curricula. Unfortunately, the medical education literature provides little guidance in the specific steps required to develop educationally sound clerkships and rotations. In this workshop, participants will learn a validated model for developing medical curricula. The model has been successfully used with faculty development fellows at Michigan State University for the past decade. At the end of this workshop, participants will be able to: 1) develop curricula using the model, and 2) explain the political and communication issues involved in getting curricula adopted.

The workshop format will include a simulated curriculum development task, brief presentations of essential concepts, and small group activities with feedback. Participants will be provided with an extensive take-home curriculum development manual.

Anne Armstrong-Coben, Columbia University, New York, NY; and William A. Anderson, Michigan State University, East Lansing, MI

9:15am - 12:00noon
MINI COURSES

Update in the Genetics of Renal and Liver Tumors in Childhood
Chair: Gail Tomlinson, University of Texas Southwestern Medical Center, Dallas, TX

This course will provide up-to-date information on genetics and epidemiology of renal and liver tumors in children, including Wilms tumor and hepatoblastoma. We will discuss recent findings in germ-line mutations and familial associations. The course will inform the clinician of the emerging association of hepatoblastoma and premature and low-birth weight infants and introduce strategies for cancer surveillance in the high-risk child.

Cytogenetics of Renal and Liver Tumors in Children
Nancy R. Schneider, University of Texas Southwestern Medical Center, Dallas, TX

Cancer Surveillance for Overgrowth Syndromes
Michael R. DeBaun, Washington University School of Medicine, St. Louis, MO

Hepatoblastoma and Prematurity
James Feusner, Children’s Hospital, Oakland, CA

Genetics of Wilms Tumor
Max Coppes, Invited, Alberta Children's Hospital, Alberta, Canada

Sponsored Jointly with the American Society of Pediatric Hematology/Oncology

Von Willebrand Disease: New Insights into the Pathophysiology, Diagnosis and Treatment 
Chair: Sara J. Israels,University of Manitoba, Winnipeg,Canada

This 3-hour mini course will update primary and subspecialty care providers on the advances in our understanding of von Willebrand Disease, the most common inherited bleeding disorder. The minicourse will provide an overview of both basic and clinical aspects of this disease, including discussion of the biochemistry and genetics of von Willebrand Factor, dilemmas in the diagnosis of this highly variable disease, and advances in the management of children and adolescents with von Willebrand Disease. Congenital platelet function abnormalities, which share clinical similarities with von Willebrand Disease, will also be discussed.

The Biology and Molecular Genetics of von Willebrand Factor and von Willebrand Disease
J. Evan Sadler, Howard Hughes Medical Institute and Washington University School of Medicine, St Louis, MO

Approach to the Diagnosis of von Willebrand Disease
Robert R. Montgomery, Medical College of Wisconsin and the Blood Research Institute of the Blood Center, Milwaukee, WI

Management of Children and Adolescents with von Willebrand Disease
Donna DiMichele, New York Hospital/Cornell Medical Center, New York, NY

Congenital Disorders of Platelet Function
Sara J. Israels, University of Manitoba, Winnipeg, MB, Canada

Sponsored Jointly with the American Society of Pediatric Hematology/Oncology

10:00am - 1:00pm
EDUCATIONAL SEMINAR
Requires advance enrollment

ES13 Recognizing Common Biostatistical Errors: A Case-Based Approach

Back by popular demand, this seminar uses multiple real examples from the pediatric literature to teach participants how to be more discriminating consumers of statistics. Topics to be covered include standard deviation vs. standard error of the mean, commonly violated assumptions of statistical tests, including normality and independent sampling, between-vs. within-groups comparisons, "type 3" (dumb or careless) errors, odds ratios versus risk ratios, relative versus absolute effect sizes, and multiple comparisons. In the last part of the seminar, participants will have the opportunity to test what they’ve learned on a set of "unknown" examples.
Thomas B. Newman, Professor, University of California, San Francisco, CA and Yvonne Wu, Clinical Instructor, University of California, San Francisco, CA

11:00am - 1:00pm
EDUCATIONAL SEMINARS
Requires advance enrollment

ES14 A Researcher's Approach to Funding Problems in an Academic Medical Center
Elements of managed care and uncertainty in research funding have substantially increased the financial pressure on many academic medical centers. This educational program will review and discuss new financial analysis techniques that eliminated a hospital’s unit deficit of more than $2,000,000 within 4 months, provided nearly $1,000,000 in unrestricted funding for a new research institute, and significantly improved the collection process of professional fees. All these outcomes were accomplished without the added benefits/risks of cost-cutting programs. At the completion of this seminar, participants will have a clearer understanding of their role in the fiscal health of their academic centers as well as have specific tools and approaches with which they can assess and possibly improve the fiscal health of their respective institutions or professional practices.
David T. Tanaka, Associate Clinical Professor of Pediatrics, Duke University Medical Center, Durham, NC

ES15 Career Paths for Clinician-Educators: Planning and Moving Ahead in Your Career as a Clinician-Educator
Clinician educators are those physicians whose career activities combine patient care and the teaching and supervision of medical students and residents, and whose scholarly activities promote excellence in medical education.
With this workshop, it is expected that participants will:
1. have a better understanding of the motivations and works responsibilities of clinician-educators, and will be able to compare the motives for their careers with those of other clinician-educators.
2. learn how a mentoring program can help the clinician-educator plan and develop his/her career.
3. have a better understanding of specific faculty development activities (workshops, microteaching, teaching evaluations, teaching consultations) and the evidence for the effectiveness of these activities.
4. have a better understanding of the evaluation of teachers and how these evaluations are used for faculty development, promotion and compensation, and will learn guidelines for developing an effective Teaching Dossier which can be the key to successful promotion.
Robert I. Hilliard, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, Karen Leslie, Division of Adolescent Medicine, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada and Ann Jefferies, Division of Neonatology, Mount Sinai Hospital, Toronto, ON, Canada

ES16 Career Paths in Academic Medicine: Basis Science
The physician scientist is the individual who is most responsible for helping translate the basic sciences into clinically important investigations. Given the increasing difficulties in obtaining funding as either a physician or a scientist, some people have questioned the viability of this hybrid. We will discuss the necessary background, environment, support and mentoring necessary to train and sustain the physician scientist in a complex and changing environment. Individuals choosing either laboratory or other basic sciences as major components of their career are encouraged to attend.
Frederick J. Suchy, Professor and Chair, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY

ES17 Effective Scientific Presentation (Session limited to 75)
Presenting scientific information clearly is an essential part of a successful scientific career. Colleagues will infer your scientific ability from the clarity and quality of your oral presentations. Presentation skills can be learned and improved. In this seminar, we will discuss the following topics:
- Organizing your presentation
- Choosing audio-visual aids
- Making effective slides
- Presenting data
- Handling questions
- Practical hints
Thomas A. Hazinski, Professor of Pediatrics, Associate Chair for Academic Affairs, Vanderbilt University Medical Center, Nashville, TN

ES18 Effective, Efficient, and Innovative Medical Student and Resident Teaching: Who Says It Can't Be Done?
With increased pressures to treat patients as efficiently as possible, teaching of medical students and residents has become more of a burden or even an afterthought and less of a major priority in the clinical setting. Effective, efficient, and innovative teaching strategies are needed. This seminar will provide participants with such strategies that will in turn aid in the recruitment, faculty development, and retention of preceptors. Mock teaching codes, videotapes, and other live demonstrations will be used to highlight the techniques and innovations to be introduced. Content areas will focus on the importance of a good orientation, feedback, evaluation, and creative teaching techniques that will make teaching fun and a true learning experience for all involved.
Lewis First, Professor and Chairman, Department of Pediatrics, University of Vermont College of Medicine, Burlington, VT

ES19 Increasing Skills in Giving and Receiving Feedback (Session limited to 25)
The purpose of this seminar, which is designed for junior faculty, fellows, and residents, is to provide an opportunity for participants to increase their comfort in giving and receiving feedback in an educational setting. Although physicians are expected to give and receive feedback throughout their experiences as students, teachers, researchers, and clinicians, these skills are seldom discussed as components in the process of teaching and learning. This session will include self-reflective, interactive, and role-playing exercises.
John M. Leventhal, Professor of Pediatrics, Yale University School of Medicine, New Haven, CT and Mary Anne Johnston, Assistant Professor, Department of Internal Medicine, University of Colorado Health Science Center, Denver, CO

ES20 Manuscript Preparation and the Process of Peer-Reviewed Publication
This workshop will address multiple aspects of publication in scientific journals. Presenters will discuss preparation of materials, including the initial decision that the data are sufficient to justify publication. Issues related to manuscript writing will include length, focus, adherence to journal formats, and referencing. The editorial process, from submission to publication, will be described in depth, with particular attention to ways in which authors can interact with journal editors. Another section of the workshop will cover ethical issues in publication including review boards, authorship, duplicate publication, intellectual property rights, and conflict of interest. There will be open discussion of sample cases and questions derived from the experiences of the participants.
Thomas R. Welch, Louise M. Williams Professor of Pediatrics, Children’s Hospital Medical Center, Cincinnati, OH, Stephen R. Daniels, Professor of Pediatrics and Environmental Health, Children’s Hospital Medical Center, Cincinnati, OH, and Alan H. Jobe, Professor of Pediatrics, Children’s Hospital Medical Center, Cincinnati, OH

ES21 Opportunities for Leadership
This workshop will discuss the multiple paths to academic leadership. There will be three distinct perspectives presented: leadership at an institutional level—climbing the academic ladder; leadership at an organizational level—opportunities to become involved with national organizations such as the American Academy of Pediatrics, the Ambulatory Pediatric Association, American Pediatric Society, Society for Pediatric Research; and networking: differences in gender styles and opportunities. There will be individual presentations about personal career paths by each of the four panelists with an opportunity for workshop participants to discuss their personal experiences.
Carol D. Berkowitz, Professor, Harbor/UCLA Medical Center, Torrance, CA and Philip Pizzo, Harvard Medical School, Children’s Hospital, Boston, MA

ES22 Publish/Don't Perish!
The publication and dissemination of new knowledge has long been the goal standard of academic pediatrics. However, inertia remains a substantial barrier to successful publications and presentations for many faculty. A well-organized and systematic approach to the presentation of scientific data can substantially reduce the impediments to success and lead to high-quality and well-received efforts. This seminar will take a practical and focused approach to the conceptualization, derivation and presentation of scientific material to be presented as a manuscript, abstract or oral presentation. Group discussions, critique and analysis will be an inherent component of this seminar.
Norman Siegel, Professor of Pediatrics and Medicine, Interim Chair and Physician-in-Chief, Department of Pediatrics, Yale University School of Medicine, Yale-New Haven Children’s Hospital, New Haven, CT

ES23 Survival Skills for Pediatric Fellows
This workshop is intended to help pediatric fellows and young junior faculty with challenges they face at each stage of their training including: how to identify worthwhile research projects, how to apportion time between research and course work, how to choose and work with a mentor, how to complete projects during one’s fellowship, when and how to write grants, how to get and negotiate a job, how to balance career and family, and how to transition to life as a junior faculty member. This workshop will be of particular interest to current pediatric fellows of any year, but it will also provide useful insights for those who recently completed or are considering a fellowship. The facilitators will include faculty at all stages of their career and will include both clinician scientists and clinician educators. There will be ample time for open discussion and question and answer.
Dimitri A. Christakis, Assistant Professor Pediatrics, Co-director of Child Health Institute, University of Washington, Seattle, WA

ES24 The Art and Science of Negotiating for Faculty Position: A Practical Guide for Fellows and Junior Faculty
The process of interviewing and negotiating for a faculty position is a common experience of most fellows, and many residents and junior faculty. There is little, if any, training in this process. This seminar will 1) identify key concepts of the interviewing and negotiation process, 2) increase the awareness of residents, fellows and junior faculty of these concepts when applying for positions in academic medicine, and 3) develop skills in utilizing them. These concepts include preparation for, and elements of, the first and subsequent interviews, stages and styles of the negotiation process, and core issues such as compensation, office space, research resources, promotion guidelines and family considerations. Brief didactic presentations and case-directed discussions will highlight these concepts. Participants will have the opportunity to apply concepts learned to simulated interview situations.
Thomas G. DeWitt, Professor and Director, Division of General and Community Pediatrics, Children’s Hospital Medical Center, Cincinnati, OH

ES25 The Promises and Pitfalls of Multi-site Collaborative Research
This session will provide participants with the necessary background for developing and conducting successful multi-site collaborative research projects in inpatient and outpatient settings. The co-leaders, who have overseen numerous diverse multi-site observational studies and clinical trials, will begin the session with a focused presentation outlining the rationale for multi-site collaborations, the principles of successful collaboration, and the potential pitfalls of this type of research, answering questions about these issues. Subsequently, they will lead the participants in a step-by-step exercise of planning, developing and implementing one inpatient and one outpatient study suggested by the audience.
Richard C. (Mort) Wasserman, Professor of Pediatrics, University of Vermont College of Medicine, Burlington, VT and Roger F. Soll, Professor of Pediatrics, University of Vermont College of Medicine, Burlington, VT

ES26 Women in Academic Medicine: Balancing Strategies
This seminar will focus on the unique issues related to the challenges of women in academic medicine. The first topic will be the various tracks within the academic community, and the expectations related to promotion within these tracks. The second topic to be discussed will be maintaining a balance between professional and personal life, and the presentation will include a discussion of the pros and cons, and ups and downs of part-time employment. The last issue to be discussed will be negotiation skills for women in academia. Problematic scenarios will be presented and strategies for solutions will be proposed.
Phyllis A. Dennery, Associate Professor and Associate Division Chief, Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA and Susan B. Shurin, Professor of Pediatrics, Rainbow Babies and Children’s Hospital and Case Western Reserve University, Cleveland, OH

12noon - 3:00pm
MINI COURSES

Changing Patterns of Chronic Health Conditions in Children
Chair: James M. Perrin, Mass General Hospital for Children, Boston, MA

Approaches to the diagnosis, prevention, and treatment of chronic conditions in childhood and adolescence have changed greatly with greater survival of most children, even with severe conditions. Thus, for most children, new issues include preparation for adulthood rather than expectation of early death. Community pediatricians have increasing numbers of children with chronic conditions in their practices and thereby face new challenges in the care of these children and their families. Advances in molecular biology and genetics will lead to more effective ways to identify and treat many conditions. At the same time, children and adolescents face a great rise in new epidemics of chronic conditions, with marked increases in obesity, asthma, Type 2 diabetes, mental health conditions (especially ADHD and depression). This session will examine new advances in the biology of chronic conditions, important changes in epidemiology, consideration of important outcomes for children and adolescents with chronic conditions, and new efforts to improve their pediatric care.

New Morbidities: Clinical and Social Changes in Childhood Chronic Conditions
James M. Perrin, Mass General Hospital for Children, Harvard Medical School, Boston, MA

Prospects for New Treatments
Alan B. Ezekowitz, Mass General Hospital for Children, Boston, MA

Improving the Care of Children with Chronic Illness
Carole M. Lannon, University of North Carolina, Chapel Hill, NC

Outcomes of Chronic Conditions: What Should We Measure?
Ruth E. K. Stein, Albert Einstein College of Medicine/Children’s Hospital at Montefiore, Bronx, NY

Sponsored Jointly with the American Academy of Pediatrics

Enabling Technologies in Genetics and Genomics
Chair: Robert Nussbaum, National Human Genome Research Institute, Bethesda, MD

This minicourse will highlight new technologies in genetics and genomics that build on the mapping and sequencing of human and model organism genomes to define the function of genes and their clinical importance in normal health and disease.

Genetic Analysis of Hematopoiesis and Cancer
Leonard I. Zon, Howard Hughes Medical Institute, Children’s Hospital, Boston, MA

Genetic Polymorphisms for Linkage and Association Studies
Aravinda Chakravarti, Johns Hopkins University School of Medicine, Baltimore, MD

Gene Expression: Expression Profiling and Microarray Technology
Jeffrey M. Trent, National Institute of Health, National Human Genome Research Institute, Bethesda, MD

Oxidant Stress and Free Radical Damage in Human Subjects and Experimental Models: Methods and Data Interpretation
Chairs: Charles V. Smith, Children’s Research Institute, Ohio State University, Columbus, OH and Stephen E. Welty, Children’s Research Institute, Ohio State University, Columbus, OH

Reactive oxygen species contribute to diseases in prematurely born infants as well as aging adults. These reactive species are studied by various analytical methods based on chemical principles that are incompletely understood. The purpose of this workshop is to provide useful overviews and critical assessments of the limitations of the commonly used methods for measurement of oxidant stress responses, with particular emphasis on the application of these methods to studies in pediatric patient populations. Sample acquisition and handling, activation and effect of inflammatory responses, lipid peroxidation, thiol/disulfide redox status, protein nitration and other nitric oxide-medicated modifications, and measurement and characterization of dinitrophenylhydrazine-reactive "protein carbonyls" will be discussed. In addition to practical considerations, the utility and limitations of the data obtained with these methods will be addressed.

Introduction and Overview

Inflammation as a Cause and Effect of Oxidant Stress
Stephen E. Welty, Children’s Research Institute, The Ohio State University, Columbus, OH

Sample Acquisition and Handling
Patricia L. Ramsay, Baylor College of Medicine, Houston, TX

Lipid Peroxidation: From Malonaldehyde to Isoprostanes
Jason D. Morrow, Departments of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, TN

Nitric Oxide and Other Reactive Nitrogen Species
Harry Ischiropoulos, Joseph Stokes, Jr., Research Institute, Philadelphia, PA

Protein and Nucleic Acid Oxidation
Charles V. Smith, Children’s Research Institute, The Ohio State University, Columbus, OH

Discussion

Also See Mini Course 2:00pm-5:00pm

12noon - 3:00pm
WORKSHOPS
Requires advance enrollment

WS03 Ccnstructing and Presenting Workshops that Work
Workshops are a popular and versatile method of teaching adults. From teaching a procedure to teaching how to teach, from local departmental retreats to national meetings, from precepting students to working to develop the skills of colleagues, workshops are widely used in medical education. This workshop will give participants the tools/framework necessary to construct and lead their own effective workshops. Facilitators of this workshop are from a variety of institutions and are participants in the APA national Pediatric Faculty Development Scholars Program, a project to develop regional faculty development training expertise. We will draw from our experiences in this program and the literature on education to review concepts of adult learning theory and techniques for working with small groups. Through participatory and interactive segments, the group will address how to conduct a needs assessment of the target audience and use the results to plan an effective workshop. Techniques for effective communication, use of audio-visual supplements, and evaluation will be covered. Various techniques for role-playing and audience participation and interaction will be demonstrated. Breakout sessions will allow participants to practice some of the skills that are taught. Participants will receive a listing of national Pediatric Faculty Development Scholars by region to facilitate further networking and long-range access to workshop development expertise.

E. A. Zenni, J. S. Andrake, L. M. Pasquinelli, J. G. Christner, S. Wong and T. C. Shope, Department of Pediatrics, University of Florida Health Science Center, Jacksonville, FL

WS04 Evaluation and Treatment of Pediatric Obesity: Practical Strategies for Primary Care Providers
The U.S. is experiencing an epidemic of pediatric obesity. However, many primary care providers report that obesity is one of the most frustrating and difficult problems in their practices. In this workshop, we will provide practical strategies for evaluating and treating obese children in primary care. To maximize learning and relevance the session will be split. During the first third of the session, we will present expert committee recommendations for evaluation and behavioral treatment strategies. We will address skills for identification of obesity, screening for both rare endogenous causes of obesity and more common obesity-associated conditions or risk factors, assessment of emotional and psychosocial states, eating and activity assessment, and indications for consultation with an obesity specialist. For
treatment, we will address the most successful strategies for diet and physical activity counseling, changing the household environment, self- monitoring, goal setting and contracting, parenting skills training, maintenance and relapse prevention, and the potential role of drug therapies. The second two-thirds of the session will consist of case discussions and group problem solving. Cases will be provided but attendees will be asked to bring their own cases as well. Several additional experienced obesity specialists will also be present to participate in the case discussions.

T. N. Robinson and S. E. Barlow, Department of Pediatrics, Stanford University, Palo Alto, CA and Department of Pediatrics, St. Louis University School of Medicine, St. Louis, MO

WS05 International Adoption: What the Primary Care Provider Needs to Know
Over 75,000 children, from 36 countries, have been adopted by U.S. families since 1990. During 1998 alone, almost 16,000 children have been internationally adopted. It is quite likely that the primary care provider will encounter at least one internationally adopted child in his or her practice. While most of these children may appear healthy and well nourished, more than 50% have an undiagnosed medical condition at the time of the initial evaluation in the United States, regardless of age, sex, or country of origin. This workshop is designed to educate and alert the participants to the unique medical needs of these children so that early treatment and intervention is optimized. The workshop will familiarize the primary care provider working with international adoptees and will clarify his or her role in caring for the internationally adopted child. The first part of the workshop will focus on the following topics: 1) review medical records (photos, video) of the child from abroad, 2) travel preparation for parents, 3) post-adoptive medical screening, diagnoses, and treatment of medical conditions, 4) immunizations, 5) assessment of growth, development and nutrition, 6) coordinating care of special-needs children, and 7) guidance on adjustment problems, language delays, preparation for preschool and school, adoption procedures, cultural issues. The second part of the workshop will consist of small group discussions involving several case studies. The workshop team consists of general pediatricians, infectious disease experts, developmentalists, and international adoption clinic directors who provide services to a large number of internationally adopted children and their parents throughout the country. Written materials reviewing workshop concepts and a list of adoption clinics will be distributed.

E. E. Schulte, J. E. Aronson, L. M. H. Albers, S. Blatt, Children’s Hospital at Albany Medical College, International Adoption Medical Consultation Services, Mineola, NY, Children’s Hospital, Boston, MA, Department of Pediatrics, Syracuse, NY

WS06 Malpractice and Communication Skills for Difficult Situations
Medical students have not always had access to information and behavior skills training related to malpractice, and communication skills for difficult situations. Perhaps, as a result, some pediatricians become involved in lawsuits that might have been avoided by using interpersonal skills to enhance the physician-patient relationship. Research suggests that many families file malpractice suits when adverse outcomes are associated with poor physician-patient relationships, physicians’ criticism of one another, and unclear communications. This research has led multidisciplinary faculty and risk management staff to develop a 6 hour, small group course for practicing physicians, residents and 4th year medical students taking their 4 week ambulatory pediatrics rotation. The proposed workshop presents a mini version of the course and suggests how it may be adopted elsewhere.

Participants are challenged to: identify patient dissatisfactions that increase risk of suits, communicate effectively in adverse circumstances, relate physician’s interpersonal behaviors to patients’ perception of quality care and understand risk management’s issues and roles. Participants practice with surrogate patients who present 10 cases based on research and actual lawsuits. Scenarios range from a diagnosis of cerebral palsy in which a mother wants to blame her obstetrician to a case of iatrogenic death. The workshop will include a brief lecture, role plays and discussions that focus on: structuring difficult interactions, dealing with patients varied responses to bad news, what to do when you or another physician has erred and principles of risk reduction.

J. Gigante, G. B. Hickson, T. Trotter, J. W. Pichert, Vanderbilt Children’s Hospital, Nashville, TN

WS07 Maximizing Effective Teaching in the Outpatient Setting
Many academic general pediatricians, subspecialty pediatricians and community pediatricians serve regularly as attending physicians in the outpatient setting. In this role both teaching of trainees and supervision of patient care occur concurrently in a busy, often fast-paced environment. The goal of this workshop is to provide strategies for physicians to improve the efficiency and effectiveness of their teaching in the outpatient setting. The workshop will be structured as follows: first, participants will identify features of outpatient settings that facilitate good teaching and will delineate potential barriers to effective teaching. Second, we will develop feasible solutions to the barriers. Third, we will identify efficient outpatient teaching strategies that incorporate principles of adult learning. Fourth, we will discuss examples of successful outpatient teaching programs at both our own institution and participants’ institutions. Fifth, we will examine and then role-play difficult teaching situations. Finally, we will review the principles and challenges of giving feedback in this setting. Participants will be asked to share their own insights, experiences, and effective outpatient teaching strategies/programs.

P. H. Kaleida, K. Rajakumar, D. L. Bogen, Department of Pediatrics, University of Pittsburgh School of Medicine and Children’s Hospital of Pittsburgh, Pittsburgh, PA

WS08 Understanding Multivariate Regression: A Case-Based Approach
Objective: To enable clinicians to evaluate and interpret results of studies which utilize multivariate regression analytic techniques.

Introduction: Medical journals increasingly publish clinical observational studies which utilize complex statistical analyses. Because treatment and prevention recommendations may be founded on such studies, clinicians need to understand the basic principles of multivariate regression to appropriately evaluate and interpret these results.

Course: This workshop will utilize a case-based teaching approach to illustrate how multivariate regression techniques work, when they are appropriate, and how they are interpreted. The participant will understand how to evaluate and interpret studies which use multivariate analytic models. Minimal computer and math skills are necessary. We will begin by defining confounding in an example study and how it is distinguished from bias. Next we will define/calculate crude odds ratios and confidence intervals using data sets from studies of common pediatric emergency diagnoses as examples. We will then explain and demonstrate the results from the same datasets using logistic regression to adjust for confounding. This case based approach will be repeated using an example of simple linear and multiple linear regression. In the final portion of the workshop, we will discuss how to detect inappropriate/inadequate presentations of multivariate regression, including lack of model diagnostics, unstable models, lack of model validation and co-linearity of variables.

Robert Wright, Jacqueline Grupp-Phelan, Nathan Kuppermann, Divisions of Emergency Medicine, Brown University, Providence, RI, University of Cincinnati, Cincinnati, OH, University of California-Davis, Davis, CA

WS09 Use of Telemedicine to Provide Inpatient and Outpatient Pediatric Services for Underserved Rural Areas
Providing pediatric subspecialty care to underserved rural communities has been a long-standing challenge. Several different health care delivery models have addressed this issue, the most common being outreach outpatient clinics with
travelling Pediatric subspecialty teams based at tertiary children’s centers. This workshop will expose the participant as to how we have utilized telemedicine, live 2 way video linkages, between the rural health care centers and our children’s center. We provide 3 types of pediatric patient care: 1) Outpatient subspecialty consultation and follow-up, 2) PICU to rural adult ICU/adult intensivists for critically ill children, 3) Rural emergency rooms to our pediatric emergency room for acutely ill and injured children. Although the model of outpatient consultation is well established, the PICU to Adult ICU is a new model and has many challenges and opportunities that will be discussed. These include acceptance of a rural partner, ability of the PICU to triage and control all patient flow and beneficial relationships derived by supporting appropriate patients to remain in the local community. The rural ER to pediatric emergency room model involves a complex electronic network but is well received in rural communities. A limited discussion of technical details will also be available.

R. J. Dimand, J. P. Marcin, H. J. Kallas, Department of Pediatrics, University of California-Davis, Sacramento, CA

WS10 Violence and the Pediatric Patient: Reality Hits Hard
The repercussions of violence affect pediatric patients and their families every day. Many residency training programs struggle with how to address this new epidemic. This workshop presents a model of a creative, comprehensive violence assessment and prevention curriculum, encouraging medical educators to explore new teaching methods. We hope to stimulate a lively discussion of educational strategies: didactic presentations, multimedia demonstrations, standardized patient interviews, community resource displays and evaluation methods. Attendees will be trained in case-based role-play scenarios to facilitate learners’ communication skills within the patient-physician encounter. The workshop will offer specific didactic outlines and examples of pertinent videotapes and community resource displays as springboards for conversation regarding improvement of resident violence education. The model suggests one evaluation method that reinforces the newly acquired competencies via the creation of learner contracts. Small group discussions will be used to generate new ideas in violence-related curriculum development and evaluation.

Shannon Phillips, Jill Mazurek, Mary Ciccarelli, Marilyn Bull, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN

12noon - 3:00pm
APA COMMITTEES

1:00pm - 3:00pm
SUBSPECIALTIES/THEMES (Original Science Abstract Programs)
Hematology and Oncology I
(special time for this single program)

2:00pm - 5:00pm
MINI COURSE

Diabetes Mellitus
Chairs: Patricia A. Donohoue, University of Iowa Hospitals and Clinics, Iowa City, IA and Desmond A. Schatz, University of Florida, Gainesville, FL

This 3-hour minicourse will help the primary and subspecialty care providers understand better the changing field of diabetes mellitus: its pathophysiology, epidemiology, and advances in management. The availability of new treatments and devices for the care of patients with Type I diabetes has changed dramatically over the past decade. The rising prevalence of Type 2 diabetes, closely linked to the obesity epidemic, is bringing a formerly "adult" disease into the pediatricians’ offices. This minicourse will provide an overview of four pertinent areas, by speakers who are leaders in the field.

Cell Biology of Human Pancreatic Islets
Alberto Hayek, University of California San Diego Medical School, La Jolla, CA

Islet Transplantation in Humans: 2001 and Beyond
R. Paul Robertson, Pacific Northwest Research Institute, Seattle, WA

Break

Type 2 Diabetes in Childhood and Adolescence
Francine R. Kaufman, Children’s Hospital of Los Angeles, USC School of Medicine, Los Angeles, CA

Novel Devices and Products for Diabetes Management
William V. Tamborlane, Yale University School of Medicine, New Haven, CT

Sponsored Jointly with the Lawson Wilkins Pediatric Endocrine Society

3:15pm - 5:15pm
SUBSPECIALTIES/THEMES (Original Science Abstract Programs)

Adolescent Medicine I
Behavioral Pediatrics I 
Education I 
Emergency Medicine I 
Historical Perspectives 
Mechanisms Involved in Neonatal Diseases 
Molecular Basis of Renal Development and Disease 
Neonatal Feeding and Nutrition
Nutritional Issues in Underserved Populations
Understanding Lung Injury: Nature or Nurture

3:15pm - 5:15pm
TOPIC SYMPOSIA

Molecular Advances in Hematology/Oncology (New Diagnostic and Therapeutic Approaches)
Chair: Robert Arceci, Johns Hopkins Oncology Center, Baltimore, MD

Much attention has been given to advances in molecular biology, the genome project, immunobiology and rational drug design based on sound scientific discoveries. While there has been much excitement generated by such areas, an often expressed concern is "Where's the beef?" This session will attempt to describe several examples of how advances in laboratory science are now being translated into more effective treatments for diseases that have evaded more conventional therapeutic approaches.

AML as a Model for Novel Cancer Therapeutics
Robert J. Arceci, Johns Hopkins Oncology Center, Baltimore, MD

Nonmyeloablative Transplants and Novel Conditioning Approaches
Stella M. Davies, University of Minnesota, Minneapolis, MN

New Therapeutic Approaches for Sickle Cell Disease
James F. Casella, Johns Hopkins School of Medicine, Baltimore, MD

Sponsored Jointly with the American Society of Pediatric Hematology/Oncology.

Do Single Gene Disorders Exist?
Chairs: Katrina M. Dipple and Edward R. B. McCabe, University of California School of Medicine, Los Angeles, CA

As we entered the molecular genetics era, the hope had been that correlation of mutations with clinical course would permit accurate prediction of prognosis with future patients. However, as increasing information has been accumulated, what has emerged has been the recognition that clinical variability among individuals with identical mutations is the rule, not the exception. We will explore mechanisms for clinical variability, including protein activity, thresholds, modifier genes, and system complexity.

Complexity of Single Gene Disorders
Edward R. B. McCabe,University of California School of Medicine, Los Angeles, CA

Even PKU is Not a Simple Mendelian Disorder
Charles R. Scriver, McGill University, Montreal, Canada

CF as a Complex Trait Genetically
Garry R. Cutting, Johns Hopkins School of Medicine, Baltimore, MD

Muscle Diseases as Models of Complexity
Georgirene D. Vladutiu, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY

Supported by an educational grant from the March of Dimes Birth Defects Foundation

4:30pm - 7:30pm
COMMERCIAL EXHIBITS OPEN AND POSTERS AVAILABLE FOR VIEWING
Available for Viewing - 4:30pm - 7:30pm
Author Attendance
-
5:15pm - 7:15pm

5:15pm - 7:15pm
POSTER SESSION I & OPENING RECEPTION

Adolescent Medicine:
          HIV/Sexualtiy/STDs

          General (Misc)
Behavioral Pediatrics:
          Infant Crying
          Drug-Exposed Infants
          ADHD
          Literacy Promotion
          Chronic Conditions
          Schools
          General (Misc)
Education:
          Resident Continuity Clinic
          Resident
          Faculty
          Student
          Parent Education
Endocrinology:
          Obesity
          Insulin and Diabetes:  Basic and Clinical
General Pediatrics:
          Media and Children
          Health Services Research
          Environmental Health
Hematology/Oncology
          Hemoglobinopathies
          Idiopathic Thrombocytopenic Purpura/Platelets
          Hemophilia/Coagulations Disorders
          Anemia/Marrow Failure
          Cellular/Molecular Biology
Neonatology
          Oxidants and Antioxidants
          Persistent Pulmonary Hypertension
          Lung Injury
          Lung Mechanics and Ventilation
          Bronchopulmonary Dysplasia/Chronic Lung Disease
          Pulmonology: Nitric Oxide
          Lung Miscellanous
Nephrology
          Clinical: Disease Models
          Clinical:  Chronic Renal Insufficiency
          Cytokines and Cell Signaling
          Renal Development
          Cell Injury

7:15pm
PERINATAL NUTRITION AND METABOLISM CLUB

7:30pm - 9:30pm
BLOOD CLUB

 

Schedules for:
  Sunday, 4/29
 
Monday, 4/30
 
Tuesday, 5/1

Schedule-at-a-Glance
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Last Modified: September 26, 2006